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Acidic pH promotes the formation of toxic fibrils from β-amyloid peptide
Yeu Su
*
, Pei Teh Chang
*
此作品的通信作者
生物藥學研究所
研究成果
:
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同行評審
110
引文 斯高帕斯(Scopus)
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深入研究「Acidic pH promotes the formation of toxic fibrils from β-amyloid peptide」主題。共同形成了獨特的指紋。
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Keyphrases
PH Value
100%
Neuronal Cells
100%
Alzheimer's Disease
100%
Acidic pH
100%
Amyloid-β Peptide
100%
Self-assembly
50%
PC12 Cells
50%
In(III)
50%
Neutral pH
50%
Major Components
50%
Structure Effect
50%
Lysosome
50%
Aggregation Behavior
50%
Acidic Environment
50%
Low pH
50%
Apoptotic Cell Death
50%
Cellular Compartments
50%
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide
50%
Amyloid beta
50%
Endosome
50%
Neurodegenerative Processes
50%
Senile Plaques
50%
Phosphatidylserine Externalization
50%
Neurotoxic Effects
50%
MTT Reduction
50%
Neuropathogenicity
50%
Subsequent Effects
50%
Acidic Organelle
50%
Chemistry
Toxic
100%
Neurotoxic
100%
formation
100%
MTT Assay
50%
Apoptotic
50%
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide
50%
Beta-Amyloid
50%
Phosphatidylserine
50%
Neuroscience
Alzheimer's Disease
100%
Amyloid Protein
100%
Behavior (Neuroscience)
50%
Lysosome
50%
Apoptosis
50%
Beta Amyloid
50%
Senile Plaque
50%
Neurodegenerative Process
50%
Phosphatidylserine
50%