醫學系高齡醫學科

2024

Activin A as a potential biomarker for preserved ratio impaired spirometry (PRISm) and clinical outcomes in community-dwelling adults

Sun, C. Y., Lee, W. J., Shen, H. C., Yu, W. K., Chen, W. C., Chen, H. M., Hsiao, F. Y., Yang, K. Y. & Chen, L. K., 11月 2024, 於: Archives of Gerontology and Geriatrics. 126, 105539.

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Advancing nutrition risk assessment in middle-aged and older individuals with diverse food cultures: A data-driven personalized approach to predict incident hypertension, diabetes and mortality

Guan, S. T., Lai, H. Y., Chen, L. K. & Hsiao, F. Y., 2月 2024, 於: Journal of Nutrition, Health and Aging. 28, 2, 100025.

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1 引文斯高帕斯（Scopus）

Altered cerebellar and caudate gray-matter volumes and structural covariance networks preceding dual cognitive and mobility impairments in older people

Lee, P. L., Chou, K. H., Lee, W. J., Peng, L. N., Chen, L. K., Lin, C. P., Liang, C. K. & Chung, C. P., 4月 2024, 於: Alzheimer's and Dementia. 20, 4, p. 2420-2433 14 p.

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2 引文斯高帕斯（Scopus）

Association between changes in potentially inappropriate medication use and adverse outcomes during hospitalization in older adults: A retrospective study

Hsu, Y. H., Chou, M. Y., Chang, W. C., Chen, M. T., Wang, Y. C., Liao, M. C., Liang, C. K., Chen, L. K. & Lin, Y. T., 1月 2024, 於: Archives of Gerontology and Geriatrics. 116, 105139.

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Association between possible sarcopenia and domain-specific cognitive impairment in middle-aged and older adults: Insights from the Gan-Dau Healthy Longevity Plan

Lin, Y. C., Chen, Z. J., Tung, H. H., Ye, Y. J., Lai, H. Y., Hsiao, F. Y. & Chen, L. K., 9月 2024, 於: Experimental Gerontology. 194, 112487.

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1 引文斯高帕斯（Scopus）

Concomitant use of antidepressants and benzodiazepines during pregnancy and associated risk of congenital malformations: a population-based cohort study in Taiwan

Chuang, H. M., Meng, L. C., Lin, C. W., Chen, W. W., Chen, Y. Y., Shang, C. Y., Chen, L. K. & Hsiao, F. Y., 8月 2024, 於: The Lancet Psychiatry. 11, 8, p. 601-610 10 p.

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1 引文斯高帕斯（Scopus）

Dissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters

Cheng, H. M., Wang, J. J., Chuang, S. Y., Lin, C. H., Mitchell, G. F., Huang, C. J., Wang, P. N., Chung, C. P., Chen, L. K., Pan, W. H., Peng, L. N. & Chen, C. H., 2024, (Accepted/In press) 於: Hypertension Research.

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2 引文斯高帕斯（Scopus）

Dose-Responsive Impacts of Social Frailty on Intrinsic Capacity and Healthy Aging among Community-Dwelling Middle-aged and Older Adults: Stronger Roles of Social Determinants over Biomarkers

Huang, S. T., Lu, W. H., Lee, W. J., Peng, L. N., Chen, L. K. & Hsiao, F. Y., 2月 2024, 於: The Journal of frailty & aging. 13, 2, p. 139-148 10 p.

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Enhancing Intrinsic Capacity and Related Biomarkers in Community-Dwelling Multimorbid Older Adults Through Integrated Multidomain Interventions: Ancillary Findings From the Taiwan Integrated Geriatric (TIGER) Trial

Lee, W. J., Peng, L. N., Lin, M. H., Kim, S., Hsiao, F. Y. & Chen, L. K., 5月 2024, 於: Journal of the American Medical Directors Association. 25, 5, p. 757-763.e4

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6 引文斯高帕斯（Scopus）

Follistatin-respiratory connection predicting all-cause mortality among community-dwelling middle-to-old age individuals: Results from the I-Lan Longitudinal Study

Shen, H. C., Lee, W. J., Sun, C. Y., Yu, W. K., Chen, W. C., Hsiao, F. Y., Yang, K. Y. & Chen, L. K., 8月 2024, 於: Journal of Nutrition, Health and Aging. 28, 8, 100285.

