A concise synthesis of the O-glycosylated amino acid building block; using phenyl selenoglycoside as a glycosyl donor

Weir Torn Jiaang, Meng Yang Chang, Ping Hui Tseng, Shui Tein Chen

研究成果: Article同行評審

50 引文 斯高帕斯(Scopus)

摘要

A new glycosylation methodology for synthesizing a protected TF antigen is described. The key step is to use phenyl selenoglycoside as a glycosyl donor, thereby successfully establishing O-linked Fmoc-protected threoninyl monosaccharide in an excellent yield with high α selectivity. From protected D-galactal, a protected TF antigen building block is obtained in 40% total yield.

原文English
頁(從 - 到)3127-3130
頁數4
期刊Tetrahedron Letters
41
發行號17
DOIs
出版狀態Published - 22 4月 2000

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