Ta-Hsien Lin

2025

Growth inhibition and toxicity assessments of cis-3,4-diaryl-α-methylene-γ-butyrolactams in cultured human renal cancer cells and zebrafish embryos

Lee, A. S. Y., Lin, T. H., Liu, Y. Y., Wang, Y. H., Cheng, S. C., Li, T. S., Sun, C. Y. & Chen, Y. H., 3月 2025, 於: Biochimica et Biophysica Acta - General Subjects. 1869, 3, 130761.

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2024

Applications of three-dimensional whey protein amyloid fibril-based hybrid aerogels in oil/water separation and emulsion separation

Tu, J. L., Lai, Y. R., Lin, C. Y., Wang, S. S. S. & Lin, T. H., 12月 2024, 於: International Journal of Biological Macromolecules. 283, 137680.

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Development of two-dimensional amyloid fibril/carboxymethyl cellulose hybrid membranes for effective adsorption of hexavalent chromium

Lai, Y. R., Hou, X. X., How, S. C., Lin, T. H. & Wang, S. S. S., 12月 2024, 於: Journal of Environmental Chemical Engineering. 12, 6, 114134.

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2 引文斯高帕斯（Scopus）

Disulfiram inhibits coronaviral main protease by conjugating to its substrate entry site

Kuan, Y., Chu, H. F., Hsu, P. H., Hsu, K. C., Lin, T. H., Huang, C. H. & Chen, W. Y., 9月 2024, 於: International Journal of Biological Macromolecules. 276, 133955.

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Encapsulation with a complex of acidic/alkaline polysaccharide-whey protein isolate fibril bilayer microcapsules enhances the stability of β-carotene under acidic environments

Yang, Y. Y., Lai, Y. R., How, S. C., Lin, T. H. & Wang, S. S. S., 7月 2024, 於: Journal of the Taiwan Institute of Chemical Engineers. 160, 105344.

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2 引文斯高帕斯（Scopus）

Using silver nanoparticle-decorated whey protein isolate amyloid fibrils to modify the electrode surface used for electrochemical detection of para-nitrophenol

Lai, Y. R., Wang, S. S. S. & Lin, T. H., 4月 2024, 於: International Journal of Biological Macromolecules. 264, 130404.

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9 引文斯高帕斯（Scopus）

Using titanium dioxide nanoparticle-deposited whey protein isolate amyloid fibrils to photocatalyze the degradation of methylene blue

Lai, Y. R., Huang, C. F., How, S. C., Lin, T. H. & Wang, S. S. S., 7月 2024, 於: Journal of the Taiwan Institute of Chemical Engineers. 160, 105313.

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7 引文斯高帕斯（Scopus）

2023

Application of Amyloid-Based Hybrid Membranes in Drug Delivery

Lai, Y. R., Wang, S. S. S., Hsu, T. L., Chou, S. H., How, S. C. & Lin, T. H., 3月 2023, 於: Polymers. 15, 6, 1444.

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16 引文斯高帕斯（Scopus）

Developing targeted drug delivery carriers for breast cancer using glutathione-sensitive doxorubicin-coupled glycated bovine serum albumin nanoparticles

Hsu, W. H., Ku, C. L., Lai, Y. R., Wang, S. S. S., Chou, S. H. & Lin, T. H., 30 9月 2023, 於: International Journal of Biological Macromolecules. 249, 126114.

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8 引文斯高帕斯（Scopus）

2022

Insights to Human γD-Crystallin Unfolding by NMR Spectroscopy and Molecular Dynamics Simulations

Hsueh, S. S., Wang, S. S. S., Chen, S. H., Wang, C. L., Wu, J. W. & Lin, T. H., 1 2月 2022, 於: International Journal Of Molecular Sciences. 23, 3, 1591.

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2 引文斯高帕斯（Scopus）

Silver nanoparticle-deposited whey protein isolate amyloid fibrils as catalysts for the reduction of methylene blue

Lai, Y. R., Lai, J. T., Wang, S. S. S., Kuo, Y. C. & Lin, T. H., 31 7月 2022, 於: International Journal of Biological Macromolecules. 213, p. 1098-1114 17 p.