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Intrinsic capacity and multimorbidity predicting incident disability–Insights from the I-Lan Longitudinal Aging Study

Lee, W. J., Peng, L. N., Lin, M. H., Loh, C. H., Hsiao, F. Y. & Chen, L. K., 6月 2024, 於: Archives of Gerontology and Geriatrics. 121, 105357.

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7 引文斯高帕斯（Scopus）

Prescription Patterns and Predisposing Factors of Benzodiazepine and Z-Hypnotic Use During Pregnancy: A Nationwide Cohort Study

Meng, L. C., Lin, C. W., Chuang, H. M., Chen, Y. Y., Shang, C. Y., Wu, C. Y., Chen, L. K. & Hsiao, F. Y., 6月 2024, 於: Pharmacoepidemiology and Drug Safety. 33, 6, e5847.

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Protein-enriched soup and weekly exercise improve muscle health: A randomized trial in mid-to-old age with inadequate protein intake

Peng, L. N., Lin, M. H., Tseng, S. H., Yen, K. H., Lee, H. F., Hsiao, F. Y. & Chen, L. K., 8月 2024, 於: Journal of Cachexia, Sarcopenia and Muscle. 15, 4, p. 1348-1357 10 p.

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1 引文斯高帕斯（Scopus）

Recurrence of Diabetic Foot Complications: A Domino Effect Leading to Lethal Consequences—Insights From a National Longitudinal Study

Hsu, C. C., Lai, H. Y., Lin, H. Y., Pan, S. C., Cheng, N. C., Chen, L. K., Hsiao, F. Y. & Lin, S. W., 1 6月 2024, 於: Open Forum Infectious Diseases. 11, 6, ofae276.

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Roles of Baseline Intrinsic Capacity and its Subdomains on the Overall Efficacy of Multidomain Intervention in Promoting Healthy Aging among Community-Dwelling Older Adults: Analysis from a Nationwide Cluster-Randomized Controlled Trial

Liang, C. K., Lee, W. J., Chou, M. Y., Hwang, A. C., Lin, C. S., Peng, L. N., Hsiao, F. Y., Loh, C. H. & Chen, L. K., 3月 2024, 於: The journal of prevention of Alzheimer's disease. 11, 2, p. 356-365 10 p.

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6 引文斯高帕斯（Scopus）

Safeguarding vitality and cognition: The role of sarcopenia in intrinsic capacity decline among octogenarians from multiple cohorts

Hsu, P. S., Lee, W. J., Peng, L. N., Lu, W. H., Meng, L. C., Hsiao, F. Y. & Chen, L. K., 6月 2024, 於: Journal of Nutrition, Health and Aging. 28, 6, 100268.

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1 引文斯高帕斯（Scopus）

Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort

Lu, Y. W., Chang, C. C., Chou, R. H., Lee, W. J., Chen, L. K., Huang, P. H. & Lin, S. J., 12月 2024, 於: BMC Geriatrics. 24, 1, 182.

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1 引文斯高帕斯（Scopus）

Sex-specific implications of inflammation in covert cerebral small vessel disease

Chen, B. A., Lee, W. J., Meng, L. C., Lin, Y. C., Chung, C. P., Hsiao, F. Y. & Chen, L. K., 12月 2024, 於: BMC Neurology. 24, 1, 220.

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The burden of frailty in heart failure: Prevalence, impacts on clinical outcomes and the role of heart failure medications

Lai, H. Y., Huang, S. T., Anker, S. D., von Haehling, S., Akishita, M., Arai, H., Chen, L. K. & Hsiao, F. Y., 4月 2024, 於: Journal of Cachexia, Sarcopenia and Muscle. 15, 2, p. 660-670 11 p.

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3 引文斯高帕斯（Scopus）

The distinct impacts of sarcopenic and dynapenic obesity on mortality in middle-aged and older adults based on different adiposity metrics: Results from I-Lan Longitudinal Aging Study

Tseng, L. Y., Liang, C. K., Peng, L. N., Lin, M. H., Loh, C. H., Lee, W. J., Hsiao, F. Y. & Chen, L. K., 8月 2024, 於: Clinical Nutrition. 43, 8, p. 1892-1899 8 p.

