A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING

Liang Kai Wang; Chih Hung Lin; Yu Ting Cheng; Hsiao En Tsai; Chih Kuo Lee

A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING

Liang Kai Wang, Chih Hung Lin, Yu Ting Cheng^*, Hsiao En Tsai, Chih Kuo Lee

^*此作品的通信作者

研究成果: Conference contribution › 同行評審

摘要

The abstract presents the first molecular imprinted polymer (MIP)-based N-terminal pro-B-type natriuretic peptide (NT-proBNP) sensing electrode using LG9 peptides as the template molecule for clinical study. The MIP-based sensing electrode is an electrochemical polymerized o-phenylenediamine (o-PD) film, which can accomplish the detection in 25 min., exhibit a sensitivity of 8.24x10^-1 (ng/mL)^-1 and the limit of detection (LoD) of 14.55 pg/ml in the concentration of NT-proBNP from 0.01 to 1.25 ng/ml. and be reused over than 6 times. As compared to other sensing techniques, the presented electrode exhibits excellent characteristics including high specificity and sensitivity, short testing time, and low cost suitable for ICU applications.

原文	English
主出版物標題	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022
編輯	Reza Ghodssi, Jenna F. Chan
發行者	Transducer Research Foundation
頁面	434-435
頁數	2
ISBN（電子）	9781940470047
出版狀態	Published - 2022
事件	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022 - Hilton Head, 美國持續時間: 5 6月 2022 → 9 6月 2022

出版系列

名字	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

Conference

Conference	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022
國家/地區	美國
城市	Hilton Head
期間	5/06/22 → 9/06/22

其它文件與鏈接

Link to publication in Scopus

引用此

Wang, L. K., Lin, C. H., Cheng, Y. T., Tsai, H. E., & Lee, C. K. (2022). A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING. 於 R. Ghodssi, & J. F. Chan (編輯), 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022 (頁 434-435). (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022). Transducer Research Foundation.

Wang, Liang Kai ; Lin, Chih Hung ; Cheng, Yu Ting 等. / A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING. 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. 編輯 / Reza Ghodssi ; Jenna F. Chan. Transducer Research Foundation, 2022. 頁 434-435 (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022).

@inproceedings{a6d8c1f760e14d39a73139d0a96ada4d,

title = "A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING",

abstract = "The abstract presents the first molecular imprinted polymer (MIP)-based N-terminal pro-B-type natriuretic peptide (NT-proBNP) sensing electrode using LG9 peptides as the template molecule for clinical study. The MIP-based sensing electrode is an electrochemical polymerized o-phenylenediamine (o-PD) film, which can accomplish the detection in 25 min., exhibit a sensitivity of 8.24x10-1 (ng/mL)-1 and the limit of detection (LoD) of 14.55 pg/ml in the concentration of NT-proBNP from 0.01 to 1.25 ng/ml. and be reused over than 6 times. As compared to other sensing techniques, the presented electrode exhibits excellent characteristics including high specificity and sensitivity, short testing time, and low cost suitable for ICU applications.",

keywords = "LG-9, Molecular Imprinted Polymer, NT-proBNP, serum test",

author = "Wang, {Liang Kai} and Lin, {Chih Hung} and Cheng, {Yu Ting} and Tsai, {Hsiao En} and Lee, {Chih Kuo}",

note = "Publisher Copyright: {\textcopyright} 2022 TRF.; 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022 ; Conference date: 05-06-2022 Through 09-06-2022",

year = "2022",

language = "English",

series = "2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022",

publisher = "Transducer Research Foundation",

pages = "434--435",

editor = "Reza Ghodssi and Chan, {Jenna F.}",

booktitle = "2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022",

}

Wang, LK, Lin, CH, Cheng, YT, Tsai, HE & Lee, CK 2022, A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING. 於 R Ghodssi & JF Chan (編輯), 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022, Transducer Research Foundation, 頁 434-435, 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022, Hilton Head, 美國, 5/06/22.

A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING. / Wang, Liang Kai; Lin, Chih Hung; Cheng, Yu Ting 等.
2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. 編輯 / Reza Ghodssi; Jenna F. Chan. Transducer Research Foundation, 2022. p. 434-435 (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022).

研究成果: Conference contribution › 同行評審

TY - GEN

T1 - A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING

AU - Wang, Liang Kai

AU - Lin, Chih Hung

AU - Cheng, Yu Ting

AU - Tsai, Hsiao En

AU - Lee, Chih Kuo

PY - 2022

Y1 - 2022

N2 - The abstract presents the first molecular imprinted polymer (MIP)-based N-terminal pro-B-type natriuretic peptide (NT-proBNP) sensing electrode using LG9 peptides as the template molecule for clinical study. The MIP-based sensing electrode is an electrochemical polymerized o-phenylenediamine (o-PD) film, which can accomplish the detection in 25 min., exhibit a sensitivity of 8.24x10-1 (ng/mL)-1 and the limit of detection (LoD) of 14.55 pg/ml in the concentration of NT-proBNP from 0.01 to 1.25 ng/ml. and be reused over than 6 times. As compared to other sensing techniques, the presented electrode exhibits excellent characteristics including high specificity and sensitivity, short testing time, and low cost suitable for ICU applications.

AB - The abstract presents the first molecular imprinted polymer (MIP)-based N-terminal pro-B-type natriuretic peptide (NT-proBNP) sensing electrode using LG9 peptides as the template molecule for clinical study. The MIP-based sensing electrode is an electrochemical polymerized o-phenylenediamine (o-PD) film, which can accomplish the detection in 25 min., exhibit a sensitivity of 8.24x10-1 (ng/mL)-1 and the limit of detection (LoD) of 14.55 pg/ml in the concentration of NT-proBNP from 0.01 to 1.25 ng/ml. and be reused over than 6 times. As compared to other sensing techniques, the presented electrode exhibits excellent characteristics including high specificity and sensitivity, short testing time, and low cost suitable for ICU applications.

KW - LG-9

KW - Molecular Imprinted Polymer

KW - NT-proBNP

KW - serum test

UR - http://www.scopus.com/inward/record.url?scp=85172671100&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:85172671100

T3 - 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

SP - 434

EP - 435

BT - 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

A2 - Ghodssi, Reza

A2 - Chan, Jenna F.

PB - Transducer Research Foundation

T2 - 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

Y2 - 5 June 2022 through 9 June 2022

ER -

Wang LK, Lin CH, Cheng YT, Tsai HE, Lee CK. A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING. 於 Ghodssi R, Chan JF, 編輯, 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. Transducer Research Foundation. 2022. p. 434-435. (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022).

A MOLECULAR IMPRINTED POLYMER (MIP)-BASED NT-PROBNP SENSING ELECTRODE USING LG9 PEPTIDES FOR HEART FAILURE MONITORING

摘要

出版系列

Conference

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