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23 引文斯高帕斯（Scopus）

Structural and Biochemical Characterization of Porcine Epidemic Diarrhea Virus Papain-Like Protease 2

Chu, H. F., Cheng, S. C., Sun, C. Y., Chou, C. Y., Lin, T.-H. & Chen, W. Y., 1月 2022, 於: Journal of Virology. 96, 1, e01372-21.

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5 引文斯高帕斯（Scopus）

2021

Characterization of Androgen Receptor Complex Associated Protein (ARCAP) in hepatocellular carcinoma and liver

Chang, T. J., Hsia, C. Y., Chau, G. Y., Hsiao, L. T., Huang, K. T., King, K. L., Lui, W. Y., Li, A. F. Y., Wang, C. L., Tsai, P. H., Chien, Y. & Lin, T. H., 1 12月 2021, 於: Journal of the Chinese Medical Association. 84, 12, p. 1100-1108 9 p.

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4 引文斯高帕斯（Scopus）

Disulfiram and 6-Thioguanine synergistically inhibit the enzymatic activities of USP2 and USP21

Lin, H. C., Kuan, Y., Chu, H. F., Cheng, S. C., Pan, H. C., Chen, W. Y., Sun, C. Y. & Lin, T. H., 15 4月 2021, 於: International Journal of Biological Macromolecules. 176, p. 490-497 8 p.

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19 引文斯高帕斯（Scopus）

Examining the effect of bovine serum albumin on the properties and drug release behavior of β-lactoglobulin-derived amyloid fibril-based hydrogels

How, S. C., Lin, T. H., Chang, C. C. & Wang, S. S. S., 1 8月 2021, 於: International Journal of Biological Macromolecules. 184, p. 79-91 13 p.

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26 引文斯高帕斯（Scopus）

Protection of human γD-crystallin protein from ultraviolet C-induced aggregation by ortho-vanillin

Hsueh, S. S., Lu, J. H., Wu, J. W., Lin, T. H. & Wang, S. S. S., 15 11月 2021, 於: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 261, 120023.

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6 引文斯高帕斯（Scopus）

USP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer

Huang, Y. T., Cheng, A. C., Tang, H. C., Huang, G. C., Cai, L., Lin, T. H., Wu, K. J., Tseng, P. H., Wang, G. G. & Chen, W. Y., 10月 2021, 於: Cell Death and Disease. 12, 10, 880.

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26 引文斯高帕斯（Scopus）

2020

Conformational characterization of native and L17A/F19A-substituted dutch-typeβ-amyloid peptides

He, K. C., Chen, Y. R., Liang, C. T., Huang, S. J., Tzeng, C. Y., Chang, C. F., Huang, S. J., Huang, H. B. & Lin, T. H., 1 4月 2020, 於: International Journal Of Molecular Sciences. 21, 7, 2571.

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6 引文斯高帕斯（Scopus）

Genomic analysis and comparative multiple sequences of SARS-CoV2

Chang, T. J., Yang, D. M., Wang, M. L., Liang, K. H., Tsai, P. H., Chiou, S. H., Lin, T. H. & Wang, C. T., 6月 2020, 於: Journal of the Chinese Medical Association. 83, 6, p. 537-543 7 p.

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33 引文斯高帕斯（Scopus）

Genomic variance of Open Reading Frames (ORFs) and Spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Tsai, P. H., Wang, M. L., Yang, D. M., Liang, K. H., Chou, S. J., Chiou, S. H., Lin, T. H., Wang, C. T. & Chang, T. J., 8月 2020, 於: Journal of the Chinese Medical Association. 83, 8, p. 725-732 8 p.

