Yi-Jang Lee

2023

Rational Design of Asymmetric Polymethines to Attain NIR(II) Bioimaging at >1100 nm

Pan, H. M., Wu, C. C., Lin, C. Y., Hsu, C. S., Tsai, Y. C., Chowdhury, P., Wang, C. H., Chang, K. H., Yang, C. H., Liu, M. H., Chen, Y. C., Su, S. P., Lee, Y. J., Chiang, H. K., Chan, Y. H. & Chou, P. T., 11 1月 2023, 於: Journal of the American Chemical Society. 145, 1, p. 516-526 11 p.

研究成果: Article › 同行評審

2022

Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer

Chang, Y. C., Chang, P. M. H., Li, C. H., Chan, M. H., Lee, Y. J., Chen, M. H. & Hsiao, M., 21 1月 2022, 於: Frontiers in Oncology. 11, 811635.

研究成果: Article › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

BPR0C261, An Analogous of Microtubule Disrupting Agent D-24851 Enhances the Radiosensitivity of Human Non-Small Cell Lung Cancer Cells via p53-Dependent and p53-Independent Pathways

Leu, J. D., Lin, S. T., Chen, C. T., Chang, C. A. & Lee, Y. J., 11月 2022, 於: International Journal Of Molecular Sciences. 23, 22, 14083.

研究成果: Article › 同行評審

開啟存取

Development of Stereo NIR-II Fluorescence Imaging System for 3D Tumor Vasculature in Small Animals

Su, S. P., Lin, S-L., Chan, Y-H., Lee, Y. J., Lee, Y. C., Zeng, P. X., Li, Y. X., Yang, M-H. & Chiang, H-H., 2月 2022, 於: Biosensors. 12, 2, 85.

研究成果: Article › 同行評審

開啟存取

Evaluation of the Key Advantages between Two Modalities of Boronophenylalanine Administration for Clinical Boron Neutron Capture Therapy Using an Animal Model

Lin, Y. C., Lee, Y. J., Chen, Y. W., Wang, S. Y. & Chou, F. I., 9月 2022, 於: Cells. 11, 17, 2736.

研究成果: Article › 同行評審

開啟存取

TADF-based NIR-II semiconducting polymer dots for in vivo 3D bone imaging

Hsu, K. F., Su, S. P., Lu, H. F., Liu, M. H., Chang, Y. J., Lee, Y. J., Chiang, H. K., Hsu, C. P., Lu, C. W. & Chan, Y. H., 18 8月 2022, 於: Chemical Science. 13, 34, p. 10074-10081 8 p.

研究成果: Article › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Use of piggyBac Transposon System Constructed Murine Breast Cancer Model for Reporter Gene Imaging and Characterization of Metastatic Tumor Cells

Chen, Y. L., Wang, Y. C., Hou, K. Y., Lin, M. Y., Lin, Y. C., Chuang, H-Y. & Lee, Y. J., 2022, (Accepted/In press) 於: Journal of Medical and Biological Engineering.

研究成果: Article › 同行評審

2021

Brachytherapy approach using ¹⁷⁷Lu conjugated gold nanostars and evaluation of biodistribution, tumor retention, dosimetry and therapeutic efficacy in head and neck tumor model

Lin, M. Y., Hsieh, H. H., Chen, J-C., Chen, C-L., Sheu, N. C., Huang, W. S., Ho, S-Y., Chen, T-W., Lee, Y-J. & Wu, C-Y., 11月 2021, 於: Pharmaceutics. 13, 11, p. 1-13 13 p., 1903.

研究成果: Article › 同行評審

開啟存取

3 引文斯高帕斯（Scopus）

Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells

Leu, J. D., Wang, C. Y., Lo, C. C., Lin, M. Y., Chang, C. Y., Hung, W. C., Lin, S. T., Wang, B. S. & Lee, Y. J., 30 9月 2021, 於: Aging. 13, 18, p. 22208-22231 24 p.

研究成果: Article › 同行評審

2 引文斯高帕斯（Scopus）

Molecular Design of Ultrabright Semiconducting Polymer Dots with High NIR-II Fluorescence for 3D Tumor Mapping

Li, Y. X., Su, S. P., Yang, C. H., Liu, M. H., Lo, P. H., Chen, Y. C., Hsu, C. P., Lee, Y-J., Chiang, H-H. & Chan, Y-H., 22 9月 2021, (E-pub ahead of print) 於: Advanced Healthcare Materials. p. 1-10 10 p., 210093.

