@inproceedings{1accfb38bcf9424ca1a1b493790a00ea,
title = "Using Deep Learning to Identify Cell and Particle in Live-Cell Time-lapse Images",
abstract = "Live-cell time-lapse images generated by biological experiments are useful for observing activities, even for proposing novel hypotheses. In past work, we had proposed a particle-cell relation mining method, abbreviate to PCRM, which involved identifying particles and cells as objects from live-cell time-lapse images at first. Then PCRM is used to track the pathways of particles to calculate the measures as distances between the particles and cells. Finally, the relationship of particles and cells can be quantified by PCRM. The PCRM is useful for biologists to prove their hypotheses. However,it is very time-consuming when identifying the objects among a large number of biological images. Hence, in this paper, we propose a method using deep learning technology, abbreviated to PCOD, to accelerate the particle and cell identification. The PCOD method achieves the accuracies of 90.2% and 99.9% for particles and cells identification, respectively. In this way, the overall particles and cells can be identified in real time.",
keywords = "CNN, Deep Learning, live-cell time-lapse image, particle and cell identification, real-time object identification",
author = "Cheng, {Hui Jun} and Lin, {Chun Yuan} and Wu, {Cheng Xian} and Hung, {Che Lun} and Chen, {Wei Hsiang} and Tang, {Chuan Yi}",
note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; null ; Conference date: 03-12-2018 Through 06-12-2018",
year = "2019",
month = jan,
day = "21",
doi = "10.1109/BIBM.2018.8621567",
language = "English",
series = "Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "1327--1331",
editor = "Harald Schmidt and David Griol and Haiying Wang and Jan Baumbach and Huiru Zheng and Zoraida Callejas and Xiaohua Hu and Julie Dickerson and Le Zhang",
booktitle = "Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018",
address = "United States",
}