TY - JOUR
T1 - Acute renal failure in severe pancreatitis
T2 - A population-based study
AU - Lin, Hung Yuan
AU - Lai, Jiun I.
AU - Lai, Yi Chun
AU - Lin, Po Chou
AU - Chang, Shih Chieh
AU - Tang, Gau Jun
PY - 2011/5
Y1 - 2011/5
N2 - Introduction. Acute pancreatitis (AP) is a common illness with varied mortality and morbidity. Patients with AP complicated with acute renal failure (ARF) have higher mortality than patients with AP alone. Although ARF has been proposed as a leading mortality cause for AP patients admitted to the ICU, few studies have directly analyzed the relationship between AP and ARF. Methods. We performed a retrospective study using the population-based database from the Taiwan National Health Insurance Research Database (NHIRD). In the period from 1 January 2005 to 31 December 2005, every patient with AP admitted to the ICU was included and assessed for the presence of ARF and mortality risk. Results. In year 2005, there were a total of 221,101 admissions to the ICU. There were 1,734 patients with AP, of which 261 (15.05%) patients also had a diagnosis of ARF. Compared to sepsis and other critical illness, patients with AP had a higher risk of having a diagnosis of ARF, and patients with both diagnoses had a higher mortality rate in the same ICU hospitalization. Conclusion. AP is associated with a higher risk of ARF, and, when both conditions exist, a higher risk of mortality is present.
AB - Introduction. Acute pancreatitis (AP) is a common illness with varied mortality and morbidity. Patients with AP complicated with acute renal failure (ARF) have higher mortality than patients with AP alone. Although ARF has been proposed as a leading mortality cause for AP patients admitted to the ICU, few studies have directly analyzed the relationship between AP and ARF. Methods. We performed a retrospective study using the population-based database from the Taiwan National Health Insurance Research Database (NHIRD). In the period from 1 January 2005 to 31 December 2005, every patient with AP admitted to the ICU was included and assessed for the presence of ARF and mortality risk. Results. In year 2005, there were a total of 221,101 admissions to the ICU. There were 1,734 patients with AP, of which 261 (15.05%) patients also had a diagnosis of ARF. Compared to sepsis and other critical illness, patients with AP had a higher risk of having a diagnosis of ARF, and patients with both diagnoses had a higher mortality rate in the same ICU hospitalization. Conclusion. AP is associated with a higher risk of ARF, and, when both conditions exist, a higher risk of mortality is present.
KW - Acute renal failure
KW - intensive care
KW - severe acute pancreatitis
UR - http://www.scopus.com/inward/record.url?scp=79954544960&partnerID=8YFLogxK
U2 - 10.3109/03009734.2010.547636
DO - 10.3109/03009734.2010.547636
M3 - Article
C2 - 21250932
AN - SCOPUS:79954544960
SN - 0300-9734
VL - 116
SP - 155
EP - 159
JO - Upsala Journal of Medical Sciences
JF - Upsala Journal of Medical Sciences
IS - 2
ER -