TY - GEN
T1 - A Controlling Method of Nanowire Array Biosensor
AU - Lee, C. A.
AU - Watanabe, Hiroshi
PY - 2019/1/24
Y1 - 2019/1/24
N2 - The limit-of-detection (LOD) is a key factor to characterize the performance of electronic biosensing. A biosensor unit comprises plurality of nanowire biotransistors having oxide surface to bind biomolecules in a specimen electrolyte. In order to improve the LOD, we may reduce the number of bound biomolecules, which are necessary to detect signal change through nanowire transistors. However, as the number of bound biomolecules reduces, the signal change becomes too small to dominate the noise due to irregular reactions. This is the current limitation of LOD improvement. In this work, we demonstrate an exemplary concept of system solution to this problem by statistical analysis of Monte-Carlo simulation results.
AB - The limit-of-detection (LOD) is a key factor to characterize the performance of electronic biosensing. A biosensor unit comprises plurality of nanowire biotransistors having oxide surface to bind biomolecules in a specimen electrolyte. In order to improve the LOD, we may reduce the number of bound biomolecules, which are necessary to detect signal change through nanowire transistors. However, as the number of bound biomolecules reduces, the signal change becomes too small to dominate the noise due to irregular reactions. This is the current limitation of LOD improvement. In this work, we demonstrate an exemplary concept of system solution to this problem by statistical analysis of Monte-Carlo simulation results.
UR - http://www.scopus.com/inward/record.url?scp=85062302160&partnerID=8YFLogxK
U2 - 10.1109/NANO.2018.8626291
DO - 10.1109/NANO.2018.8626291
M3 - Conference contribution
AN - SCOPUS:85062302160
T3 - Proceedings of the IEEE Conference on Nanotechnology
BT - 18th International Conference on Nanotechnology, NANO 2018
PB - IEEE Computer Society
T2 - 18th International Conference on Nanotechnology, NANO 2018
Y2 - 23 July 2018 through 26 July 2018
ER -