Yolk sac tumor of endometrium: A case report and literature review

Shih-Wen Lin; Shu-Wei Hsieh; Shih-Hung Huang; Hung-Shuo Liang; Chia-Yen Huang

doi:10.1016/j.tjog.2019.09.020

Yolk sac tumor of endometrium: A case report and literature review

Shih-Wen Lin, Shu-Wei Hsieh, Shih-Hung Huang, Hung-Shuo Liang, Chia-Yen Huang

Department of Photonics

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Objective: To report a rare case of endometrial yolk sac tumor (YST) and review published cases of YST of the endometrium.

Case report: A 68-year-old female presented with intermittent vaginal spotting for nine months. An endometrial biopsy showed adenocarcinoma. Complete surgical staging operation was performed and the final pathology revealed stage II endometrial yolk sac tumor. The post-operative a-fetoprotein (AFP) level was 133.4 ng/mL. Post-operative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP) regimen was prescribed for 6 cycles. AFP levels were normal before the fourth cycle of chemotherapy. She is disease free 6 months after completion of therapy.

Conclusion: Primary YSTs arising in the endometrium is an extremely rare disease especially in postmenopausal women. Complete surgical staging operation with adjuvant chemotherapy will lead to good outcome in this disease. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.

Original language	American English
Pages (from-to)	846-848
Number of pages	3
Journal	Taiwanese Journal of Obstetrics and Gynecology
Volume	58
Issue number	6
DOIs	https://doi.org/10.1016/j.tjog.2019.09.020
State	Published - Nov 2019

Keywords

Yolk sac tumor
Endometrial cancer
Adjuvant chemotherapy
ENDODERMAL SINUS TUMOR
DIFFERENTIATION
CARCINOMA

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tjog.2019.09.020

Cite this

@article{f3d068865dcb4ade8ab1991e83f440a4,

title = "Yolk sac tumor of endometrium: A case report and literature review",

abstract = "Objective: To report a rare case of endometrial yolk sac tumor (YST) and review published cases of YST of the endometrium.Case report: A 68-year-old female presented with intermittent vaginal spotting for nine months. An endometrial biopsy showed adenocarcinoma. Complete surgical staging operation was performed and the final pathology revealed stage II endometrial yolk sac tumor. The post-operative a-fetoprotein (AFP) level was 133.4 ng/mL. Post-operative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP) regimen was prescribed for 6 cycles. AFP levels were normal before the fourth cycle of chemotherapy. She is disease free 6 months after completion of therapy.Conclusion: Primary YSTs arising in the endometrium is an extremely rare disease especially in postmenopausal women. Complete surgical staging operation with adjuvant chemotherapy will lead to good outcome in this disease. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.",

keywords = "Yolk sac tumor, Endometrial cancer, Adjuvant chemotherapy, ENDODERMAL SINUS TUMOR, DIFFERENTIATION, CARCINOMA",

author = "Shih-Wen Lin and Shu-Wei Hsieh and Shih-Hung Huang and Hung-Shuo Liang and Chia-Yen Huang",

year = "2019",

month = nov,

doi = "10.1016/j.tjog.2019.09.020",

language = "American English",

volume = "58",

pages = "846--848",

journal = "Taiwanese Journal of Obstetrics and Gynecology",

issn = "1028-4559",

publisher = "Elsevier Taiwan LLC",

number = "6",

}

TY - JOUR

T1 - Yolk sac tumor of endometrium

T2 - A case report and literature review

AU - Lin, Shih-Wen

AU - Hsieh, Shu-Wei

AU - Huang, Shih-Hung

AU - Liang, Hung-Shuo

AU - Huang, Chia-Yen

PY - 2019/11

Y1 - 2019/11

N2 - Objective: To report a rare case of endometrial yolk sac tumor (YST) and review published cases of YST of the endometrium.Case report: A 68-year-old female presented with intermittent vaginal spotting for nine months. An endometrial biopsy showed adenocarcinoma. Complete surgical staging operation was performed and the final pathology revealed stage II endometrial yolk sac tumor. The post-operative a-fetoprotein (AFP) level was 133.4 ng/mL. Post-operative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP) regimen was prescribed for 6 cycles. AFP levels were normal before the fourth cycle of chemotherapy. She is disease free 6 months after completion of therapy.Conclusion: Primary YSTs arising in the endometrium is an extremely rare disease especially in postmenopausal women. Complete surgical staging operation with adjuvant chemotherapy will lead to good outcome in this disease. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.

AB - Objective: To report a rare case of endometrial yolk sac tumor (YST) and review published cases of YST of the endometrium.Case report: A 68-year-old female presented with intermittent vaginal spotting for nine months. An endometrial biopsy showed adenocarcinoma. Complete surgical staging operation was performed and the final pathology revealed stage II endometrial yolk sac tumor. The post-operative a-fetoprotein (AFP) level was 133.4 ng/mL. Post-operative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP) regimen was prescribed for 6 cycles. AFP levels were normal before the fourth cycle of chemotherapy. She is disease free 6 months after completion of therapy.Conclusion: Primary YSTs arising in the endometrium is an extremely rare disease especially in postmenopausal women. Complete surgical staging operation with adjuvant chemotherapy will lead to good outcome in this disease. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.

KW - Yolk sac tumor

KW - Endometrial cancer

KW - Adjuvant chemotherapy

KW - ENDODERMAL SINUS TUMOR

KW - DIFFERENTIATION

KW - CARCINOMA

U2 - 10.1016/j.tjog.2019.09.020

DO - 10.1016/j.tjog.2019.09.020

M3 - Review article

SN - 1028-4559

VL - 58

SP - 846

EP - 848

JO - Taiwanese Journal of Obstetrics and Gynecology

JF - Taiwanese Journal of Obstetrics and Gynecology

IS - 6

ER -

Yolk sac tumor of endometrium: A case report and literature review

Abstract

Keywords

UN SDGs

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