醫學系生物化學科

2024

Dysfunction of Avo3, an essential component of target of rapamycin complex 2, induces ubiquitin-proteasome-dependent downregulation of Avo2 in Saccharomyces cerevisiae

Chen, P. K., Chang, Y. J., Chou, Y. W. & Chen, M. Y., 12 7月 2024, 於: Biochemical and Biophysical Research Communications. 717, 150045.

研究成果: Article › 同行評審

Encapsulation with a complex of acidic/alkaline polysaccharide-whey protein isolate fibril bilayer microcapsules enhances the stability of β-carotene under acidic environments

Yang, Y. Y., Lai, Y. R., How, S. C., Lin, T. H. & Wang, S. S. S., 7月 2024, 於: Journal of the Taiwan Institute of Chemical Engineers. 160, 105344.

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Using silver nanoparticle-decorated whey protein isolate amyloid fibrils to modify the electrode surface used for electrochemical detection of para-nitrophenol

Lai, Y. R., Wang, S. S. S. & Lin, T. H., 4月 2024, 於: International Journal of Biological Macromolecules. 264, 130404.

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5 引文斯高帕斯（Scopus）

Using titanium dioxide nanoparticle-deposited whey protein isolate amyloid fibrils to photocatalyze the degradation of methylene blue

Lai, Y. R., Huang, C. F., How, S. C., Lin, T. H. & Wang, S. S. S., 7月 2024, 於: Journal of the Taiwan Institute of Chemical Engineers. 160, 105313.

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5 引文斯高帕斯（Scopus）

2023

Application of Amyloid-Based Hybrid Membranes in Drug Delivery

Lai, Y. R., Wang, S. S. S., Hsu, T. L., Chou, S. H., How, S. C. & Lin, T. H., 3月 2023, 於: Polymers. 15, 6, 1444.

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11 引文斯高帕斯（Scopus）

Developing targeted drug delivery carriers for breast cancer using glutathione-sensitive doxorubicin-coupled glycated bovine serum albumin nanoparticles

Hsu, W. H., Ku, C. L., Lai, Y. R., Wang, S. S. S., Chou, S. H. & Lin, T. H., 30 9月 2023, 於: International Journal of Biological Macromolecules. 249, 126114.

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4 引文斯高帕斯（Scopus）

2022

Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness

Lin, C. H., Liao, C. C., Wang, S. Y., Peng, C. Y., Yeh, Y. C., Chen, M. Y. & Chou, T. Y., 1 1月 2022, 於: Cancers. 14, 1, 243.

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11 引文斯高帕斯（Scopus）

Erratum: Structural and Biochemical Characterization of Porcine Epidemic Diarrhea Virus Papain-Like Protease 2 (Journal of Virology (2022) 96:1 (e01372-21) DOI: 10.1128/JVI.01372-21)

Chu, H. F., Cheng, S. C., Sun, C. Y., Chou, C. Y., Lin, T.-H. & Chen, W. Y., 3月 2022, 於: Journal of Virology. 96, 6, e00091-22.

研究成果: Comment/debate

Insights to Human γD-Crystallin Unfolding by NMR Spectroscopy and Molecular Dynamics Simulations

Hsueh, S. S., Wang, S. S. S., Chen, S. H., Wang, C. L., Wu, J. W. & Lin, T. H., 1 2月 2022, 於: International Journal Of Molecular Sciences. 23, 3, 1591.

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2 引文斯高帕斯（Scopus）

Silver nanoparticle-deposited whey protein isolate amyloid fibrils as catalysts for the reduction of methylene blue

Lai, Y. R., Lai, J. T., Wang, S. S. S., Kuo, Y. C. & Lin, T. H., 31 7月 2022, 於: International Journal of Biological Macromolecules. 213, p. 1098-1114 17 p.

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18 引文斯高帕斯（Scopus）

Structural and Biochemical Characterization of Porcine Epidemic Diarrhea Virus Papain-Like Protease 2

Chu, H. F., Cheng, S. C., Sun, C. Y., Chou, C. Y., Lin, T.-H. & Chen, W. Y., 1月 2022, 於: Journal of Virology. 96, 1, e01372-21.