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1 引文斯高帕斯（Scopus）

The Impact of Social Vulnerability on Alcohol Consumption and Mortality: A 20-year Age, Sex-stratified Analysis from the Taiwan Longitudinal Study of Aging

Weng, T. L., Meng, L. C., Peng, L. N., Lin, M. H., Hsiao, F. Y. & Chen, L. K., 7月 2024, 於: Journal of the American Medical Directors Association. 25, 7, 105008.

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Trends in dementia incidence and mortality, and dynamic changes in comorbidity and healthcare utilization from 2004 to 2017: A Taiwan national cohort study

Huang, S. T., Loh, C. H., Lin, C. H., Hsiao, F. Y. & Chen, L. K., 6月 2024, 於: Archives of Gerontology and Geriatrics. 121, 105330.

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6 引文斯高帕斯（Scopus）

Unveiling the multifaceted nexus of subjective aging, biological aging, and chronological age: Findings from a nationally representative cohort study

Lin, Y. C., Lin, H. Y., Chen, L. K. & Hsiao, F. Y., 2月 2024, 於: Archives of Gerontology and Geriatrics. 117, 105164.

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5 引文斯高帕斯（Scopus）

2023

Advanced brain age in community-dwelling population with combined physical and cognitive impairments

Kuo, C. Y., Lee, P. L., Peng, L. N., Lee, W. J., Wang, P. N., Chen, L. K., Chou, K. H., Chung, C. P. & Lin, C. P., 10月 2023, 於: Neurobiology of Aging. 130, p. 114-123 10 p.

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5 引文斯高帕斯（Scopus）

Age- and Sex-Different Associations between Cognitive Performance and Inflammatory Biomarkers in Community Dwelling Older Adults: towards Precision Preventive Strategies

Chen, B. A., Lee, W. J., Chung, C. P., Peng, L. N. & Chen, L. K., 1月 2023, 於: The journal of prevention of Alzheimer's disease. 10, 1, p. 104-111 8 p.

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A novel online training programme for healthcare professionals caring for older adults

Michel, J. P., Ecarnot, F., Arai, H. & Chen, L. K., 8月 2023, 於: Aging clinical and experimental research. 35, 8, p. 1763-1769 7 p.

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3 引文斯高帕斯（Scopus）

Anti-tumor necrosis factor-α is potentially better than tumor necrosis factor-α as the biomarker for sarcopenia: Results from the I-Lan longitudinal aging study

Lin, W. J., Lee, W. J., Peng, L. N., Huang, Y. L., Tung, C. Y., Lin, C. H., Tsai, T. F. & Chen, L. K., 2月 2023, 於: Experimental Gerontology. 172, 112053.

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3 引文斯高帕斯（Scopus）

Association between masseter muscle volume, nutritional status, and cognitive status in older people

Lin, C. S., Liu, L. K., Chen, L. K. & Fuh, J. L., 10月 2023, 於: Archives of Gerontology and Geriatrics. 113, 105038.

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3 引文斯高帕斯（Scopus）

Association between maternal benzodiazepine or Z-hypnotic use in early pregnancy and the risk of stillbirth, preterm birth, and small for gestational age: a nationwide, population-based cohort study in Taiwan

Meng, L. C., Lin, C. W., Lin, Y. C., Huang, S. T., Chen, Y. Y., Shang, C. Y., Wu, C. Y., Chen, L. K., Chan, K. A. & Hsiao, F. Y., 7月 2023, 於: The Lancet Psychiatry. 10, 7, p. 499-508 10 p.

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8 引文斯高帕斯（Scopus）

Cardiovascular Disease Risk Burden, Cognitive Impairments and Incident Dementia among Community-Dwelling Middle-Aged and Older Adults: An 8-Year Longitudinal Follow-up Study

Lee, Y. H., Lee, W. J., Peng, L. N., Lin, M. H., Hsiao, F. Y. & Chen, L. K., 8月 2023, 於: Journal of Nutrition, Health and Aging. 27, 8, p. 641-648 8 p.

