The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

Yoshiki Kohmura; Shun Min Yang; Hsiang Hsin Chen; Hidekazu Takano; Chia Ju Chang; Ya Sian Wang; Tsung Tse Lee; Ching Yu Chiu; Kai En Yang; Yu Ting Chien; Huan Ming Hu; Tzu Ling Su; Cyril Petibois; Yi Yun Chen; Cheng Huan Hsu; Peilin Chen; Dueng Yuan Hueng; Shean Jen Chen; Chi Lin Yang; An Lun Chin; Chian Ming Low; Francis Chee Kuan Tan; Alvin Teo; Eng Soon Tok; Xu Xiang Cai; Hong Ming Lin; John Boeckl; Anton P. Stampfl; Jumpei Yamada; Satoshi Matsuyama; Tetsuya Ishikawa; Giorgio Margaritondo; Ann Shyn Chiang; Yeukuang Hwu

doi:10.1038/s41598-022-13377-w

The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

Yoshiki Kohmura^*
, Shun Min Yang
, Hsiang Hsin Chen
, Hidekazu Takano
, Chia Ju Chang
, Ya Sian Wang
, Tsung Tse Lee
, Ching Yu Chiu
, Kai En Yang
, Yu Ting Chien
, Huan Ming Hu
, Tzu Ling Su
, Cyril Petibois
, Yi Yun Chen
, Cheng Huan Hsu
, Peilin Chen
, Dueng Yuan Hueng
, Shean Jen Chen
, Chi Lin Yang
, An Lun Chin

Chian Ming Low, Francis Chee Kuan Tan, Alvin Teo, Eng Soon Tok, Xu Xiang Cai, Hong Ming Lin, John Boeckl, Anton P. Stampfl, Jumpei Yamada, Satoshi Matsuyama, Tetsuya Ishikawa, Giorgio Margaritondo, Ann Shyn Chiang, Yeukuang Hwu^*

^*Corresponding author for this work

Institute of Imaging and Biomedical Photonics

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience—an Asia–Pacific Strategic Enterprise (SYNAPSE) collaboration.

Original language	English
Article number	9668
Journal	Scientific reports
Volume	12
Issue number	1
DOIs	https://doi.org/10.1038/s41598-022-13377-w
State	Published - Dec 2022

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Kohmura, Y., Yang, S. M., Chen, H. H., Takano, H., Chang, C. J., Wang, Y. S., Lee, T. T., Chiu, C. Y., Yang, K. E., Chien, Y. T., Hu, H. M., Su, T. L., Petibois, C., Chen, Y. Y., Hsu, C. H., Chen, P., Hueng, D. Y., Chen, S. J., Yang, C. L., ... Hwu, Y. (2022). The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution. Scientific reports, 12(1), Article 9668. https://doi.org/10.1038/s41598-022-13377-w

@article{564e7e348fab4eada4f8b13822f17d0e,

title = "The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution",

abstract = "Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience—an Asia–Pacific Strategic Enterprise (SYNAPSE) collaboration.",

author = "Yoshiki Kohmura and Yang, \{Shun Min\} and Chen, \{Hsiang Hsin\} and Hidekazu Takano and Chang, \{Chia Ju\} and Wang, \{Ya Sian\} and Lee, \{Tsung Tse\} and Chiu, \{Ching Yu\} and Yang, \{Kai En\} and Chien, \{Yu Ting\} and Hu, \{Huan Ming\} and Su, \{Tzu Ling\} and Cyril Petibois and Chen, \{Yi Yun\} and Hsu, \{Cheng Huan\} and Peilin Chen and Hueng, \{Dueng Yuan\} and Chen, \{Shean Jen\} and Yang, \{Chi Lin\} and Chin, \{An Lun\} and Low, \{Chian Ming\} and Tan, \{Francis Chee Kuan\} and Alvin Teo and Tok, \{Eng Soon\} and Cai, \{Xu Xiang\} and Lin, \{Hong Ming\} and John Boeckl and Stampfl, \{Anton P.\} and Jumpei Yamada and Satoshi Matsuyama and Tetsuya Ishikawa and Giorgio Margaritondo and Chiang, \{Ann Shyn\} and Yeukuang Hwu",

note = "Publisher Copyright: {\textcopyright} 2022, The Author(s).",

year = "2022",

month = dec,

doi = "10.1038/s41598-022-13377-w",

language = "English",

volume = "12",

journal = "Scientific reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

number = "1",

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Kohmura, Y, Yang, SM, Chen, HH, Takano, H, Chang, CJ, Wang, YS, Lee, TT, Chiu, CY, Yang, KE, Chien, YT, Hu, HM, Su, TL, Petibois, C, Chen, YY, Hsu, CH, Chen, P, Hueng, DY, Chen, SJ, Yang, CL, Chin, AL, Low, CM, Tan, FCK, Teo, A, Tok, ES, Cai, XX, Lin, HM, Boeckl, J, Stampfl, AP, Yamada, J, Matsuyama, S, Ishikawa, T, Margaritondo, G, Chiang, AS & Hwu, Y 2022, 'The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution', Scientific reports, vol. 12, no. 1, 9668. https://doi.org/10.1038/s41598-022-13377-w

TY - JOUR

T1 - The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

AU - Kohmura, Yoshiki

AU - Yang, Shun Min

AU - Chen, Hsiang Hsin

AU - Takano, Hidekazu

AU - Chang, Chia Ju

AU - Wang, Ya Sian

AU - Lee, Tsung Tse

AU - Chiu, Ching Yu

AU - Yang, Kai En

AU - Chien, Yu Ting

AU - Hu, Huan Ming

AU - Su, Tzu Ling

AU - Petibois, Cyril

AU - Chen, Yi Yun

AU - Hsu, Cheng Huan

AU - Chen, Peilin

AU - Hueng, Dueng Yuan

AU - Chen, Shean Jen

AU - Yang, Chi Lin

AU - Chin, An Lun

AU - Low, Chian Ming

AU - Tan, Francis Chee Kuan

AU - Teo, Alvin

AU - Tok, Eng Soon

AU - Cai, Xu Xiang

AU - Lin, Hong Ming

AU - Boeckl, John

AU - Stampfl, Anton P.

AU - Yamada, Jumpei

AU - Matsuyama, Satoshi

AU - Ishikawa, Tetsuya

AU - Margaritondo, Giorgio

AU - Chiang, Ann Shyn

AU - Hwu, Yeukuang

PY - 2022/12

Y1 - 2022/12

N2 - Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience—an Asia–Pacific Strategic Enterprise (SYNAPSE) collaboration.

AB - Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience—an Asia–Pacific Strategic Enterprise (SYNAPSE) collaboration.

UR - https://www.scopus.com/pages/publications/85131794515

U2 - 10.1038/s41598-022-13377-w

DO - 10.1038/s41598-022-13377-w

M3 - Article

C2 - 35690597

AN - SCOPUS:85131794515

SN - 2045-2322

VL - 12

JO - Scientific reports

JF - Scientific reports

IS - 1

M1 - 9668

ER -

The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

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