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4 引文斯高帕斯（Scopus）

2021

Characterization of Androgen Receptor Complex Associated Protein (ARCAP) in hepatocellular carcinoma and liver

Chang, T. J., Hsia, C. Y., Chau, G. Y., Hsiao, L. T., Huang, K. T., King, K. L., Lui, W. Y., Li, A. F. Y., Wang, C. L., Tsai, P. H., Chien, Y. & Lin, T. H., 1 12月 2021, 於: Journal of the Chinese Medical Association. 84, 12, p. 1100-1108 9 p.

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4 引文斯高帕斯（Scopus）

Disulfiram and 6-Thioguanine synergistically inhibit the enzymatic activities of USP2 and USP21

Lin, H. C., Kuan, Y., Chu, H. F., Cheng, S. C., Pan, H. C., Chen, W. Y., Sun, C. Y. & Lin, T. H., 15 4月 2021, 於: International Journal of Biological Macromolecules. 176, p. 490-497 8 p.

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16 引文斯高帕斯（Scopus）

Examining the effect of bovine serum albumin on the properties and drug release behavior of β-lactoglobulin-derived amyloid fibril-based hydrogels

How, S. C., Lin, T. H., Chang, C. C. & Wang, S. S. S., 1 8月 2021, 於: International Journal of Biological Macromolecules. 184, p. 79-91 13 p.

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22 引文斯高帕斯（Scopus）

Feedback regulation of o-glcnac transferase through translation control to maintain intracellular o-glcnac homeostasis

Lin, C. H., Liao, C. C., Chen, M. Y. & Chou, T. Y., 1 4月 2021, 於: International Journal Of Molecular Sciences. 22, 7, 3463.

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20 引文斯高帕斯（Scopus）

Gene expression profile in primary tumor is associated with brain-tropism of metastasis from lung adenocarcinoma

Lin, Y. Y., Wang, Y. C., Yeh, D. W., Hung, C. Y., Yeh, Y. C., Ho, H. L., Mon, H. C., Chen, M. Y., Wu, Y. C. & Chou, T. Y., 1 12月 2021, 於: International Journal Of Molecular Sciences. 22, 24, 13374.

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8 引文斯高帕斯（Scopus）

Human costars family protein abracl modulates actin dynamics and cell migration and associates with tumorigenic growth

Hsiao, B. Y., Chen, C. H., Chi, H. Y., Yen, P. R., Yu, Y. Z., Lin, C. H., Pang, T. L., Lin, W. C., Li, M. L., Yeh, Y. C., Chou, T. Y. & Chen, M. Y., 2 2月 2021, 於: International Journal Of Molecular Sciences. 22, 4, p. 1-22 22 p., 2037.

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11 引文斯高帕斯（Scopus）

Protection of human γD-crystallin protein from ultraviolet C-induced aggregation by ortho-vanillin

Hsueh, S. S., Lu, J. H., Wu, J. W., Lin, T. H. & Wang, S. S. S., 15 11月 2021, 於: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 261, 120023.

研究成果: Article › 同行評審

6 引文斯高帕斯（Scopus）

USP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer

Huang, Y. T., Cheng, A. C., Tang, H. C., Huang, G. C., Cai, L., Lin, T. H., Wu, K. J., Tseng, P. H., Wang, G. G. & Chen, W. Y., 10月 2021, 於: Cell Death and Disease. 12, 10, 880.

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22 引文斯高帕斯（Scopus）

2020

Cellular prion protein transcriptionally regulated by NFIL3 enhances lung cancer cell lamellipodium formation and migration through JNK signaling

Lin, S. C., Lin, C. H., Shih, N. C., Liu, H. L., Wang, W. C., Lin, K. Y., Liu, Z. Y., Tseng, Y. J., Chang, H. K., Lin, Y. C., Yeh, Y. C., Minato, H., Fujii, T., Wu, Y. C., Chen, M. Y. & Chou, T. Y., 9 1月 2020, 於: Oncogene. 39, 2, p. 385-398 14 p.