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3 引文斯高帕斯（Scopus）

Clinical impacts of frailty on 123,172 people with diabetes mellitus considering the age of onset and drugs of choice: A nationwide population-based 10-year trajectory analysis

Huang, S. T., Chen, L. K. & Hsiao, F. Y., 7月 2023, 於: Age and Ageing. 52, 7, afad128.

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10 引文斯高帕斯（Scopus）

Clinical practice for sarcopenia in Asia: Online survey by the Asian Working Group for Sarcopenia

Yamada, M., Lee, W. J., Akishita, M., Yang, M., Kang, L., Kim, S., Lim, J. P., Lim, W. S., Merchant, R. A., Ong, T., Peng, L. N., Phannarus, H., Tan, M. P., Tay, L., Won, C. W., Woo, J., Chen, L. K. & Arai, H., 12月 2023, 於: Archives of Gerontology and Geriatrics. 115, 105132.

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11 引文斯高帕斯（Scopus）

Comparative Analysis of Intrinsic Capacity Impairments, Determinants, and Clinical Consequences in Older Community-Dwellers in Japan and Taiwan: Longitudinal Studies Showing Shared Traits and Distinct Presentations

Zhang, S., Peng, L. N., Otsuka, R., Liang, C. K., Nishita, Y., Arai, H. & Chen, L. K., 11月 2023, 於: Journal of Nutrition, Health and Aging. 27, 11, p. 1038-1046 9 p.

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5 引文斯高帕斯（Scopus）

Health care utilization and potentially preventable adverse outcomes of high-need, high-cost middle-aged and older adults: Needs for integrated care models with life-course approach

Meng, L. C., Huang, S. T., Chen, H. M., Hashmi, A. Z., Hsiao, F. Y. & Chen, L. K., 6月 2023, 於: Archives of Gerontology and Geriatrics. 109, 104956.

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15 引文斯高帕斯（Scopus）

Intrinsic capacity differs from functional ability in predicting 10-year mortality and biological features in healthy aging: results from the I-Lan longitudinal aging study

Lee, W. J., Peng, L. N., Lin, M. H., Loh, C. H., Hsiao, F. Y. & Chen, L. K., 2023, 於: Aging. 15, 3, p. 748-764 17 p.

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14 引文斯高帕斯（Scopus）

Longitudinal impact of distinct infection trajectories on all-cause mortality of older people in Taiwan: a retrospective, nationwide, population-based study

Lin, H. Y., Hsiao, F. Y., Huang, S. T., Chen, Y. C., Lin, S. W. & Chen, L. K., 9月 2023, 於: The Lancet Healthy Longevity. 4, 9, p. e508-e516

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4 引文斯高帕斯（Scopus）

Long-Term Mortality Risk in Older Adults with Sarcopenia: An 11-Year Prospective Cohort Study Comparing AWGS 2014 and AWGS 2019 Guidelines for Enhanced Clinical Utility and Accurate Risk Prediction

Liang, C. K., Peng, L. N., Lin, M. H., Loh, C. H., Lee, W. J., Hsiao, F. Y. & Chen, L. K., 7月 2023, 於: Journal of Nutrition, Health and Aging. 27, 7, p. 507-513 7 p.

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9 引文斯高帕斯（Scopus）

Medication overload: A closer look at polypharmacy and potentially inappropriate medications among older people in Taiwan and Japan

Meng, L. C., Kojima, T., Suzuki, Y., Weng, S. E., Chen, H. M., Huang, S. T., Akishita, M., Chen, L. K. & Hsiao, F. Y., 12月 2023, 於: Archives of Gerontology and Geriatrics. 115, 105100.

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7 引文斯高帕斯（Scopus）

Sebacic Acid as a Potential Age-Related Biomarker of Liver Aging: Evidence Linking Mice and Human

Huang, C. H., Lee, W. J., Huang, Y. L., Tsai, T. F., Chen, L. K. & Lin, C. H., 1 10月 2023, 於: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 78, 10, p. 1799-1808 10 p.

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2 引文斯高帕斯（Scopus）

Sex-specific impacts of social isolation on loneliness, depressive symptoms, cognitive impairment, and biomarkers: Results from the social environment and biomarker of aging study

Hsiao, F. Y., Peng, L. N., Lee, W. J. & Chen, L. K., 3月 2023, 於: Archives of Gerontology and Geriatrics. 106, 104872.