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27 引文斯高帕斯（Scopus）

Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4

Lin, Y. S., Huang, K. Y., Yu, H. C., Lu, M. C., Fan, C. J., Huang Tseng, H. Y., Jhuang, B. Y., Liu, S. Q., Lai, N. S., Lin, T. H. & Huang, H. B., 15 10月 2020, 於: Biochemical and Biophysical Research Communications. 531, 2, p. 236-241 6 p.

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1 引文斯高帕斯（Scopus）

2018

Characterization of the interactions between inhibitor-1 and recombinant PP1 by NMR spectroscopy

Liang, C. T., Lin, Y. S., Huang, Y. C., Huang, H. L., Yang, J. Q., Wu, T. H., Chang, C. F., Huang, S. J., Huang, H. B. & Lin, T. H., 1 12月 2018, 於: Scientific reports. 8, 1, 50.

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2 引文斯高帕斯（Scopus）

Exploring the effects of methylene blue on amyloid fibrillogenesis of lysozyme

How, S. C., Cheng, Y. H., Lo, C. H., Lai, J. T., Lin, T. H., Bednarikova, Z., Antosova, A., Gazova, Z., Wu, J. W. & Wang, S. S. S., 11月 2018, 於: International Journal of Biological Macromolecules. 119, p. 1059-1067 9 p.

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26 引文斯高帕斯（Scopus）

2017

Investigating the effects of erythrosine B on amyloid fibril formation derived from lysozyme

Kuo, C. T., Chen, Y. L., Hsu, W. T., How, S. C., Cheng, Y. H., Hsueh, S. S., Liu, H. S., Lin, T. H., Wu, J. W. & Wang, S. S. S., 1 5月 2017, 於: International Journal of Biological Macromolecules. 98, p. 159-168 10 p.

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23 引文斯高帕斯（Scopus）

2016

L17A/F19A substitutions augment the α-helicity of β-amyloid peptide discordant segment

Liang, C. T., Huang, H. B., Wang, C. C., Chen, Y. R., Chang, C. F., Shiao, M. S., Chen, Y. G. & Lin, T. H., 4月 2016, 於: PLoS ONE. 11, 4, e0154327.

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9 引文斯高帕斯（Scopus）

2015

Investigating the effects of plasma pretreatment on the formation of ordered aggregates of lysozyme

Chang, C. K., Chen, W. A., Sie, C. Y., Lin, S. C., Lin, L. T. W., Lin, T. H., Hsu, C. C. & Wang, S. S. S., 1 2月 2015, 於: Colloids and Surfaces B: Biointerfaces. 126, 1, p. 154-161 8 p.

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6 引文斯高帕斯（Scopus）

Resonance assignments and secondary structure of a phytocystatin from Sesamum indicum

Hu, Y. J., Irene, D., Lo, C. J., Cai, Y. L., Tzen, T. C., Lin, T. H. & Chyan, C. L., 22 10月 2015, 於: Biomolecular NMR Assignments. 9, 2, p. 309-311 3 p.

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9 引文斯高帕斯（Scopus）

Resonance assignments and secondary structure of apolipoprotein E C-terminal domain in DHPC micelles

Lo, C. J., Chyan, C. L., Chen, Y. C., Chang, C. F., Huang, H. B. & Lin, T. H., 4月 2015, 於: Biomolecular NMR Assignments. 9, 1, p. 187-190 4 p.

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The Arctic mutation accelerates Aβ aggregation in SDS through reducing the helical propensity of residues 15-25

Lo, C. J., Wang, C. C., Huang, H. B., Chang, C. F., Shiao, M. S., Chen, Y. C. & Lin, T. H., 1 3月 2015, 於: Amyloid. 22, 1, p. 8-18 11 p.

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9 引文斯高帕斯（Scopus）

2014

Effect of C-terminal residues of Aβ on copper binding affinity, structural conversion and aggregation

Huang, S. H., Ke, S. C., Lin, T. H., Huang, H. B. & Chen, Y. C., 3 3月 2014, 於: PLoS ONE. 9, 3, e90385.

