Age- and sex-related differences in masseter size and its role in oral functions

Chia Shu Lin*, Ching Yi Wu, Shih Yun Wu, Kai Hsiang Chuang, Hsiao Han Lin, Dong Hui Cheng, Wen Liang Lo


研究成果: Article同行評審

21 引文 斯高帕斯(Scopus)


Background The masseter muscle plays a key structural and functional role in the stomatognathic system. Researchers’ cumulative evidence has suggested that the variation in the size of a person's masseter muscle may be a critical factor related to individual differences in oral functions. However, researchers have not yet investigated systematically the effect of a person's age and sex on masseter muscle size and the association of masseter muscle size with other clinical metrics, including masticatory performance (MP) and salivary flow rate (SFR). Using T1-weighted magnetic resonance imaging (MRI) data provides a noninvasive method for assessing masseter muscle volume (MMV). Methods Using T1-weighted MRI data, the authors developed a voxel-based method to assess MMV and investigated the associations among MMV, MP, and SFR. Results The authors acquired T1-weighted MRI data from scans of the heads of 62 healthy adults and assessed MMV by means of using a voxel-based approach. The authors’ assessment results had acceptable rates of inter-rater and intrarater reliability. MMV was significantly lower in the older subgroup and in the female subgroup. In addition, the correlation for MMV was significantly positive with MP and stimulated SFR. Conclusions The study results revealed evidence that the authors’ voxel-based approach, which they designed on the basis of T1-weighted MRI data, would be a reliable method for quantifying MMV. Practical Implications The findings suggest that the variation in masseter muscle size may be a critical factor to assess individual differences in oral functions.

頁(從 - 到)644-653
期刊Journal of the American Dental Association
出版狀態Published - 9月 2017


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