A high-sensitivity CMOS-compatible immunosensor based on the HRP/TMB/streptavidin system

Yu Ting Tai, Yu Wei Chang, Ming Yu Lin, Yuh-Shyong Yang, Yang Tung Huang

研究成果: Conference contribution同行評審

摘要

In this report, a CMOS-compatible colorimetric biosensor based on HRP/TMB/streptavidin system is proposed. HRP activity is used for labelled target quantification by photometric detector. The modulation of light intensity due to enzyme reaction can easily be detected in 96-well microarray plate by providing 650nm light source (LED). There is good correlation between absorbance in 650nm and the concentration of HRP-streptavidin with detection limit in 1.33 pM. This device is reusable and suits for various targets by microarray plate modification rather than biochip. With the advantage of portable, low cost, and reusable, this new designed immunosensor could be widely used for both research and diagnostic purposes.

原文English
主出版物標題Proceedings of the 3rd International Conference on Sensing Technology, ICST 2008
頁面297-300
頁數4
DOIs
出版狀態Published - 1 十二月 2008
事件3rd International Conference on Sensing Technology, ICST 2008 - Tainan, Taiwan
持續時間: 30 十一月 20083 十二月 2008

出版系列

名字Proceedings of the 3rd International Conference on Sensing Technology, ICST 2008

Conference

Conference3rd International Conference on Sensing Technology, ICST 2008
國家/地區Taiwan
城市Tainan
期間30/11/083/12/08

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