每年研究成果
每年研究成果
- 1個結果中的 - 50105
搜尋結果
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2025
Fatty acid binding protein 3 activates endothelial adhesion of circulating monocytes and impairs endothelial angiogenesis
Wu, Y. W., Chen, J. W., Tsai, H. Y., Leu, H. B., Chang, C. C. & Chang, T. T., 2025, (Accepted/In press) 於: British Journal of Pharmacology.研究成果: Article › 同行評審
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2024
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation
Chang, T. T., Lin, L. Y., Chen, C. & Chen, J. W., 8月 2024, 於: Angiogenesis. 27, 3, p. 475-499 25 p.研究成果: Article › 同行評審
開啟存取3 引文 斯高帕斯（Scopus） -
CXCL5 inhibition ameliorates acute kidney injury and prevents the progression from acute kidney injury to chronic kidney disease
Chang, T. T., Li, S. Y., Tsai, M. T., Chiang, C. H., Chen, C. & Chen, J. W., 11月 2024, 於: Clinical Science. 138, 22, p. 1451-1466 16 p.研究成果: Article › 同行評審
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CXCL5 inhibition improves kidney function by protecting renal tubular epithelial cells in diabetic kidney disease
Chen, C., Lin, L. Y., Wu, Y. W., Chen, J. W. & Chang, T. T., 11月 2024, 於: Clinical Immunology. 268, 110369.研究成果: Article › 同行評審
1 引文 斯高帕斯（Scopus） -
Diosgenin Reduces Acute Kidney Injury and Ameliorates the Progression to Chronic Kidney Disease by Modifying the NOX4/p65 Signaling Pathways
Chiang, C. H., Lan, T. Y., Hsieh, J. H., Lin, S. C., Chen, J. W. & Chang, T. T., 7 8月 2024, 於: Journal of Agricultural and Food Chemistry. 72, 31, p. 17444-17454 11 p.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Inhibition of Adipocyte-Derived FABP4 Reduces Adipocyte Inflammation, Improves Angiogenesis, and Facilitates Wound Healing in Metabolic Dysfunctions
Wu, Y. W., Chen, J. W., Tsai, H. Y., Huang, J. H., Chang, C. C. & Chang, T. T., 4月 2025, 於: Journal of Investigative Dermatology. 145, 4, p. 939-953 15 p.研究成果: Article › 同行評審
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Inhibition of CCL7 improves endothelial dysfunction and vasculopathy in mouse models of diabetes mellitus
Chang, T. T., Li, Y. Z., Mo, H. W., Chen, C., Lin, L. Y., Chang, C. C. & Chen, J. W., 4 9月 2024, 於: Science Translational Medicine. 16, 763, eadn1507.研究成果: Article › 同行評審
1 引文 斯高帕斯（Scopus） -
Novel prognostic impact and cell specific role of endocan in patients with coronary artery disease
Lin, L. Y., Chang, T. T., Leu, H. B., Huang, C. C., Wu, T. C., Chou, R. H., Huang, P. H., Yin, W. H., Tseng, W. K., Wu, Y. W., Lin, T. H., Yeh, H. I., Chang, K. C., Wang, J. H., Wu, C. C. & Chen, J. W., 2024, (Accepted/In press) 於: Clinical Research in Cardiology.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Soluble tumor necrosis factor receptor type 1 is an alternative marker of urinary albumin-creatinine ratio and estimated glomerular filtration rate for predicting the decline of renal function in subjects with type 2 diabetes mellitus
Chang, L. H., Chang, T. T., Chu, C. H., Huang, C. C. & Lin, L. Y., 15 5月 2024, 於: Clinica Chimica Acta. 558, 117880.研究成果: Article › 同行評審
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Vagus nerve stimulation inhibits cortical spreading depression via glutamate-dependent TrkB activation mechanism in the nucleus tractus solitarius
