Antibiotic resistance pattern and gene expression of non-typhoid Salmonella in riversheds

Chao Yu Hsu, Bing Mu Hsu*, Wen Tsai Ji, Jung Sheng Chen, Tsui Kang Hsu, Dar Der Ji, Shao Feng Tseng, Yi Chou Chiu, Po Min Kao, Yu Li Huang

*此作品的通信作者

研究成果: Article同行評審

16 引文 斯高帕斯(Scopus)

摘要

In this study, antibiotic resistance and major phenol and genotypes of non-typhoid Salmonella spp. from riversheds in Taiwan were examined. In 236 water samples tested, 54 (22.9 %) contained Salmonella spp. Fifteen Salmonella serovars were identified from the Salmonella isolates, and some common serovars are associated with infections of human and livestock, including Albany (27.8 %), Newport (14.8 %), Bareilly (13.0 %), Derby (11.1 %), and Typhimurium (7.4 %). Various environmental factors may also affect the presence and proportion of different serovars in the receiving waters. In contrast, serovars with narrower range of hosts, e.g., Dublin, were rarely detected. The Salmonella isolates were subjected to eight antibiotics for drug resistance, and 51.9 % of the samples were resistant to at least one tested antibiotics. Tetracycline and sulfadiazine were the two most ineffective antibiotics against the Salmonella isolates, and the results were indicative of long-term antibiotics abuse as fodder supplements in animal husbandry. The more commonly detected serovars such as Albany, Derby, and Typhimurium were also more likely to be resistant to multiple antibiotics. Finally, a significant correlation was observed between resistance to chloramphenicol and the resistance gene cmlA, suggesting that the resistance genotypes could persist in the environment even long after prohibition of the drug use. The high prevalence of antibiotic-resistant Salmonella spp. infers elevated infection risks that must be further examined.

原文English
頁(從 - 到)7843-7850
頁數8
期刊Environmental Science and Pollution Research
22
發行號10
DOIs
出版狀態Published - 16 5月 2015

指紋

深入研究「Antibiotic resistance pattern and gene expression of non-typhoid Salmonella in riversheds」主題。共同形成了獨特的指紋。

引用此