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10 引文斯高帕斯（Scopus）

Identification of the high molecular weight isoform of phostensin

Lin, Y. S., Huang, H. L., Liu, W. T., Lin, T. H. & Huang, H. B., 15 1月 2014, 於: International Journal Of Molecular Sciences. 15, 1, p. 1068-1079 12 p.

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6 引文斯高帕斯（Scopus）

Resonance assignments and secondary structure of calmodulin in complex with its target sequence in rat olfactory cyclic nucleotide-gated ion channel

Irene, D., Sung, F. H., Huang, J. W., Lin, T. H., Chen, Y. C. & Chyan, C. L., 4月 2014, 於: Biomolecular NMR Assignments. 8, 1, p. 97-102 6 p.

研究成果: Article › 同行評審

2013

Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel

Irene, D., Huang, J. W., Chung, T. Y., Li, F. Y., Tzen, J. T. C., Lin, T. H. & Chyan, C. L., 2013, 於: Journal of Biomolecular Structure and Dynamics. 31, 4, p. 414-425 12 p.

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9 引文斯高帕斯（Scopus）

Effect of Alanine Replacement of L17 and F19 on the Aggregation and Neurotoxicity of Arctic-Type Aβ₄₀

Chen, Y. R., Huang, H. B., Lo, C. J., Wang, C. C., Ho, L. K., Liu, H. T., Shiao, M. S., Lin, T. H. & Chen, Y. C., 25 4月 2013, 於: PLoS ONE. 8, 4, e61874.

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9 引文斯高帕斯（Scopus）

Examining the inhibitory actions of copolypeptides against amyloid fibrillogenesis of bovine insulin

Kao, C. Y., Lai, J. K., Lin, T. H., Lin, Y. J., Jan, J. S. & Wang, S. S. S., 5 9月 2013, 於: Biochemical Engineering Journal. 78, p. 181-188 8 p.

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1 引文斯高帕斯（Scopus）

2012

Characterization of Aβ aggregation mechanism probed by congo red

Wang, C. C., Huang, H. B., Tsay, H. J., Shiao, M. S., Wu, W. J. W., Cheng, Y. C. & Lin, T. H., 2012, 於: Journal of Biomolecular Structure and Dynamics. 30, 2, p. 160-169 10 p.

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14 引文斯高帕斯（Scopus）

Identification and characterization of the actin-binding motif of Phostensin

Wang, T. F., Lai, N. S., Huang, K. Y., Huang, H. L., Lu, M. C., Lin, Y. S., Chen, C. Y., Liu, S. Q., Lin, T. H. & Huang, H. B., 12月 2012, 於: International Journal Of Molecular Sciences. 13, 12, p. 15967-15982 16 p.

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9 引文斯高帕斯（Scopus）

2011

Asp159 is a critical core amino acid of an IgE-binding and cross-reactive epitope of a dust mite allergen Der f 7

Chou, H., Tam, M. F., Lee, S. S., Tang, R. B., Lin, T. H., Tai, H. Y., Chen, Y. S. & Shen, H. D., 9月 2011, 於: Molecular Immunology. 48, 15-16, p. 2130-2134 5 p.

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25 引文斯高帕斯（Scopus）

Aβ40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aβ40

Chen, Y. R., Huang, H. B., Lo, C. J., Wang, C. C., Su, C. L., Liu, H. T., Shiao, M. S., Lin, T. H. & Chen, Y. C., 4 2月 2011, 於: Biochemical and Biophysical Research Communications. 405, 1, p. 91-95 5 p.

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12 引文斯高帕斯（Scopus）

Correlation of copper interaction, copper-driven aggregation, and copper-driven H₂O₂ formation with Aβ40 conformation

Lin, T. H., Yang, C. A., Chen, Y. H., Ke, S. C., Chen, Y. R., Huang, H. B. & Chen, Y. C., 2011, 於: International Journal of Alzheimer's Disease. 607861.

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10 引文斯高帕斯（Scopus）

2010

FLJ23654 encodes a heart protein phosphatase 1-binding protein (Hepp1)

Chen, C. Y., Lai, N. S., Yang, J. J., Huang, H. L., Hung, W. C., Li, C., Lin, T. H. & Huang, H. B., 1 1月 2010, 於: Biochemical and Biophysical Research Communications. 391, 1, p. 698-702 5 p.