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14 引文斯高帕斯（Scopus）

The association of potentially inappropriate medications, polypharmacy and anticholinergic burden with readmission and emergency room revisit after discharge: A hospital-based retrospective cohort study

Liang, C. K., Chou, M. Y., Hsu, Y. H., Wang, Y. C., Liao, M. C., Chen, M. T., Hsiao, P. Y., Chen, L. K. & Lin, Y. T., 1月 2023, 於: British Journal of Clinical Pharmacology. 89, 1, p. 187-200 14 p.

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6 引文斯高帕斯（Scopus）

Timed Up and Go test and gastrointestinal disorders among hospitalized older adults with fall risk

Chou, S. J., Tung, H. H., Peng, L.-N. & Chen, L. K., 4月 2023, 於: Archives of Gerontology and Geriatrics. 107, 104918.

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2 引文斯高帕斯（Scopus）

Transitions in Frailty and 4-Year Mortality Risk in Taiwan Longitudinal Study on Aging

Hwang, A. C., Chen, L. Y., Tang, T. C., Peng, L. N., Lin, M. H., Chou, Y. J., Hsiao, F. Y. & Chen, L. K., 1月 2023, 於: Journal of the American Medical Directors Association. 24, 1, p. 48-56.e5

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7 引文斯高帕斯（Scopus）

Untangling the Complex Interplay between Social Isolation, Anorexia, Sarcopenia, and Mortality: Insights from a Longitudinal Study

Lin, H. Y., Lin, Y. C., Chen, L. K. & Hsiao, F. Y., 10月 2023, 於: Journal of Nutrition, Health and Aging. 27, 10, p. 797-805 9 p.

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9 引文斯高帕斯（Scopus）

Using Hypothesis-Led Machine Learning and Hierarchical Cluster Analysis to Identify Disease Pathways Prior to Dementia: Longitudinal Cohort Study

Huang, S. T., Hsiao, F. Y., Tsai, T. H., Chen, P. J., Peng, L. N. & Chen, L. K., 2023, 於: Journal of Medical Internet Research. 25, e41858.

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3 引文斯高帕斯（Scopus）

2022

Age and sex differences in associations between self-reported health, physical function, mental function and mortality

Lin, M. H., Chen, L. J., Huang, S. T., Meng, L. C., Lee, W. J., Peng, L. N., Hsiao, F. Y. & Chen, L. K., 1 1月 2022, 於: Archives of Gerontology and Geriatrics. 98, 104537.

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26 引文斯高帕斯（Scopus）

Antiperistaltic effect and safety of l-menthol for esophagogastroduodenoscopy in the elderly with contraindication to hyoscine-N-butylbromide

Yang, T. C., Chen, P. H., Hou, M. C., Peng, L. N., Lin, M. H., Chen, L. K. & Huang, Y. H., 12月 2022, 於: Scientific reports. 12, 1, 10418.

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2 引文斯高帕斯（Scopus）

Biological Features of the Outcome-Based Intrinsic Capacity Composite Scores From a Population-Based Cohort Study: Pas de Deux of Biological and Functional Aging

Meng, L. C., Huang, S. T., Peng, L.-N., Chen, L. K. & Hsiao, F. Y., 4 3月 2022, 於: Frontiers in Medicine. 9, 851882.

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27 引文斯高帕斯（Scopus）

Brain white matter hyperintensities-predicted age reflects neurovascular health in middle-to-old aged subjects

Huang, C. C., Chou, K. H., Lee, W.-J., Yang, C.-C., Tsai, S. J., Chen, L. K., Chung, C. P. & Lin, C. P., 1 5月 2022, 於: Age and Ageing. 51, 5

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5 引文斯高帕斯（Scopus）

Cerebral small vessel disease is associated with concurrent physical and cognitive impairments at preclinical stage

Chung, C. P., Peng, L.-N., Lee, W.-J., Wang, P.-N., Lin, C. P. & Chen, L. K., 1月 2022, 於: Cerebral Circulation - Cognition and Behavior. 3, 100144.

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4 引文斯高帕斯（Scopus）

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