Liu, T. T., Chen, S. P., Wang, S. J. & Yen, J. C., 2月 2024, 於: Cephalalgia. 44, 2研究成果: Article › 同行評審
開啟存取5 引文 斯高帕斯（Scopus） -
2023
CXCL5 suppression recovers neovascularization and accelerates wound healing in diabetes mellitus
Chen, C., Lin, L. Y., Chen, J. W. & Chang, T. T., 12月 2023, 於: Cardiovascular Diabetology. 22, 1, 172.研究成果: Article › 同行評審
開啟存取12 引文 斯高帕斯（Scopus） -
GMI, a fungal immunomodulatory protein, ameliorates SARS-CoV-2 envelope protein-induced inflammation in macrophages via inhibition of MAPK pathway
Lin, Z. H., Yeh, H., Lo, H. C., Hua, W. J., Ni, M. Y., Wang, L. K., Chang, T. T., Yang, M. H. & Lin, T. Y., 30 6月 2023, 於: International Journal of Biological Macromolecules. 241, 124648.研究成果: Article › 同行評審
開啟存取6 引文 斯高帕斯（Scopus） -
High-density lipoprotein protects vascular endothelial cells from indoxyl sulfate insults through its antioxidant ability
Chen, C., Chang, C. C., Lee, I. T., Huang, C. Y., Lin, F. Y., Lin, S. J., Chen, J. W. & Chang, T. T., 2023, 於: Cell Cycle. 22, 21-22, p. 2409-2423 15 p.研究成果: Article › 同行評審
4 引文 斯高帕斯（Scopus） -
Macrophage inflammatory protein-1β as a novel therapeutic target for renal protection in diabetic kidney disease
Chang, T. T., Li, S. Y., Lin, L. Y., Chen, C. & Chen, J. W., 5月 2023, 於: Biomedicine and Pharmacotherapy. 161, 114450.研究成果: Article › 同行評審
開啟存取3 引文 斯高帕斯（Scopus） -
Neuronal NLRP3 inflammasome mediates spreading depolarization-evoked trigeminovascular activation
Chen, P. Y., Yen, J. C., Liu, T. T., Chen, S. T., Wang, S. J. & Chen, S. P., 1 7月 2023, 於: Brain. 146, 7, p. 2989-3002 14 p.研究成果: Article › 同行評審
22 引文 斯高帕斯（Scopus） -
Repurposing Astragalus Polysaccharide PG2 for Inhibiting ACE2 and SARS-CoV-2 Spike Syncytial Formation and Anti-Inflammatory Effects
Lee, C. Y., Nguyen, A. T., Doan, L. H., Chu, L. W., Chang, C. H., Liu, H. K., Lee, I. L., Wang, T. H., Lai, J. M., Tsao, S. M., Liao, H. J., Ping, Y. H. & Huang, C. Y. F., 3月 2023, 於: Viruses. 15, 3, 641.研究成果: Article › 同行評審
開啟存取7 引文 斯高帕斯（Scopus） -
Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease
Chiang, C. H., Chen, C., Fang, S. Y., Lin, S. C., Chen, J. W. & Chang, T. T., 15 8月 2023, 於: Life Sciences. 327, 121863.研究成果: Article › 同行評審
7 引文 斯高帕斯（Scopus） -
2022
A Houttuynia cordata–based Chinese herbal formula improved symptoms of allergic rhinitis during the COVID-19 pandemic
Chang, K. W., Lin, T. Y., Fu, S. L., Ping, Y. H., Chen, F. P. & Kung, Y. Y., 1 6月 2022, 於: Journal of the Chinese Medical Association. 85, 6, p. 717-722 6 p.研究成果: Article › 同行評審
開啟存取12 引文 斯高帕斯（Scopus） -
Antioxidation and Nrf2-mediated heme oxygenase-1 activation contribute to renal protective effects of hydralazine in diabetic nephropathy
Chang, T. T., Chiang, C. H., Chen, C., Lin, S. C., Lee, H. J. & Chen, J. W., 7月 2022, 於: Biomedicine and Pharmacotherapy. 151, 113139.研究成果: Article › 同行評審
開啟存取11 引文 斯高帕斯（Scopus） -
CCL4 Deletion Accelerates Wound Healing by Improving Endothelial Cell Functions in Diabetes Mellitus
Chang, T. T., Chen, C., Lin, L. Y. & Chen, J. W., 8月 2022, 於: Biomedicines. 10, 8, 1963.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Development of Fluorescence-Tagged SARS-CoV-2 Virus-like Particles by a Tri-Cistronic Vector Expression System for Investigating the Cellular Entry of SARS-CoV-2
