The Prevalence and Clinical Phenotypes of Cluster Headache in Relation with Latitude

Yi Chia Liaw, Shih Pin Chen, Shuu Jiun Wang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Purpose of Review: Previous studies have indicated a possible link between the prevalence of cluster headache (CH) and sunlight exposure. However, this theory has yet to be tested systemically. In this article, we aim to examine how latitude affects the prevalence and phenotypes of CH. Recent Findings: To our knowledge, there is by far no article describing the effect of latitude on disease phenotype; thus, we performed a literature review. We noted positive effects of latitude on 1-year prevalence, the proportion of chronic CH, and the proportion of miosis and/or ptosis. Summary: Latitude may affect the phenotypic presentations of cluster headache, probably partially mediated via temperature and sunlight variations. Still, other factors, such as environmental exposure to smoking and the genetic difference between the Eastern and Western populations, may participate in the pathogenesis and clinical manifestations of CH.

Original languageEnglish
Pages (from-to)427-438
Number of pages12
JournalCurrent Pain and Headache Reports
Volume28
Issue number5
DOIs
StatePublished - May 2024

Keywords

  • 1-year prevalence
  • Cluster headache
  • Cranial autonomic symptoms
  • Latitude
  • Lifetime prevalence

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