研究成果: Article › 同行評審

27 引文斯高帕斯（Scopus）

Conformational characterization of native and L17A/F19A-substituted dutch-typeβ-amyloid peptides

He, K. C., Chen, Y. R., Liang, C. T., Huang, S. J., Tzeng, C. Y., Chang, C. F., Huang, S. J., Huang, H. B. & Lin, T. H., 1 4月 2020, 於: International Journal Of Molecular Sciences. 21, 7, 2571.

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6 引文斯高帕斯（Scopus）

Genomic analysis and comparative multiple sequences of SARS-CoV2

Chang, T. J., Yang, D. M., Wang, M. L., Liang, K. H., Tsai, P. H., Chiou, S. H., Lin, T. H. & Wang, C. T., 6月 2020, 於: Journal of the Chinese Medical Association. 83, 6, p. 537-543 7 p.

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33 引文斯高帕斯（Scopus）

Genomic variance of Open Reading Frames (ORFs) and Spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Tsai, P. H., Wang, M. L., Yang, D. M., Liang, K. H., Chou, S. J., Chiou, S. H., Lin, T. H., Wang, C. T. & Chang, T. J., 8月 2020, 於: Journal of the Chinese Medical Association. 83, 8, p. 725-732 8 p.

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27 引文斯高帕斯（Scopus）

Hunting severe acute respiratory syndrome coronavirus 2 (2019 novel coronavirus): From laboratory testing back to basic research

Yang, D. M., Chang, T. J., Wang, M. L., Tsai, P. H., Lin, T. H., Wang, C. T. & Liang, K. H., 6月 2020, 於: Journal of the Chinese Medical Association. 83, 6, p. 524-526 3 p.

研究成果: Review article › 同行評審

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8 引文斯高帕斯（Scopus）

Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4

Lin, Y. S., Huang, K. Y., Yu, H. C., Lu, M. C., Fan, C. J., Huang Tseng, H. Y., Jhuang, B. Y., Liu, S. Q., Lai, N. S., Lin, T. H. & Huang, H. B., 15 10月 2020, 於: Biochemical and Biophysical Research Communications. 531, 2, p. 236-241 6 p.

研究成果: Article › 同行評審

Novel biosensor platforms for the detection of coronavirus infection and severe acute respiratory syndrome coronavirus 2

Liang, K. H., Chang, T. J., Wang, M. L., Tsai, P. H., Lin, T. H., Wang, C. T. & Yang, D. M., 8月 2020, 於: Journal of the Chinese Medical Association. 83, 8, p. 701-703 3 p.

研究成果: Review article › 同行評審

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26 引文斯高帕斯（Scopus）

2018

Characterization of the interactions between inhibitor-1 and recombinant PP1 by NMR spectroscopy

Liang, C. T., Lin, Y. S., Huang, Y. C., Huang, H. L., Yang, J. Q., Wu, T. H., Chang, C. F., Huang, S. J., Huang, H. B. & Lin, T. H., 1 12月 2018, 於: Scientific reports. 8, 1, 50.

研究成果: Article › 同行評審

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2 引文斯高帕斯（Scopus）

Exploring the effects of methylene blue on amyloid fibrillogenesis of lysozyme

How, S. C., Cheng, Y. H., Lo, C. H., Lai, J. T., Lin, T. H., Bednarikova, Z., Antosova, A., Gazova, Z., Wu, J. W. & Wang, S. S. S., 11月 2018, 於: International Journal of Biological Macromolecules. 119, p. 1059-1067 9 p.

研究成果: Article › 同行評審

25 引文斯高帕斯（Scopus）

High O-linked N-acetylglucosamine transferase expression predicts poor survival in patients with early stage lung adenocarcinoma

Lin, Y. C., Lin, C. H., Yeh, Y. C., Ho, H. L., Wu, Y. C., Chen, M. Y. & Chou, T. Y., 24 7月 2018, 於: Oncotarget. 9, 57, p. 31032-31044 13 p.

