A Low-Power Sensing System of VEGF Concentration with Monolithic Electrodes and An All-Digital Sub-Sampling Delay-Locked Loop

Tsung Wen Sun, Ren Wei Cheng, Tsung Heng Tsai*

*此作品的通信作者

研究成果: Conference contribution同行評審

1 引文 斯高帕斯(Scopus)

摘要

The CMOS MEMS capacitive transducer is integrated on the same chip for the point-of-care (PoC) applications. A low-noise sensing system using the sub-sampling technique to suppress the interface noise is presented. The biomarker is vascular endothelial growth factor (VEGF). The proposed sensing system converts the capacitance variations caused by the VEGF concentration at the transducer into digital codes with a low-power SAR-assisted time-to-digital converter (TDC). CMOS MEMS interdigitated electrodes are adopted as the transducer. Post-process etching and Au plating are applied on the surface of the electrodes. Experimental results show that a capacitive resolution of 28.3 fF and a sensing range of VEGF concentration from 1 to 1000 pg/ml are achieved. The power consumption of the sensing front-end is 18 μW and overall sensing system is merely 60.65 μW. The FOM of the proposed low-power VEGF sensing system is 587.8 pJ/conv.-step.

原文English
主出版物標題BioCAS 2022 - IEEE Biomedical Circuits and Systems Conference
主出版物子標題Intelligent Biomedical Systems for a Better Future, Proceedings
發行者Institute of Electrical and Electronics Engineers Inc.
頁面331-334
頁數4
ISBN(電子)9781665469173
DOIs
出版狀態Published - 2022
事件2022 IEEE Biomedical Circuits and Systems Conference, BioCAS 2022 - Taipei, Taiwan
持續時間: 13 10月 202215 10月 2022

出版系列

名字BioCAS 2022 - IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Systems for a Better Future, Proceedings

Conference

Conference2022 IEEE Biomedical Circuits and Systems Conference, BioCAS 2022
國家/地區Taiwan
城市Taipei
期間13/10/2215/10/22

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