A New Homoisoflavonoid and Anti-Inflammatory Constituents from Polygonatum alte-lobatum

Chieh Yang Cheng, Chien Ming Huang, Chien Liang Lin, Tsung Hsien Chang, Ping Jyun Sung, Ming Jen Cheng*, Jih Jung Chen*

*此作品的通信作者

研究成果: Article同行評審

摘要

A new homoisoflavonoid, (R)-3-(2,4-dihydroxybenzyl)-5,7-dihydroxy-8-methoxychroman-4-one (1), has been isolated from the rhizomes of Polygonatum alte-lobatum, together with seven known compounds (2–8). The structure of the new compound 1 was determined through spectroscopic and MS analyses. Among the isolated compounds, compounds 1, 3, 5, and 6 showed potent inhibition with IC50 values of 18.04 ± 2.14, 19.87 ± 2.70, 16.88 ± 1.35, and 18.50 ± 1.52 μM, respectively, against LPS-induced NO generation.

原文English
頁(從 - 到)428-431
頁數4
期刊Chemistry of Natural Compounds
60
發行號3
DOIs
出版狀態Published - 5月 2024

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