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18 引文斯高帕斯（Scopus）

2017

Investigating the effects of erythrosine B on amyloid fibril formation derived from lysozyme

Kuo, C. T., Chen, Y. L., Hsu, W. T., How, S. C., Cheng, Y. H., Hsueh, S. S., Liu, H. S., Lin, T. H., Wu, J. W. & Wang, S. S. S., 1 5月 2017, 於: International Journal of Biological Macromolecules. 98, p. 159-168 10 p.

研究成果: Article › 同行評審

23 引文斯高帕斯（Scopus）

LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration

Lin, Y. H., Zhen, Y. Y., Chien, K. Y., Lee, I. C., Lin, W. C., Chen, M. Y. & Pai, L. M., 15 4月 2017, 於: Molecular Biology of the Cell. 28, 8, p. 1054-1065 12 p.

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48 引文斯高帕斯（Scopus）

2016

L17A/F19A substitutions augment the α-helicity of β-amyloid peptide discordant segment

Liang, C. T., Huang, H. B., Wang, C. C., Chen, Y. R., Chang, C. F., Shiao, M. S., Chen, Y. G. & Lin, T. H., 4月 2016, 於: PLoS ONE. 11, 4, e0154327.

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9 引文斯高帕斯（Scopus）

2015

Actin-binding protein G (AbpG) participates in modulating the actin cytoskeleton and cell migration in Dictyostelium discoideum

Lin, W. C., Wang, L. C., Pang, T. L. & Chen, M. Y., 15 3月 2015, 於: Molecular Biology of the Cell. 26, 6, p. 1084-1097 14 p.

研究成果: Article › 同行評審

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3 引文斯高帕斯（Scopus）

Investigating the effects of plasma pretreatment on the formation of ordered aggregates of lysozyme

Chang, C. K., Chen, W. A., Sie, C. Y., Lin, S. C., Lin, L. T. W., Lin, T. H., Hsu, C. C. & Wang, S. S. S., 1 2月 2015, 於: Colloids and Surfaces B: Biointerfaces. 126, 1, p. 154-161 8 p.

研究成果: Article › 同行評審

6 引文斯高帕斯（Scopus）

MLH1 V384D polymorphism associates with poor response to EGFR tyrosine kinase inhibitors in patients with EGFR L858R-positive lung adenocarcinoma

Chiu, C. H., Ho, H. L., Doong, H., Yeh, Y. C., Chen, M. Y., Chou, T. Y. & Tsai, C. M., 2015, 於: Oncotarget. 6, 10, p. 8407-8417 11 p.

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17 引文斯高帕斯（Scopus）

Resonance assignments and secondary structure of a phytocystatin from Sesamum indicum

Hu, Y. J., Irene, D., Lo, C. J., Cai, Y. L., Tzen, T. C., Lin, T. H. & Chyan, C. L., 22 10月 2015, 於: Biomolecular NMR Assignments. 9, 2, p. 309-311 3 p.

研究成果: Article › 同行評審

9 引文斯高帕斯（Scopus）

Resonance assignments and secondary structure of apolipoprotein E C-terminal domain in DHPC micelles

Lo, C. J., Chyan, C. L., Chen, Y. C., Chang, C. F., Huang, H. B. & Lin, T. H., 4月 2015, 於: Biomolecular NMR Assignments. 9, 1, p. 187-190 4 p.

研究成果: Article › 同行評審

The Arctic mutation accelerates Aβ aggregation in SDS through reducing the helical propensity of residues 15-25

Lo, C. J., Wang, C. C., Huang, H. B., Chang, C. F., Shiao, M. S., Chen, Y. C. & Lin, T. H., 1 3月 2015, 於: Amyloid. 22, 1, p. 8-18 11 p.

研究成果: Article › 同行評審

8 引文斯高帕斯（Scopus）

2014

Association of p21 with NF-YA suppresses the expression of Polo-like kinase 1 and prevents mitotic death in response to DNA damage

Lin, Y. C., Chen, Y. N., Lin, K. F., Wang, F. F., Chou, T. Y. & Chen, M. Y., 1月 2014, 於: Cell Death and Disease. 5, 1, e987.

