Accuracy Evaluation of Collapsed Cone Convolution Superposition Algorithms for the Nasopharynx Interface in the Early Stage of Nasopharyngeal Carcinoma

Yuan Chun Lai, Li Chung Hung, Chien Chung Jeng, Chen Ju Feng, Tung Hao Chang, Shih Ming Hsu*

*此作品的通信作者

研究成果: Article同行評審

摘要

This study combined the use of radiation dosimeteric measurements and a custom-made anthropomorphic phantom in order to evaluate the accuracy of therapeutic dose calculations at the nasopharyngeal air-tissue interface. The doses at the nasopharyngeal air-tissue interface obtained utilizing the Pinnacle and TomoTherapy TPS, which are based on collapsed cone convolution superposition (CCCS) algorithms, were evaluated and measured under single 10×10 cm2, 2×2 cm2, two parallel opposed 2×2 cm2 and clinical fields for early stage of nasopharyngeal carcinoma by using EBT3, GR-200F, and TLD 100. At the air-tissue interface under a 10×10 cm2 field, the TPS dose calculation values were in good agreement with the dosimeter measurement with all differences within 3.5%. When measured the single field 2×2 cm2, the differences between the average dose were measured at the distal interface for EBT3, GR-200F, and TLD-100 and the calculation values were -15.8%, -16.4%, and -4.9%, respectively. When using the clinical techniques such as IMRT, VMAT, and tomotherapy, the measurement results at the interface for all three techniques did not imply under dose. Small-field sizes will lead to dose overestimation at the nasopharyngeal air-tissue interface due to electronic disequilibrium when using CCCS algorithms. However, under clinical applications of multiangle irradiation, the dose errors caused by this effect were not significant.

原文English
文章編號5227609
期刊BioMed Research International
2022
DOIs
出版狀態Published - 2022

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