A novel pseudo resistor structure for biomedical front-end amplifiers

Yu Chieh Huang*, Tzu Sen Yang, Shun His Hsu, Xin Zhuang Chen, Jin-Chern Chiou

*此作品的通信作者

研究成果: Conference contribution同行評審

6 引文 斯高帕斯(Scopus)

摘要

This study proposes a novel pseudo resistor structure with a tunable DC bias voltage for biomedical front-end amplifiers (FEAs). In the proposed FEA, the high-pass filter composed of differential difference amplifier and a pseudo resistor is implemented. The FEA is manufactured by using a standard TSMC 0.35 μm CMOS process. In this study, three types FEAs included three different pseudo resistor are simulated, fabricated and measured for comparison and electrocorticography (ECoG) measurement, and all the results show the proposed pseudo resistor is superior to other two types in bandwidth. In chip implementation, the lower and upper cutoff frequencies of the high-pass filter with the proposed pseudo resistor are 0.15 Hz and 4.98 KHz, respectively. It also demonstrates lower total harmonic distortion performance of -58 dB at 1 kHz and higher stability with wide supply range (1.8 V and 3.3 V) and control voltage range (0.9 V and 1.65 V) than others. Moreover, the FEA with the proposed pseudo successfully recorded spike-and-wave discharges of ECoG signal in in vivo experiment on rat with pentylenetetrazol-induced seizures.

原文English
主出版物標題2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
發行者Institute of Electrical and Electronics Engineers Inc.
頁面2713-2716
頁數4
ISBN(電子)9781424492718
DOIs
出版狀態Published - 4 11月 2015
事件37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
持續時間: 25 8月 201529 8月 2015

出版系列

名字Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
2015-November
ISSN(列印)1557-170X

Conference

Conference37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
國家/地區Italy
城市Milan
期間25/08/1529/08/15

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