研究成果: Article › 同行評審

12 引文斯高帕斯（Scopus）

Oncomir mir-182-5p enhances radiosensitivity by inhibiting the radiation-induced antioxidant effect through sesn2 in head and neck cancer

Lin, M. Y., Chang, Y. C., Wang, S. Y., Yang, M. H., Chang, C. H., Hsiao, M., Kitsis, R. N. & Lee, Y. J., 11月 2021, 於: Antioxidants. 10, 11, 1808.

研究成果: Article › 同行評審

開啟存取

5 引文斯高帕斯（Scopus）

Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27^kip1-mediated growth delay

Tsai, C. H., Chang, C. Y., Lin, B. Z., Wu, Y. L., Wu, M. H., Lin, L. T., Huang, W. C., Holz, J. D., Sheu, T. J., Lee, J. S., Kitsis, R. N., Tai, P. H. & Lee, Y. J., 1月 2021, 於: Aging Cell. 20, 1, e13288.

研究成果: Article › 同行評審

開啟存取

4 引文斯高帕斯（Scopus）

2020

Involvement of 8-O-acetylharpagide for Ajuga taiwanensis mediated suppression of senescent phenotypes in human dermal fibroblasts

Hsu, W. H., Lin, B. Z., Leu, J. D., Lo, P. H., Yu, H. Y., Chen, C. T., Tu, Y. H., Lin, Y. L. & Lee, Y. J., 12月 2020, 於: Scientific reports. 10, 1, 19731.

研究成果: Article › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Systematic quantification of cell confluence in human normal oral fibroblasts

Chiu, C. H., Leu, J. D., Lin, T. T., Su, P. H., Li, W. C., Lee, Y. J. & Cheng, D. C., 2 12月 2020, 於: Applied Sciences (Switzerland). 10, 24, p. 1-12 12 p., 9146.

研究成果: Article › 同行評審

開啟存取

3 引文斯高帕斯（Scopus）

2019

Comparison of cofilin-1 and Twist-1 protein expression in human non-small cell lung cancer tissues

Chang, C. Y., Chang, S. L., Leu, J. D., Chang, Y. C., Hsiao, M., Lin, L. T., Lin, H. N. & Lee, Y. J., 2019, 於: Oncology Reports. 42, 2, p. 805-816 12 p.

研究成果: Article › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Evaluation of the biological behavior of a gold nanocore-encapsulated human serum albumin nanoparticle (Au@HSANP) in a CT-26 tumor/ascites mouse model after intravenous/intraperitoneal administration

Chen, C. C., Li, J. J., Guo, N. H., Chang, D. Y., Wang, C. Y., Chen, J. T., Lin, W. J., Chi, K. H., Lee, Y. J., Liu, R. S., Chen, C. L. & Wang, H. E., 1 1月 2019, 於: International Journal Of Molecular Sciences. 20, 1, 217.

研究成果: Article › 同行評審

開啟存取

11 引文斯高帕斯（Scopus）

N-dihydrogalactochitosan potentiates the radiosensitivity of liver metastatic tumor cells originated from murine breast tumors

Wang, C. Y., Chang, C. Y., Wang, C. Y., Liu, K., Kang, C. Y., Lee, Y. J. & Chen, W. R., 2 11月 2019, 於: International Journal Of Molecular Sciences. 20, 22, 5581.

研究成果: Article › 同行評審

開啟存取

5 引文斯高帕斯（Scopus）

2018

Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of SESN2

Lin, L. T., Liu, S. Y., Leu, J. D., Chang, C. Y., Chiou, S. H., Lee, T. C. & Lee, Y. J., 2018, 於: Oncotarget. 9, 22, p. 16028-16042 15 p.

研究成果: Article › 同行評審

開啟存取

13 引文斯高帕斯（Scopus）

PEGylated liposome-encapsulated rhenium-188 radiopharmaceutical inhibits proliferation and epithelial–mesenchymal transition of human head and neck cancer cells in vivo with repeated therapy

Chang, C. Y., Chen, C. C., Lin, L. T., Chang, C. H., Chen, L. C., Wang, H. E., Lee, T. W. & Lee, Y. J., 1 12月 2018, 於: Cell Death Discovery. 4, 1, 100.

研究成果: Article › 同行評審

開啟存取

16 引文斯高帕斯（Scopus）

2017

¹⁸⁸Re-liposome can induce mitochondrial autophagy and reverse drug resistance for ovarian cancer: From bench evidence to preliminary clinical proof-of-concept

Chang, C. M., Lan, K. L., Huang, W. S., Lee, Y. J., Lee, T. W., Chang, C. H. & Chuang, C. M., 5月 2017, 於: International Journal Of Molecular Sciences. 18, 5, 903.