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6 引文斯高帕斯（Scopus）

The effect of PKA-phosphorylation on the structure of inhibitor-1 studied by NMR spectroscopy

Huang, Y. C., Chen, Y. C., Tsay, H. J., Chyan, C. L., Chen, C. Y., Huang, H. B. & Lin, T. H., 2月 2010, 於: Journal of Biochemistry. 147, 2, p. 273-278 6 p.

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7 引文斯高帕斯（Scopus）

2009

Phostensin caps to the pointed end of actin filaments and modulates actin dynamics

Lai, N. S., Wang, T. F., Wang, S. L., Chen, C. Y., Yen, J. Y., Huang, H. L., Li, C., Huang, K. Y., Liu, S. Q., Lin, T. H. & Huang, H. B., 2 10月 2009, 於: Biochemical and Biophysical Research Communications. 387, 4, p. 676-681 6 p.

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21 引文斯高帕斯（Scopus）

2007

Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit

Kao, S. C., Chen, C. Y., Wang, S. L., Yang, J. J., Hung, W. C., Chen, Y. C., Lai, N. S., Liu, H. T., Huang, H. L., Chen, H. C., Lin, T. H. & Huang, H. B., 11 5月 2007, 於: Biochemical and Biophysical Research Communications. 356, 3, p. 594-598 5 p.

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33 引文斯高帕斯（Scopus）

Structural and biochemical characterization of inhibitor-1α

Huang, H. B., Chen, Y. C., Lee, T. T., Huang, Y. C., Liu, H. T., Liu, C. K., Tsay, H. J. & Lin, T. H., 15 8月 2007, 於: Proteins: Structure, Function and Genetics. 68, 3, p. 779-788 10 p.

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7 引文斯高帕斯（Scopus）

The correlation between neurotoxicity, aggregative ability and secondary structure studied by sequence truncated Aβ peptides

Liao, M. Q., Tzeng, Y. J., Chang, L. Y. X., Huang, H. B., Lin, T. H., Chyan, C. L. & Chen, Y. C., 20 3月 2007, 於: FEBS Letters. 581, 6, p. 1161-1165 5 p.

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77 引文斯高帕斯（Scopus）

2006

The effect of Aβ conformation on the metal affinity and aggregation mechanism studied by circular dichroism spectroscopy

Chen, Y. R., Huang, H. B., Chyan, C. L., Shiao, M. S., Lin, T. H. & Chen, Y. C., 4月 2006, 於: Journal of Biochemistry. 139, 4, p. 733-740 8 p.

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51 引文斯高帕斯（Scopus）

2005

Characterization of the protein phosphatase 1-binding motifs of inhibitor-2 and DARPP-32 by surface plasmon resonance

Lin, T. H., Tsai, P. C., Liu, H. T., Chen, Y. C., Wang, L. H., Hsieh, F. K. & Huang, H. B., 12月 2005, 於: Journal of Biochemistry. 138, 6, p. 697-700 4 p.

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6 引文斯高帕斯（Scopus）

Purification, crystallization and preliminary crystallographic studies of a calmodulin-OLFp hybrid molecule

Chyan, C. L., Huang, P. C., Lin, T. H., Huang, J. W., Lin, S. S., Huang, H. B. & Chen, Y. C., 8月 2005, 於: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 61, 8, p. 785-787 3 p.

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3 引文斯高帕斯（Scopus）

Structural variation in human apolipoprotein E3 and E4: Secondary structure, tertiary structure, and size distribution

Chou, C. Y., Lin, Y. L., Huang, Y. C., Sheu, S. Y., Lin, T. H., Tsay, H. J., Chang, G. G. & Shiao, M. S., 1月 2005, 於: Biophysical Journal. 88, 1, p. 455-466 12 p.

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43 引文斯高帕斯（Scopus）

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