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12 引文斯高帕斯（Scopus）

Effect of C-terminal residues of Aβ on copper binding affinity, structural conversion and aggregation

Huang, S. H., Ke, S. C., Lin, T. H., Huang, H. B. & Chen, Y. C., 3 3月 2014, 於: PLoS ONE. 9, 3, e90385.

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10 引文斯高帕斯（Scopus）

Identification of the high molecular weight isoform of phostensin

Lin, Y. S., Huang, H. L., Liu, W. T., Lin, T. H. & Huang, H. B., 15 1月 2014, 於: International Journal Of Molecular Sciences. 15, 1, p. 1068-1079 12 p.

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5 引文斯高帕斯（Scopus）

Rad GTPase inhibits the NFκB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation

Hsiao, B. Y., Chang, T. K., Wu, I. T. & Chen, M. Y., 7月 2014, 於: Cellular Signalling. 26, 7, p. 1437-1444 8 p.

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15 引文斯高帕斯（Scopus）

Resonance assignments and secondary structure of calmodulin in complex with its target sequence in rat olfactory cyclic nucleotide-gated ion channel

Irene, D., Sung, F. H., Huang, J. W., Lin, T. H., Chen, Y. C. & Chyan, C. L., 4月 2014, 於: Biomolecular NMR Assignments. 8, 1, p. 97-102 6 p.

研究成果: Article › 同行評審

2013

A novel anti-CCN1 monoclonal antibody suppresses Rac-dependent cytoskeletal reorganization and migratory activities in breast cancer cells

Jim Leu, S. J., Sung, J. S., Huang, M. L., Chen, M. Y. & Tsai, T. W., 17 5月 2013, 於: Biochemical and Biophysical Research Communications. 434, 4, p. 885-891 7 p.

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12 引文斯高帕斯（Scopus）

Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel

Irene, D., Huang, J. W., Chung, T. Y., Li, F. Y., Tzen, J. T. C., Lin, T. H. & Chyan, C. L., 2013, 於: Journal of Biomolecular Structure and Dynamics. 31, 4, p. 414-425 12 p.

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9 引文斯高帕斯（Scopus）

Effect of Alanine Replacement of L17 and F19 on the Aggregation and Neurotoxicity of Arctic-Type Aβ₄₀

Chen, Y. R., Huang, H. B., Lo, C. J., Wang, C. C., Ho, L. K., Liu, H. T., Shiao, M. S., Lin, T. H. & Chen, Y. C., 25 4月 2013, 於: PLoS ONE. 8, 4, e61874.

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8 引文斯高帕斯（Scopus）

Examining the inhibitory actions of copolypeptides against amyloid fibrillogenesis of bovine insulin

Kao, C. Y., Lai, J. K., Lin, T. H., Lin, Y. J., Jan, J. S. & Wang, S. S. S., 5 9月 2013, 於: Biochemical Engineering Journal. 78, p. 181-188 8 p.

研究成果: Article › 同行評審

1 引文斯高帕斯（Scopus）

Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains

Wang, J. Q., Chen, J. H., Chen, Y. C., Chen, M. Y., Hsieh, C. Y., Teng, S. C. & Wu, K. J., 6 6月 2013, 於: PLoS ONE. 8, 6, e65586.

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9 引文斯高帕斯（Scopus）

The matricellular protein CCN1 suppresses lung cancer cell growth by inducing senescence via the p53/p21 pathway

Jim Leu, S. J., Sung, J. S., Chen, M. Y., Chen, C. W., Cheng, J. Y., Wang, T. Y. & Wang, J. J., 9月 2013, 於: Journal of Cellular Biochemistry. 114, 9, p. 2082-2093 12 p.

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15 引文斯高帕斯（Scopus）

2012

Characterization of Aβ aggregation mechanism probed by congo red

Wang, C. C., Huang, H. B., Tsay, H. J., Shiao, M. S., Wu, W. J. W., Cheng, Y. C. & Lin, T. H., 2012, 於: Journal of Biomolecular Structure and Dynamics. 30, 2, p. 160-169 10 p.

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14 引文斯高帕斯（Scopus）

醫學系生物化學科

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