研究成果: Article › 同行評審

開啟存取

24 引文斯高帕斯（Scopus）

Combination of radiofrequency ablation and glycated chitosan as treatment on a syngeneic breast tumor model

Chiu, H. Y., Leu, J. D., Chang, C. Y., Lee, Y. J. & Chen, W. R., 6月 2017, 於: Anticancer Research. 37, 6, p. 2965-2974 10 p.

研究成果: Article › 同行評審

開啟存取

5 引文斯高帕斯（Scopus）

2016

Antimicrobial properties of an immunomodulator - 15 kDa human granulysin

Wei, H. M., Lin, L. C., Wang, C. F., Lee, Y. J., Chen, Y. T. & Liao, Y. D., 1 6月 2016, 於: PLoS ONE. 11, 6, e0156321.

研究成果: Article › 同行評審

開啟存取

21 引文斯高帕斯（Scopus）

Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models

Leu, J. D., Wang, B. S., Chiu, S. J., Chang, C. Y., Chen, C. C., Chen, F. D., Avirmed, S. & Lee, Y. J., 12月 2016, 於: Oncology Letters. 12, 6, p. 4975-4982 8 p.

研究成果: Article › 同行評審

開啟存取

11 引文斯高帕斯（Scopus）

Intraperitoneal ¹⁸⁸Re-Liposome delivery switches ovarian cancer metabolism from glycolysis to oxidative phosphorylation and effectively controls ovarian tumour growth in mice

Shen, Y. A., Lan, K. L., Chang, C. H., Lin, L. T., He, C. L., Chen, P. H., Lee, T. W., Lee, Y. J. & Chuang, C. M., 1 5月 2016, 於: Radiotherapy and Oncology. 119, 2, p. 282-290 9 p.

研究成果: Article › 同行評審

14 引文斯高帕斯（Scopus）

Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model

Lin, L. T., Chang, C. Y., Chang, C. H., Wang, H. E., Chiou, S. H., Liu, R. S., Lee, T. W. & Lee, Y. J., 2016, 於: Oncotarget. 7, 40, p. 65782-65796 15 p.

研究成果: Article › 同行評審

開啟存取

20 引文斯高帕斯（Scopus）

Synthesis, surface modification, and photophysical studies of Ln₂O₂S:Ln'³⁺ (Ln=Gd, Tb, Eu; Ln'=Tb and/ or Eu) nanoparticles for luminescence bioimaging

Lin, S. L., Liu, T. Y., Lo, C. L., Wang, B. S., Lee, Y. J., Lin, K. Y. & Chang, C. A., 1 7月 2016, 於: Journal of Luminescence. 175, p. 165-175 11 p.

研究成果: Article › 同行評審

14 引文斯高帕斯（Scopus）

2015

Low-fluence rate, long duration photodynamic therapy in glioma mouse model using organic light emitting diode (OLED)

Guo, H. W., Lin, L. T., Chen, P. H., Ho, M. H., Huang, W. T., Lee, Y. J., Chiou, S. H., Hsieh, Y. S., Dong, C. Y. & Wang, H. W., 1 9月 2015, 於: Photodiagnosis and Photodynamic Therapy. 12, 3, p. 504-510 7 p.

研究成果: Article › 同行評審

35 引文斯高帕斯（Scopus）

Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA

Tsai, C. H., Lin, L. T., Wang, C. Y., Chiu, Y. W., Chou, Y. T., Chiu, S. J., Wang, H. E., Liu, R. S., Wu, C. Y., Chan, P. C., Yang, M. H., Chiou, S. H., Liao, M. J. & Lee, Y. J., 1 5月 2015, 於: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 5, p. 851-861 11 p.

研究成果: Article › 同行評審

開啟存取

35 引文斯高帕斯（Scopus）

2014

Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells

Huang, Y. H., Yang, P. M., Chuah, Q. Y., Lee, Y. J., Hsieh, Y. F., Peng, C. W. & Chiu, S. J., 7月 2014, 於: Autophagy. 10, 7, p. 1212-1228 17 p.

研究成果: Article › 同行評審

開啟存取

49 引文斯高帕斯（Scopus）

Determination of urine cofilin-1 level in acute kidney injury using a high-throughput localized surface plasmon-coupled fluorescence biosensor

Chang, Y. F., Chao, C. H., Lin, L. Y., Tsai, C. H., Chou, C. & Lee, Y. J., 1 1月 2014, 於: Journal of Biomedical Optics. 19, 1, p. 11004 1 p.

