Tubulointerstitial nephritis and uveitis syndrome (TINU) with Fanconi's syndrome

Y. H. Yao, C. C. Lin, Y. M. Chung, A. H. Yang, S. Y. Li, C. C. Lin, Y. P. Lin, W. C. Yang, C. Y. Yang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


We report a 57-year-old woman with concurrent tubulointerstitial nephritis and uveitis syndrome (TINU) and Fanconi's syndrome. She presented with sudden onset of bilateral ocular pain, blurred vision, acute renal failure, glucosuria and proteinuria. Slit lamp examination revealed acute bilateral anterior uveitis. Tubulointerstitial nephritis was confirmed by kidney biopsy. Laboratory examination revealed normoglycemic glucosuria, proteinuria, normal anion-gapmetabolic acidosis, phosphaturia, urinary uric acid wasting and kaliuresis leading to hypokalemia. Her vision and renal function improved gradually after systemic steroid therapy. There have been rare reports of TINU syndrome which had features of Fanconi's syndrome. The prevalence of TINU syndrome may be underestimated, and its association with Fanconi's syndrome requires further investigation.

Original languageEnglish
Pages (from-to)S75-S78
JournalClinical Nephrology
Issue numberSUPPL. 1
StatePublished - 2011


  • Fanconi's syndrome
  • TINU syndrome
  • Tubulointerstitial nephritis
  • Uveitis


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