TY - GEN
T1 - Virtual performance evaluation platform for ARGUS microPET
T2 - 8th International Conference on BioMedical Engineering and Informatics, BMEI 2015
AU - Shen, Li Chen Michael
AU - Wu, Cheng Han
AU - Chen, Jyh Cheng
N1 - Publisher Copyright:
© 2015 IEEE.
PY - 2016/2/8
Y1 - 2016/2/8
N2 - Purpose: The primary objective of this study was to assess the performance of a preclinical micro PET/CT (ARGUS-SEDECAL) via GATE, Geant4 Application for Tomographic Emission, a virtual platform for tomographic emission simulation. Methods: By using GATE, we were able to accurately reproduce the physics of a PET scanner, including such as the instrument's parameters, and the data collecting system of an Argus system. A dual-ring detector with the same parameters as compared to the ARGUS was set up via GATE. A dual-layer scanner with 18 modules, with lutetium - yttrium orthosilicate (LYSO) front layer and gadolinium orthosilicate (GSO) rear layer crystal, geometry of the simulated scanner all represented that of the ARGUS model. Results: The data collected from GATE was used to evaluate the uniformity of our images, by calculating the percentage standard deviation (%STD). The %STD of images from Argus showed comparable results to our own self designed modules. Conclusions: This study has shown that GATE can serve well as a relatively unbiased and practical method to evaluate performances of PET scanners without the need of having true instrumentation and physical testing, which in turns can be a very cost-effective method to PET design and performance evaluation.
AB - Purpose: The primary objective of this study was to assess the performance of a preclinical micro PET/CT (ARGUS-SEDECAL) via GATE, Geant4 Application for Tomographic Emission, a virtual platform for tomographic emission simulation. Methods: By using GATE, we were able to accurately reproduce the physics of a PET scanner, including such as the instrument's parameters, and the data collecting system of an Argus system. A dual-ring detector with the same parameters as compared to the ARGUS was set up via GATE. A dual-layer scanner with 18 modules, with lutetium - yttrium orthosilicate (LYSO) front layer and gadolinium orthosilicate (GSO) rear layer crystal, geometry of the simulated scanner all represented that of the ARGUS model. Results: The data collected from GATE was used to evaluate the uniformity of our images, by calculating the percentage standard deviation (%STD). The %STD of images from Argus showed comparable results to our own self designed modules. Conclusions: This study has shown that GATE can serve well as a relatively unbiased and practical method to evaluate performances of PET scanners without the need of having true instrumentation and physical testing, which in turns can be a very cost-effective method to PET design and performance evaluation.
KW - Geant4 Application for Tomographic Emission (GATE)
KW - performance evaluation
KW - Small animal positron emission tomography
KW - virtual simulation
UR - http://www.scopus.com/inward/record.url?scp=84964323946&partnerID=8YFLogxK
U2 - 10.1109/BMEI.2015.7401522
DO - 10.1109/BMEI.2015.7401522
M3 - Conference contribution
AN - SCOPUS:84964323946
T3 - Proceedings - 2015 8th International Conference on BioMedical Engineering and Informatics, BMEI 2015
SP - 318
EP - 322
BT - Proceedings - 2015 8th International Conference on BioMedical Engineering and Informatics, BMEI 2015
A2 - Tao, Zhiyong
A2 - Bai, Li
A2 - Lin, Sen
A2 - Sun, Jinguang
A2 - Wang, Lipo
A2 - Shao, Liangshan
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 14 October 2015 through 16 October 2015
ER -