Chang, Y. S., Chu, L. W., Chen, Z. Y., Wu, J. S., Su, W. C., Yang, C. J., Ping, Y. H. & Lin, C. W., 12月 2022, 於: Viruses. 14, 12, 2825.研究成果: Article › 同行評審
開啟存取9 引文 斯高帕斯（Scopus） -
Effect of heated tobacco products and traditional cigarettes on pulmonary toxicity and SARS-CoV-2-induced lung injury
Tsou, H. H., Wang, P. H., Ting, T. H., Ping, Y. H., Liu, T. Y., Cheng, H. W. & Wang, H. T., 9月 2022, 於: Toxicology. 479, 153318.研究成果: Article › 同行評審
開啟存取3 引文 斯高帕斯（Scopus） -
Efficacy profile of noninvasive vagus nerve stimulation on cortical spreading depression susceptibility and the tissue response in a rat model
Liu, T. T., Morais, A., Takizawa, T., Mulder, I., Simon, B. J., Chen, S. P., Wang, S. J., Ayata, C. & Yen, J. C., 12月 2022, 於: Journal of Headache and Pain. 23, 1, 12.研究成果: Article › 同行評審
開啟存取16 引文 斯高帕斯（Scopus） -
Glycosylation and S-palmitoylation regulate SARS-CoV-2 spike protein intracellular trafficking
Tien, C. F., Tsai, W. T., Chen, C. H., Chou, H. J., Zhang, M. M., Lin, J. J., Lin, E. J., Dai, S. S., Ping, Y. H., Yu, C. Y., Kuo, Y. P., Tsai, W. H., Chen, H. W. & Yu, G. Y., 19 8月 2022, 於: iScience. 25, 8, 104709.研究成果: Article › 同行評審
開啟存取20 引文 斯高帕斯（Scopus） -
Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro
Yeh, Y. C., Doan, L. H., Huang, Z. Y., Chu, L. W., Shi, T. H., Lee, Y. R., Wu, C. T., Lin, C. H., Chiang, S. T., Liu, H. K., Chuang, T. H., Ping, Y. H., Liu, H. S. & Huang, C. Y. F., 25 3月 2022, 於: Frontiers in Pharmacology. 12, 765553.研究成果: Article › 同行評審
開啟存取47 引文 斯高帕斯（Scopus） -
Midostaurin Modulates Tumor Microenvironment and Enhances Efficacy of Anti-PD-1 against Colon Cancer
Lai, C. T., Chi, C. W., Wu, S. H., Shieh, H. R., Yen, J. C. & Chen, Y. J., 10月 2022, 於: Cancers. 14, 19, 4847.研究成果: Article › 同行評審
開啟存取11 引文 斯高帕斯（Scopus） -
Potential Impacts of Hydralazine as a Novel Antioxidant on Cardiovascular and Renal Disease—Beyond Vasodilation and Blood Pressure Lowering
Chang, T. T. & Chen, J. W., 11月 2022, 於: Antioxidants. 11, 11, 2224.研究成果: Article › 同行評審
開啟存取6 引文 斯高帕斯（Scopus） -
The Traditional Chinese Medicine Formula Jing Guan Fang for Preventing SARS-CoV-2 Infection: From Clinical Observation to Basic Research
Ping, Y. H., Yeh, H., Chu, L. W., Lin, Z. H., Hsu, Y. C., Lin, L. C., Hsu, C. H., Fu, S. L. & Lin, T. Y., 21 3月 2022, 於: Frontiers in Pharmacology. 13, 744439.研究成果: Article › 同行評審
開啟存取18 引文 斯高帕斯（Scopus） -
Virofree, an Herbal Medicine-Based Formula, Interrupts the Viral Infection of Delta and Omicron Variants of SARS-CoV-2
Doan, L. H., Chu, L. W., Huang, Z. Y., Nguyen, A. T., Lee, C. Y., Huang, C. L., Chang, Y. F., Hsieh, W. Y., Nguyen, T. T. H., Lin, C. H., Su, C. L., Chuang, T. H., Lai, J. M., Wang, F. S., Yang, C. J., Liu, H. K., Ping, Y. H. & Huang, C. Y. F., 4 7月 2022, 於: Frontiers in Pharmacology. 13, 905197.研究成果: Article › 同行評審
開啟存取10 引文 斯高帕斯（Scopus） -
2021
Direct CCL4 inhibition modulates gut microbiota, reduces circulating trimethylamine N-oxide, and improves glucose and lipid metabolism in high-fat-diet-induced diabetes mellitus
Chang, T. T. & Chen, J. W., 2021, 於: Journal of Inflammation Research. 14, p. 6237-6250 14 p.研究成果: Article › 同行評審