研究成果: Article › 同行評審

6 引文斯高帕斯（Scopus）

Evaluation of the therapeutic and diagnostic effects of PEGylated liposome-embedded 188re on human non-small cell lung cancer using an orthotopic small-animal model

Lin, L. T., Chang, C. H., Yu, H. L., Liu, R. S., Wang, H. E., Chiu, S. J., Chen, F. D., Lee, T. W. & Lee, Y. J., 1 11月 2014, 於: Journal of Nuclear Medicine. 55, 11, p. 1864-1870 7 p.

研究成果: Article › 同行評審

開啟存取

26 引文斯高帕斯（Scopus）

Radiation induces senescence and a bystander effect through metabolic alterations.

Liao, E. C., Hsu, Y. T., Chuah, Q. Y., Lee, Y. J., Hu, J. Y., Huang, T. C., Yang, P. M. & Chiu, S. J., 2014, 於: Cell Death and Disease. 5

研究成果: Article › 同行評審

開啟存取

66 引文斯高帕斯（Scopus）

Synergistic effects of glycated chitosan with high-intensity focused ultrasound on suppression of metastases in a syngeneic breast tumor model

Chen, Y. L., Wang, C. Y., Yang, F. Y., Wang, B. S., Chen, J. Y., Lin, L. T., Leu, J. D., Chiu, S. J., Chen, F. D., Lee, Y. J. & Chen, W. R., 4月 2014, 於: Cell Death and Disease. 5, 4, e1178.

研究成果: Article › 同行評審

開啟存取

28 引文斯高帕斯（Scopus）

2013

A Comparative Study of Primary and Recurrent Human Glioblastoma Multiforme Using the Small Animal Imaging and Molecular Expressive Profiles

Lin, L. T., Chiou, S. H., Lee, T. W., Liu, R. S., Hwang, J. J., Chang, C. H., Ma, H. I. & Lee, Y. J., 6月 2013, 於: Molecular Imaging and Biology. 15, 3, p. 262-272 11 p.

研究成果: Article › 同行評審

8 引文斯高帕斯（Scopus）

Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity

Leu, J. D., Chiu, Y. W., Lo, C. C., Chiang, P. H., Chiu, S. J., Tsai, C. H., Hwang, J. J., Chen, R. C., Gorbunova, V. & Lee, Y. J., 6月 2013, 於: International Journal of Radiation Biology. 89, 6, p. 433-444 12 p.

研究成果: Article › 同行評審

4 引文斯高帕斯（Scopus）

MPlum-IFP 1.4 fluorescent fusion protein may display förster resonance energy transfer associated properties that can be used for near-infrared based reporter gene imaging

Lin, L. T., Wang, B. S., Chen, J. C., Liu, C. H., Chou, C., Chiu, S. J., Chang, W. Y., Liu, R. S., Allen Chang, C. & Lee, Y. J., 12月 2013, 於: Journal of Biomedical Optics. 18, 12, 126013.

研究成果: Article › 同行評審

5 引文斯高帕斯（Scopus）

Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways

Yu, Y. C., Yang, P. M., Chuah, Q. Y., Huang, Y. H., Peng, C. W., Lee, Y. J. & Chiu, S. J., 2013, 於: Scientific reports. 3, 1675.

研究成果: Article › 同行評審

開啟存取

47 引文斯高帕斯（Scopus）

Simultaneous imaging of temporal changes of NF-κB activity and viable tumor cells in Huh7/NF-κB-tk-luc2/rfp tumor-bearing mice

Wang, W. H., Chiang, I. T., Liu, Y. C., Hsu, F. T., Chen, H. W., Chen, C-L., Lee, Y-J., Lin, W. J. & Hwang, J-J., 5月 2013, 於: In Vivo. 27, 3, p. 339-350 12 p.

研究成果: Article › 同行評審

6 引文斯高帕斯（Scopus）

2012

Detection of urine cofilin-1 from patients hospitalized in the intensive care unit using the metal-enhanced fluorescence technique

Chao, C. H., Chang, Y. F., Chen, H. C., Lin, L. Y., Yu, P. C., Chang, Y. S., Lee, Y. J. & Chou, C., 10月 2012, 於: Sensors and Actuators, B: Chemical. 173, p. 184-190 7 p.

研究成果: Article › 同行評審

10 引文斯高帕斯（Scopus）

Remnant living cells that escape cell loss in late-stage tumors exhibit cancer stem cell-like characteristics

Chen, Y. L., Wang, S. Y., Liu, R. S., Wang, H. E., Chen, J. C., Chiou, S. H., Chang, C. A., Lin, L. T., Tan, D. T. W. & Lee, Y. J., 10月 2012, 於: Cell Death and Disease. 3, 10, e399.

