A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control

Wei Ming Chen; Her-Ming Chiueh; Tsan Jieh Chen; Chia Lun Ho; Chi Jeng; Shun Ting Chang; Ming-Dou Ker; Chun Yu Lin; Ya Chun Huang; Chia Wei Chou; Tsun Yuan Fan; Ming Seng Cheng; Sheng Fu Liang; Tzu Chieh Chien; Sih Yen Wu; Yu Lin Wang; Fu Zen Shaw; Yu Hsing Huang; Chia Hsiang Yang; Jin-Chern Chiou; Chih Wei Chang; Lei Chun Chou; Chung-Yu Wu

doi:10.1109/ISSCC.2013.6487737

A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control

Wei Ming Chen^*, Her-Ming Chiueh, Tsan Jieh Chen, Chia Lun Ho, Chi Jeng, Shun Ting Chang, Ming-Dou Ker, Chun Yu Lin, Ya Chun Huang, Chia Wei Chou, Tsun Yuan Fan, Ming Seng Cheng, Sheng Fu Liang, Tzu Chieh Chien, Sih Yen Wu, Yu Lin Wang, Fu Zen Shaw, Yu Hsing Huang, Chia Hsiang Yang, Jin-Chern ChiouChih Wei Chang, Lei Chun Chou, Chung-Yu Wu

^*此作品的通信作者

研究成果: Conference contribution › 同行評審

49 引文斯高帕斯（Scopus）

摘要

Epilepsy is one of the most common neurological disorders. Around 1% of the world's population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and effective stimulation for real-time seizure control are still unavailable. In this paper, a fully integrated 8-channel closed-loop seizure-control SoC with entropy-and-spectrum- aided seizure detection and adaptive neural stimulation is presented. This chip is powered wirelessly, aiming for implantable devices. The functionality of the fabricated chip is verified in animal tests.

原文	English
主出版物標題	2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers
頁面	286-287
頁數	2
DOIs	https://doi.org/10.1109/ISSCC.2013.6487737
出版狀態	Published - 29 4月 2013
事件	2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013 - San Francisco, CA, United States 持續時間: 17 2月 2013 → 21 2月 2013

出版系列

名字	Digest of Technical Papers - IEEE International Solid-State Circuits Conference
卷	56
ISSN（列印）	0193-6530

Conference

Conference	2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013
國家/地區	United States
城市	San Francisco, CA
期間	17/02/13 → 21/02/13

存取文件

10.1109/ISSCC.2013.6487737

其它文件與鏈接

Link to publication in Scopus

引用此

Chen, W. M., Chiueh, H-M., Chen, T. J., Ho, C. L., Jeng, C., Chang, S. T., Ker, M-D., Lin, C. Y., Huang, Y. C., Chou, C. W., Fan, T. Y., Cheng, M. S., Liang, S. F., Chien, T. C., Wu, S. Y., Wang, Y. L., Shaw, F. Z., Huang, Y. H., Yang, C. H., ... Wu, C-Y. (2013). A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control. 於 2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers (頁 286-287). Article 6487737 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; 卷 56). https://doi.org/10.1109/ISSCC.2013.6487737

@inproceedings{1b878494d7cd4c0aa235ab11d8f68032,

title = "A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control",

abstract = "Epilepsy is one of the most common neurological disorders. Around 1% of the world's population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and effective stimulation for real-time seizure control are still unavailable. In this paper, a fully integrated 8-channel closed-loop seizure-control SoC with entropy-and-spectrum- aided seizure detection and adaptive neural stimulation is presented. This chip is powered wirelessly, aiming for implantable devices. The functionality of the fabricated chip is verified in animal tests.",

author = "Chen, {Wei Ming} and Her-Ming Chiueh and Chen, {Tsan Jieh} and Ho, {Chia Lun} and Chi Jeng and Chang, {Shun Ting} and Ming-Dou Ker and Lin, {Chun Yu} and Huang, {Ya Chun} and Chou, {Chia Wei} and Fan, {Tsun Yuan} and Cheng, {Ming Seng} and Liang, {Sheng Fu} and Chien, {Tzu Chieh} and Wu, {Sih Yen} and Wang, {Yu Lin} and Shaw, {Fu Zen} and Huang, {Yu Hsing} and Yang, {Chia Hsiang} and Jin-Chern Chiou and Chang, {Chih Wei} and Chou, {Lei Chun} and Chung-Yu Wu",

year = "2013",

month = apr,

day = "29",

doi = "10.1109/ISSCC.2013.6487737",

language = "English",

isbn = "9781467345132",

series = "Digest of Technical Papers - IEEE International Solid-State Circuits Conference",

pages = "286--287",

booktitle = "2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers",

note = "2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013 ; Conference date: 17-02-2013 Through 21-02-2013",

