A sbiT-sbiRS-gloIo regulatory circuit is involved in oxidative stress tolerance of Stenotrophomonas maltophilia

Cheng Mu Wu, Yi Tzu Lee, Hsu Feng Lu, Yen Ling Lin, Tsuey Ching Yang*

*此作品的通信作者

研究成果: Article同行評審

摘要

The sbiT-sbiR-sbiS operon of Stenotrophomonas maltophilia encodes an inner-membrane protein SbiT and a SbiS-SbiR two-component regulatory system. A sbiT mutant displayed a growth defect in LB agar. Mechanism studies revealed that sbiT deletion resulted in SbiSR activation and gloIo upregulation, which increased intracellular ROS level and caused growth defect.

原文English
頁(從 - 到)827-831
頁數5
期刊Journal of Microbiology, Immunology and Infection
57
發行號5
DOIs
出版狀態Published - 10月 2024

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