研究成果: Article › 同行評審

開啟存取

9 引文斯高帕斯（Scopus）

Targeting protective autophagy exacerbates UV-triggered apoptotic cell death

Chen, L. H., Chu, P. M., Lee, Y. J., Tu, P. H., Chi, C. W., Lee, H. C. & Chiou, S. H., 1月 2012, 於: International Journal Of Molecular Sciences. 13, 1, p. 1209-1224 16 p.

研究成果: Article › 同行評審

開啟存取

37 引文斯高帕斯（Scopus）

TIMP2 deficient mice develop accelerated osteoarthritis via promotion of angiogenesis upon destabilization of the medial meniscus

Mi, M., Shi, S., Li, T., Holz, J., Lee, Y. J., Sheu, T. J., Liao, Q. & Xiao, T., 29 6月 2012, 於: Biochemical and Biophysical Research Communications. 423, 2, p. 366-372 7 p.

研究成果: Article › 同行評審

21 引文斯高帕斯（Scopus）

2011

Antiproliferative effects of N-heterocyclic indolyl glyoxylamide derivatives on human lung cancer cells

Huang, T. H., Chiu, S. J., Chiang, P. H., Chiou, S. H., Li, W. T., Chen, C. T., Chang, C. A., Chen, J. C. & Lee, Y. J., 10月 2011, 於: Anticancer Research. 31, 10, p. 3407-3415 9 p.

研究成果: Article › 同行評審

9 引文斯高帕斯（Scopus）

Association of platelet-derived growth factor receptor β accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells

Liu, S. Y., Lee, Y. J. & Lee, T. C., 23 6月 2011, 於: FEBS Letters. 585, 12, p. 1853-1858 6 p.

研究成果: Article › 同行評審

開啟存取

21 引文斯高帕斯（Scopus）

Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway

Chen, L. H., Loong, C. C., Su, T. L., Lee, Y. J., Chu, P. M., Tsai, M. L., Tsai, P. H., Tu, P. H., Chi, C. W., Lee, H. C. & Chiou, S. H., 1 3月 2011, 於: Biochemical Pharmacology. 81, 5, p. 594-605 12 p.

研究成果: Article › 同行評審

39 引文斯高帕斯（Scopus）

Discrimination of breast cancer by measuring prostate-specific antigen levels in women's serum

Chang, Y. F., Hung, S. H., Lee, Y. J., Chen, R. C., Su, L. C., Lai, C. S. & Chou, C., 1 7月 2011, 於: Analytical chemistry. 83, 13, p. 5324-5328 5 p.

研究成果: Article › 同行評審

42 引文斯高帕斯（Scopus）

Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response

Chu, P. M., Chiou, S. H., Su, T. L., Lee, Y. J., Chen, L. H., Chen, Y. W., Yen, S. H., Chen, M. T., Chen, M. H., Shih, Y. H., Tu, P. H. & Ma, H. I., 19 1月 2011, 於: Radiation Oncology. 6, 1, 7.

研究成果: Article › 同行評審

開啟存取

18 引文斯高帕斯（Scopus）

Involvement of p53 R72P polymorphism in the association of MDM2-SNP309 with breast cancer

Leu, J. D., Wang, C. Y., Tsai, H. Y., Lin, I. F., Chen, R. C. & Lee, Y. J., 6月 2011, 於: Oncology Reports. 25, 6, p. 1755-1763 9 p.

研究成果: Article › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

2010

Depletion of Securin Induces Senescence After Irradiation and Enhances Radiosensitivity in Human Cancer Cells Regardless of Functional p53 Expression

Chen, W. S., Yu, Y. C., Lee, Y. J., Chen, J. H., Hsu, H. Y. & Chiu, S. J., 1 6月 2010, 於: International Journal of Radiation Oncology Biology Physics. 77, 2, p. 566-574 9 p.

研究成果: Article › 同行評審

26 引文斯高帕斯（Scopus）

Detection of prostate-specific antigen with a paired surface plasma wave biosensor

Su, L. C., Chen, R. C., Li, Y. C., Chang, Y. F., Lee, Y. J., Lee, C. C. & Chou, C., 1 5月 2010, 於: Analytical chemistry. 82, 9, p. 3714-3718 5 p.

研究成果: Article › 同行評審

14 引文斯高帕斯（Scopus）

李 易展

研究成果

搜尋結果

李易展