A multi-modal sweat sensing patch for cross-verification of sweat rate, total ionic charge, and Na+ concentration

Zhen Yuan, Lei Hou, Mallika Bariya, Hnin Yin Yin Nyein, Li Chia Tai, Wenbo Ji, Lu Li, Ali Javey*

*此作品的通信作者

研究成果: Article同行評審

65 引文 斯高帕斯(Scopus)

摘要

Sweat sensors introduced in recent years have targeted a variety of sweat features and biomarkers for non-invasive health monitoring. Amongst these targets, reliable monitoring of sweat rate is crucial due to its modulation of sweat analyte concentrations and its intrinsic significance to numerous medical and physiological health conditions. Here we present a sweat rate sensor structure comprising of electrodes with interdigitated fingers in a microfluidic channel. Each time the accumulating sweat impinges on an electrode finger, the sensor reports a jump in admittance that can be simply and efficiently counted to estimate sweat rate, overcoming selectivity limitations of previously reported sweat rate sensors. We further integrate an impedimetric sensor for measuring total ionic charge concentration and an electrochemical Na+ sensor, together creating a multi-modal system for analyzing fluid and electrolyte secretion. We demonstrate how low analyte diffusion rates through this microfluidic device allow for multi-purpose sensor function, including utilizing the sweat rate sensor signal to corroborate total ionic sensor measurements. This cross-verification capability ensures data integrity in real time, satisfying a vital consideration for personalized healthcare technologies. We use the presented patch for continuous analysis of sweat rate, total ionic charge concentration, and Na+ concentration during exercise, while demonstrating how multi-modal cross-verification brings new trust to sensor readings.

原文English
頁(從 - 到)3179-3189
頁數11
期刊Lab on a Chip
19
發行號19
DOIs
出版狀態Published - 7 10月 2019

指紋

深入研究「A multi-modal sweat sensing patch for cross-verification of sweat rate, total ionic charge, and Na+ concentration」主題。共同形成了獨特的指紋。

引用此