Venous gangrene in a patient with adenocarcinoma of the lung

Muh Hwa Yang, Frank S. Fan*, Po Min Chen, Jin Hwang Liu, Tzeon Jye Chiou, Wei Shu Wang, Chueh Chuan Yen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Cancer-related thromboembolism is a severe but not uncommon paraneoplastic syndrome in mucinous cancer patients. However, cancer-induced venous gangrene is extremely rare and has never been reported in the English literature. Here, we present a case of lung cancer complicated with venous gangrene of the left foot. An elevated serum anticardiolipin level was detected during hospitalization, but the patient's clinical condition stabilized after heparinization. We suggest that in cancer patients, an elevated serum anticardiolipin antibody level might be a warning sign of an impending thrombotic event and that low-molecular-weight heparin is a sensible choice in treating this kind of cancer-related thromboembolism.

Original languageEnglish
Pages (from-to)276-278
Number of pages3
JournalJapanese journal of clinical oncology
Issue number6
StatePublished - 2000


  • Anticardiolipin antibodies
  • Lung cancer
  • Venous gangrene


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