}

Chen, WM, Chiueh, H-M, Chen, TJ, Ho, CL, Jeng, C, Chang, ST, Ker, M-D, Lin, CY, Huang, YC, Chou, CW, Fan, TY, Cheng, MS, Liang, SF, Chien, TC, Wu, SY, Wang, YL, Shaw, FZ, Huang, YH, Yang, CH, Chiou, J-C, Chang, CW, Chou, LC & Wu, C-Y 2013, A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control. 於 2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers., 6487737, Digest of Technical Papers - IEEE International Solid-State Circuits Conference, 卷 56, 頁 286-287, 2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013, San Francisco, CA, United States, 17/02/13. https://doi.org/10.1109/ISSCC.2013.6487737

A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control. / Chen, Wei Ming; Chiueh, Her-Ming; Chen, Tsan Jieh 等.
2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers. 2013. p. 286-287 6487737 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; 卷 56).

研究成果: Conference contribution › 同行評審

TY - GEN

T1 - A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control

AU - Chen, Wei Ming

AU - Chiueh, Her-Ming

AU - Chen, Tsan Jieh

AU - Ho, Chia Lun

AU - Jeng, Chi

AU - Chang, Shun Ting

AU - Ker, Ming-Dou

AU - Lin, Chun Yu

AU - Huang, Ya Chun

AU - Chou, Chia Wei

AU - Fan, Tsun Yuan

AU - Cheng, Ming Seng

AU - Liang, Sheng Fu

AU - Chien, Tzu Chieh

AU - Wu, Sih Yen

AU - Wang, Yu Lin

AU - Shaw, Fu Zen

AU - Huang, Yu Hsing

AU - Yang, Chia Hsiang

AU - Chiou, Jin-Chern

AU - Chang, Chih Wei

AU - Chou, Lei Chun

AU - Wu, Chung-Yu

PY - 2013/4/29

Y1 - 2013/4/29

N2 - Epilepsy is one of the most common neurological disorders. Around 1% of the world's population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and effective stimulation for real-time seizure control are still unavailable. In this paper, a fully integrated 8-channel closed-loop seizure-control SoC with entropy-and-spectrum- aided seizure detection and adaptive neural stimulation is presented. This chip is powered wirelessly, aiming for implantable devices. The functionality of the fabricated chip is verified in animal tests.

AB - Epilepsy is one of the most common neurological disorders. Around 1% of the world's population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and effective stimulation for real-time seizure control are still unavailable. In this paper, a fully integrated 8-channel closed-loop seizure-control SoC with entropy-and-spectrum- aided seizure detection and adaptive neural stimulation is presented. This chip is powered wirelessly, aiming for implantable devices. The functionality of the fabricated chip is verified in animal tests.

UR - http://www.scopus.com/inward/record.url?scp=84876547706&partnerID=8YFLogxK

U2 - 10.1109/ISSCC.2013.6487737

DO - 10.1109/ISSCC.2013.6487737

M3 - Conference contribution

AN - SCOPUS:84876547706

SN - 9781467345132

T3 - Digest of Technical Papers - IEEE International Solid-State Circuits Conference

SP - 286

EP - 287

BT - 2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers

T2 - 2013 60th IEEE International Solid-State Circuits Conference, ISSCC 2013

Y2 - 17 February 2013 through 21 February 2013

ER -

Chen WM, Chiueh H-M, Chen TJ, Ho CL, Jeng C, Chang ST 等. A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control. 於 2013 IEEE International Solid-State Circuits Conference, ISSCC 2013 - Digest of Technical Papers. 2013. p. 286-287. 6487737. (Digest of Technical Papers - IEEE International Solid-State Circuits Conference). doi: 10.1109/ISSCC.2013.6487737

A fully integrated 8-channel closed-loop neural-prosthetic SoC for real-time epileptic seizure control

摘要

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Conference

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