Thickness dependence of optical second harmonic generation in collagen fibrils

Shi Wei Chu; Shih Peng Tai; Ming Che Chan; Chi Kuang Sun; I. Ching Hsiao; Chi Hung Lin; Yung Chih Chen; Bai G. Lin

doi:10.1364/OE.15.012005

Thickness dependence of optical second harmonic generation in collagen fibrils

Shi Wei Chu^*, Shih Peng Tai, Ming Che Chan, Chi Kuang Sun, I. Ching Hsiao, Chi Hung Lin, Yung Chih Chen, Bai G. Lin

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Simultaneous backward and forward second harmonic generations from isolated type-I collagen matrix are observed. Optical interference behaviors of these nonlinear optical signals are studied with accurately determined fibril thickness by an atomic force microscope. The nonlinear emission directions are strongly dependent on the coherent interaction within and between collagen fibrils. A linear relationship is obtained to estimate collagen fibril thickness with nanometer precision noninvasively by evaluating the forward/backward second harmonic generation ratio.

Original language	English
Pages (from-to)	12005-12010
Number of pages	6
Journal	Optics Express
Volume	15
Issue number	19
DOIs	https://doi.org/10.1364/OE.15.012005
State	Published - 17 Sep 2007

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title = "Thickness dependence of optical second harmonic generation in collagen fibrils",

abstract = "Simultaneous backward and forward second harmonic generations from isolated type-I collagen matrix are observed. Optical interference behaviors of these nonlinear optical signals are studied with accurately determined fibril thickness by an atomic force microscope. The nonlinear emission directions are strongly dependent on the coherent interaction within and between collagen fibrils. A linear relationship is obtained to estimate collagen fibril thickness with nanometer precision noninvasively by evaluating the forward/backward second harmonic generation ratio.",

author = "Chu, {Shi Wei} and Tai, {Shih Peng} and Chan, {Ming Che} and Sun, {Chi Kuang} and Hsiao, {I. Ching} and Lin, {Chi Hung} and Chen, {Yung Chih} and Lin, {Bai G.}",

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T1 - Thickness dependence of optical second harmonic generation in collagen fibrils

AU - Chu, Shi Wei

AU - Tai, Shih Peng

AU - Chan, Ming Che

AU - Sun, Chi Kuang

AU - Hsiao, I. Ching

AU - Lin, Chi Hung

AU - Chen, Yung Chih

AU - Lin, Bai G.

PY - 2007/9/17

Y1 - 2007/9/17

N2 - Simultaneous backward and forward second harmonic generations from isolated type-I collagen matrix are observed. Optical interference behaviors of these nonlinear optical signals are studied with accurately determined fibril thickness by an atomic force microscope. The nonlinear emission directions are strongly dependent on the coherent interaction within and between collagen fibrils. A linear relationship is obtained to estimate collagen fibril thickness with nanometer precision noninvasively by evaluating the forward/backward second harmonic generation ratio.

AB - Simultaneous backward and forward second harmonic generations from isolated type-I collagen matrix are observed. Optical interference behaviors of these nonlinear optical signals are studied with accurately determined fibril thickness by an atomic force microscope. The nonlinear emission directions are strongly dependent on the coherent interaction within and between collagen fibrils. A linear relationship is obtained to estimate collagen fibril thickness with nanometer precision noninvasively by evaluating the forward/backward second harmonic generation ratio.

UR - http://www.scopus.com/inward/record.url?scp=34648828769&partnerID=8YFLogxK

U2 - 10.1364/OE.15.012005

DO - 10.1364/OE.15.012005

M3 - Article

C2 - 19547564

AN - SCOPUS:34648828769

SN - 1094-4087

VL - 15

SP - 12005

EP - 12010

JO - Optics Express

JF - Optics Express

IS - 19

ER -

Thickness dependence of optical second harmonic generation in collagen fibrils

Abstract

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