Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation

Chen Chia Chen; Shan Yu Lin; Jeng-Tzong Sheu

doi:10.1109/NEMS.2011.6017478

Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation

Chen Chia Chen, Shan Yu Lin, Jeng-Tzong Sheu^*

^*Corresponding author for this work

Institute of Nonotechnology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

4 Scopus citations

Abstract

Some properties of living cells are associated with cell adhesion and cell spreading process. Traditional way to monitor cells' morphological changes is usually the use of optical microscope. Biosensors provide an alternative to automatically monitor cell adhesion and spreading process. This study utilized microelectrodes array based impedance biosensors to record cells attachment and differentiation via changes of impedance. The results were confirmed with the images of optical microscope. Based on the electrical model proposed, cell adhesion and differentiation can be clearly identified without any additional biochemical tests.

Original language	English
Title of host publication	NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
Pages	813-816
Number of pages	4
DOIs	https://doi.org/10.1109/NEMS.2011.6017478
State	Published - 20 Feb 2011
Event	6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan Duration: 20 Feb 2011 → 23 Feb 2011

Publication series

Name	NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Conference

Conference	6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
Country/Territory	Taiwan
City	Kaohsiung
Period	20/02/11 → 23/02/11

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10.1109/NEMS.2011.6017478

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Chen, C. C., Lin, S. Y., & Sheu, J.-T. (2011). Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation. In NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (pp. 813-816). Article 6017478 (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems). https://doi.org/10.1109/NEMS.2011.6017478

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title = "Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation",

abstract = "Some properties of living cells are associated with cell adhesion and cell spreading process. Traditional way to monitor cells' morphological changes is usually the use of optical microscope. Biosensors provide an alternative to automatically monitor cell adhesion and spreading process. This study utilized microelectrodes array based impedance biosensors to record cells attachment and differentiation via changes of impedance. The results were confirmed with the images of optical microscope. Based on the electrical model proposed, cell adhesion and differentiation can be clearly identified without any additional biochemical tests.",

author = "Chen, {Chen Chia} and Lin, {Shan Yu} and Jeng-Tzong Sheu",

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Chen, CC, Lin, SY & Sheu, J-T 2011, Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation. in NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems., 6017478, NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, pp. 813-816, 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011, Kaohsiung, Taiwan, 20/02/11. https://doi.org/10.1109/NEMS.2011.6017478

Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation. / Chen, Chen Chia; Lin, Shan Yu; Sheu, Jeng-Tzong.
NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems. 2011. p. 813-816 6017478 (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - Some properties of living cells are associated with cell adhesion and cell spreading process. Traditional way to monitor cells' morphological changes is usually the use of optical microscope. Biosensors provide an alternative to automatically monitor cell adhesion and spreading process. This study utilized microelectrodes array based impedance biosensors to record cells attachment and differentiation via changes of impedance. The results were confirmed with the images of optical microscope. Based on the electrical model proposed, cell adhesion and differentiation can be clearly identified without any additional biochemical tests.

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Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation

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