A 3-D capillary-endothelium-mimetic microfluidic chip for studying the extravasation behaviour of neutrophils

Tushar H. Punde*, Wen Hao Wu, Po Chen Shih, Chien Yu Fu, Tsung Pao Wang, Long Hsu, Hawn You Chang, Cheng Hsien Liu

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

Inflammation is a fundamental biology problem with daily threats to human health. In early inflammatory stage, the most important cell type involved is neutrophil, which represents the most massive leukocyte population. In this paper, we report a 3D reusable microfluidic chip which mimics the capillary endothelial lining and we have made an attempt to imitate the hemodynamic-factor in order to study the extravasation behavior of neutrophils. This microsystem is a continuous flow system which mimics the dynamic, three dimensional micro environment in the blood vessel.

原文English
主出版物標題2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
頁面2251-2254
頁數4
DOIs
出版狀態Published - 1 9月 2011
事件2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
持續時間: 5 6月 20119 6月 2011

出版系列

名字2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Conference

Conference2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
國家/地區China
城市Beijing
期間5/06/119/06/11

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