Xanthogranulomatous pyelonephritis treated by partial nephrectomy

Jei Wen Chang, Shu Jen Chen, Tai Wai Chin, Hsin Lin Tsai, Chin Chen Pan, Yum Kung Chu, Chui Mei Tiu, Ling Yu Yang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Xanthogranulomatous pyelonephritis is an uncommon disease in children. We report of a 2-month-old girl with urinary tract infection and with a renal mass detected by ultrasound scan. The preoperative differential diagnoses were Wilms tumor, multicystic dysplastic kidney, renal abscess, and mesoplastic nephroma. The subsequent histopathological findings allowed the diagnosis of xanthogranulomatous pyelonephritis (XGP). Although XGP is rare at this age, it must be considered in the differential diagnosis of a child presenting with renal mass, either with or without associated urolithiasis, anemia, and elevated inflammatory markers. The long-standing mainstay of therapy for diffuse XGP has been nephrectomy. However, we report the successful preservation of renal mass with partial nephrectomy for diffuse XGP. The affected kidney grew normally and preserved residual function after the operation. Hence we strongly suggest parenchymal saving in pediatric cases of XGP to preserve renal function.

Original languageEnglish
Pages (from-to)1164-1167
Number of pages4
JournalPediatric Nephrology
Issue number10
StatePublished - Oct 2004


  • Nephrectomy
  • Xanthogranulomatous pyelonephritis


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