開啟存取23 引文 斯高帕斯（Scopus） -
Inhibition on CXCL5 reduces aortic matrix metalloproteinase 9 expression and protects against acute aortic dissection
Chang, T. T., Liao, L. Y. & Chen, J. W., 12月 2021, 於: Vascular Pharmacology. 141, 106926.研究成果: Article › 同行評審
13 引文 斯高帕斯（Scopus） -
In situ slow-release recombinant growth differentiation factor 11 exhibits therapeutic efficacy in ischemic stroke
Su, H. H., Yen, J. C., Liao, J. M., Wang, Y. H., Liu, P. H., MacDonald, I. J., Tsai, C. F., Chen, Y. H. & Huang, S. S., 12月 2021, 於: Biomedicine and Pharmacotherapy. 144, 112290.研究成果: Article › 同行評審
開啟存取6 引文 斯高帕斯（Scopus） -
2020
Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections
Chen, W. C., Simanjuntak, Y., Chu, L. W., Ping, Y. H., Lee, Y. L., Lin, Y. L. & Li, W. S., 13 2月 2020, 於: Journal of Medicinal Chemistry. 63, 3, p. 1313-1327 15 p.研究成果: Article › 同行評審
30 引文 斯高帕斯（Scopus） -
CCL4 inhibition in atherosclerosis: Effects on plaque stability, endothelial cell adhesiveness, and macrophages activation
Chang, T. T., Yang, H. Y., Chen, C. & Chen, J. W., 2 9月 2020, 於: International Journal Of Molecular Sciences. 21, 18, p. 1-19 19 p., 6567.研究成果: Article › 同行評審
開啟存取36 引文 斯高帕斯（Scopus） -
Fatty‐acid‐binding protein 4 as a novel contributor to mononuclear cell activation and endothelial cell dysfunction in atherosclerosis
Wu, Y. W., Chang, T. T., Chang, C. C. & Chen, J. W., 1 12月 2020, 於: International Journal Of Molecular Sciences. 21, 23, p. 1-16 16 p., 9245.研究成果: Article › 同行評審
開啟存取29 引文 斯高帕斯（Scopus） -
Mevalonate pathway enzyme HMGCS1 contributes to gastric cancer progression
Wang, I. H., Huang, T. T., Chen, J. L., Chu, L. W., Ping, Y. H., Hsu, K. W., Huang, K. H., Fang, W. L., Lee, H. C., Chen, C. F., Liao, C. C., Hsieh, R. H. & Yeh, T. S., 5月 2020, 於: Cancers. 12, 5, 1088.研究成果: Article › 同行評審
開啟存取30 引文 斯高帕斯（Scopus） -
One-step reverse transcription quantitative pcr assay for simultaneous detection of chikungunya, dengue and zika virus blood sample spotted on filter paper
Mejia, M. F. A., Lin, S. H., Shu, P. Y., Ping, Y. H. & Ji, D. D., 11月 2020, 於: Southeast Asian Journal of Tropical Medicine and Public Health. 51, 6, p. 886-895 10 p.研究成果: Article › 同行評審
1 引文 斯高帕斯（Scopus） -
The efficacy of first-line tyrosine kinase inhibitors combined with co-medications in Asian patients with EGFR mutation non-small cell lung cancer
Su, V. Y. F., Yang, K. Y., Huang, T. Y., Hsu, C. C., Chen, Y. M., Yen, J. C., Chou, Y. C., Chang, Y. L. & He, C. H., 1 12月 2020, 於: Scientific reports. 10, 1, 14965.研究成果: Article › 同行評審
開啟存取23 引文 斯高帕斯（Scopus） -
The Mechanism of the Zika Virus Crossing the Placental Barrier and the Blood-Brain Barrier
Chiu, C. F., Chu, L. W., Liao, I. C., Simanjuntak, Y., Lin, Y. L., Juan, C. C. & Ping, Y. H., 20 2月 2020, 於: Frontiers in Microbiology. 11, 214.研究成果: Article › 同行評審
開啟存取88 引文 斯高帕斯（Scopus） -
Vagus nerve stimulation inhibits cortical spreading depression exclusively through central mechanisms
Morais, A., Liu, T. T., Qin, T., Sadhegian, H., Ay, I., Yagmur, D., Mendes Da Silva, R., Chung, D., Simon, B., Guedes, R., Chen, S. P., Wang, S. J., Yen, J. C. & Ayata, C., 7月 2020, 於: Pain. 161, 7, p. 1661-1669 9 p.研究成果: Article › 同行評審
開啟存取42 引文 斯高帕斯（Scopus） -
2019
