A new schema to identify S-farnesyl cysteine prenylation sites with substrate motifs

Van Nui Nguyen*, Thi Xuan Tran, Hai Minh Nguyen, Hong Tan Nguyen, Tzong Yi Lee

*此作品的通信作者

研究成果: Conference contribution同行評審

1 引文 斯高帕斯(Scopus)

摘要

Protein prenylation is the addition of hydrophobic molecules to a protein or chemical compound. It is a post-translational modification that plays very important roles for many cellular processes such as DNA replication, signaling, trafficking, and other cellular functions in eukaryotes. Protein S-farnesyl cysteine prenylation is a specific kind of prenylation involved in the transfer of a farnesyl moiety to a cytoplasmic cysteine at or near the C-terminus of the target protein. Recent advancements in proteomic technology have stimulated an increasing interested in the identification of protein S-farnesyl cysteine prenylation sites. However, there is still a lack of methods proposed for the prediction of S-farnesyl cysteine sites. With a rapidly increasing number of experimentally verified S-farnesyl cysteine sites, it is motivated in proposed new method for identifying S-farnesyl cysteine prenylation sites.

原文English
主出版物標題Advances in Information and Communication Technology - Proceedings of the International Conference, ICTA 2016
編輯Trung-Nghia Phung, Van-Nam Huynh, Masato Akagi, Duc-Thai Vu, Thanh-Thuy Nguyen
發行者Springer Verlag
頁面73-83
頁數11
ISBN(列印)9783319490724
DOIs
出版狀態Published - 2017
事件Proceedings of the International Conference on Advances in Information and Communication Technology, ICTA 2016 - Thai Nguyen, 越南
持續時間: 12 12月 201613 12月 2016

出版系列

名字Advances in Intelligent Systems and Computing
538 AISC
ISSN(列印)2194-5357

Conference

ConferenceProceedings of the International Conference on Advances in Information and Communication Technology, ICTA 2016
國家/地區越南
城市Thai Nguyen
期間12/12/1613/12/16

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