Tuning the Emission of Semiconducting Polymer Dots from Green to Near-Infrared by Alternating Donor Monomers and Their Applications for in Vivo Biological Imaging

Sz Yu Liou; Chi Shiang Ke; Jhih Han Chen; Yun Wen Luo; Shih Yu Kuo; You Hong Chen; Chia Chia Fang; Chang Yi Wu; Chao Ming Chiang; Yang-Hsiang Chan

doi:10.1021/acsmacrolett.5b00842

Tuning the Emission of Semiconducting Polymer Dots from Green to Near-Infrared by Alternating Donor Monomers and Their Applications for in Vivo Biological Imaging

Sz Yu Liou, Chi Shiang Ke, Jhih Han Chen, Yun Wen Luo, Shih Yu Kuo, You Hong Chen, Chia Chia Fang, Chang Yi Wu, Chao Ming Chiang, Yang-Hsiang Chan^*

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Semiconducting polymer dots (Pdots) recently have emerged as a new class of extraordinarily bright fluorescent probes with promising applications in biological imaging and sensing. Herein multicolor semiconducting polymer nanoparticles (Pdots) were designed using benzothiadiazole (BT) as the acceptor, and various types of donors were incorporated to modulate their emission wavelengths. Specific cellular targeting and in vivo biotoxicity as well as microangiography imaging on zebrafish indicated these BT-based Pdots are promising candidates for biological applications.

Original language	English
Pages (from-to)	154-157
Number of pages	4
Journal	ACS Macro Letters
Volume	5
Issue number	1
DOIs	https://doi.org/10.1021/acsmacrolett.5b00842
State	Published - 19 Jan 2016

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Liou, S. Y., Ke, C. S., Chen, J. H., Luo, Y. W., Kuo, S. Y., Chen, Y. H., Fang, C. C., Wu, C. Y., Chiang, C. M., & Chan, Y.-H. (2016). Tuning the Emission of Semiconducting Polymer Dots from Green to Near-Infrared by Alternating Donor Monomers and Their Applications for in Vivo Biological Imaging. ACS Macro Letters, 5(1), 154-157. https://doi.org/10.1021/acsmacrolett.5b00842

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abstract = "Semiconducting polymer dots (Pdots) recently have emerged as a new class of extraordinarily bright fluorescent probes with promising applications in biological imaging and sensing. Herein multicolor semiconducting polymer nanoparticles (Pdots) were designed using benzothiadiazole (BT) as the acceptor, and various types of donors were incorporated to modulate their emission wavelengths. Specific cellular targeting and in vivo biotoxicity as well as microangiography imaging on zebrafish indicated these BT-based Pdots are promising candidates for biological applications.",

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doi = "10.1021/acsmacrolett.5b00842",

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AU - Liou, Sz Yu

AU - Ke, Chi Shiang

AU - Chen, Jhih Han

AU - Luo, Yun Wen

AU - Kuo, Shih Yu

AU - Chen, You Hong

AU - Fang, Chia Chia

AU - Wu, Chang Yi

AU - Chiang, Chao Ming

AU - Chan, Yang-Hsiang

PY - 2016/1/19

Y1 - 2016/1/19

N2 - Semiconducting polymer dots (Pdots) recently have emerged as a new class of extraordinarily bright fluorescent probes with promising applications in biological imaging and sensing. Herein multicolor semiconducting polymer nanoparticles (Pdots) were designed using benzothiadiazole (BT) as the acceptor, and various types of donors were incorporated to modulate their emission wavelengths. Specific cellular targeting and in vivo biotoxicity as well as microangiography imaging on zebrafish indicated these BT-based Pdots are promising candidates for biological applications.

AB - Semiconducting polymer dots (Pdots) recently have emerged as a new class of extraordinarily bright fluorescent probes with promising applications in biological imaging and sensing. Herein multicolor semiconducting polymer nanoparticles (Pdots) were designed using benzothiadiazole (BT) as the acceptor, and various types of donors were incorporated to modulate their emission wavelengths. Specific cellular targeting and in vivo biotoxicity as well as microangiography imaging on zebrafish indicated these BT-based Pdots are promising candidates for biological applications.

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IS - 1

ER -

Tuning the Emission of Semiconducting Polymer Dots from Green to Near-Infrared by Alternating Donor Monomers and Their Applications for in Vivo Biological Imaging

Abstract

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