Caffeine does not affect susceptibility to cortical spreading depolarization in mice
Yalcin, N., Chen, S. P., Yu, E. S., Liu, T. T., Yen, J. C., Atalay, Y. B., Qin, T., Celik, F., van den Maagdenberg, A. M. J. M., Moskowitz, M. A., Ayata, C. & Eikermann-Haerter, K., 1 4月 2019, 於: Journal of Cerebral Blood Flow and Metabolism. 39, 4, p. 740-750 11 p.研究成果: Article › 同行評審
開啟存取9 引文 斯高帕斯（Scopus） -
Exogenous GDF11 attenuates non-canonical TGF-β signaling to protect the heart from acute myocardial ischemia–reperfusion injury
Su, H. H., Liao, J. M., Wang, Y. H., Chen, K. M., Lin, C. W., Lee, I. H., Li, Y. J., Huang, J. Y., Tsai, S. K., Yen, J. C. & Huang, S. S., 1 5月 2019, 於: Basic Research in Cardiology. 114, 3, 20.研究成果: Article › 同行評審
56 引文 斯高帕斯（Scopus） -
Inhibition of macrophage inflammatory protein-1β improves endothelial progenitor cell function and ischemia-induced angiogenesis in diabetes
Chang, T. T., Lin, L. Y. & Chen, J. W., 15 2月 2019, 於: Angiogenesis. 22, 1, p. 53-65 13 p.研究成果: Article › 同行評審
17 引文 斯高帕斯（Scopus） -
TIM-1 as a signal receptor triggers dengue virus-induced autophagy
Chu, L. W., Yang, C. J., Peng, K. J., Chen, P. L., Wang, S. J. & Ping, Y. H., 1 10月 2019, 於: International Journal Of Molecular Sciences. 20, 19, 4893.研究成果: Article › 同行評審
開啟存取22 引文 斯高帕斯（Scopus） -
2018
Microrna-23a/27a/24-2 cluster promotes gastric cancer cell proliferation synergistically
Hua, K., Chen, Y. T., Chen, C. F., Tang, Y. S., Huang, T. T., Lin, Y. C., Yeh, T. S., Huang, K. H., Lee, H. C., Hsu, M. T., Chi, C. W., Wu, C. W., Lin, C. H. & Ping, Y. H., 8月 2018, 於: Oncology Letters. 16, 2, p. 2319-2325 7 p.研究成果: Article › 同行評審
開啟存取24 引文 斯高帕斯（Scopus） -
Proton pump inhibitors use is associated with a lower risk of acute exacerbation and mortality in patients with coexistent COPD and GERD
Su, V. Y. F., Liao, H. F., Perng, D. W., Chou, Y. C., Hsu, C. C., Chou, C. L., Chang, Y. L., Yen, J. C., Chen, T. J. & Chou, T. C., 2018, 於: International Journal of COPD. 13, p. 2907-2915 9 p.研究成果: Article › 同行評審
開啟存取10 引文 斯高帕斯（Scopus） -
2017
Energy utilization of induced pluripotent stem cell-derived cardiomyocyte in Fabry disease
Chou, S. J., Yu, W. C., Chang, Y. L., Chen, W. Y., Chang, W. C., Chien, Y., Yen, J. C., Liu, Y. Y., Chen, S. J., Wang, C. Y., Chen, Y. H., Niu, D. M., Lin, S. J., Chen, J. W., Chiou, S. H. & Leu, H. B., 1 4月 2017, 於: International Journal of Cardiology. 232, p. 255-263 9 p.研究成果: Article › 同行評審
34 引文 斯高帕斯（Scopus） -
Identification of novel cancer fusion genes using chromosome breakpoint screening
Hua, K., Lin, C. H., Chen, Y. L., Lin, C. H., Ping, Y. H., Jou, Y. S. & Chen, C. F., 4月 2017, 於: Oncology Reports. 37, 4, p. 2101-2108 8 p.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation
Chen, J. L., Ping, Y. H., Tseng, M. J., Chang, Y. I., Lee, H. C., Hsieh, R. H. & Yeh, T. S., 21 2月 2017, 於: Scientific reports. 7, 42883.研究成果: Article › 同行評審
開啟存取10 引文 斯高帕斯（Scopus） -
Phellinus linteus mycelium alleviates myocardial ischemia-reperfusion injury through autophagic regulation
Su, H. H., Chu, Y. C., Liao, J. M., Wang, Y. H., Jan, M. S., Lin, C. W., Wu, C. Y., Tseng, C. Y., Yen, J. C. & Huang, S. S., 4 4月 2017, 於: Frontiers in Pharmacology. 8, APR, 175.研究成果: Article › 同行評審
開啟存取24 引文 斯高帕斯（Scopus）