The effect of osteoarthritis on 1-year risk of ischemic heart disease following total knee arthroplasty

Chao Feng Lin; Ju Chi Liu; Nai Fang Chi; Yen Shuo Chiu; Han Shui Hsu; Li Nien Chien

doi:10.1016/j.arth.2014.01.032

The effect of osteoarthritis on 1-year risk of ischemic heart disease following total knee arthroplasty

Chao Feng Lin, Ju Chi Liu, Nai Fang Chi, Yen Shuo Chiu, Han Shui Hsu^*, Li Nien Chien

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

To evaluate the long-term risk of ischemic heart disease (IHD) following total knee arthroplasty (TKA), we conducted a retrospective cohort study using data from the National Health Insurance Research Database of Taiwan. We evaluated 3599 primary TKA patients and 14,396 matched control patients. We further classified all patients into those with and without osteoarthritis (OA). The incidence rate of IHD was significantly higher among the TKA patients than among the matched control patients (1.13 vs 0.69 per 1000 person-months, P< .05). However, after controlling for OA, this difference was non-significant (HR = 1.18, 95% confidence interval (CI): 0.63-2.20, P> .05). Our study results indicate that underlying OA conditions are predominantly responsible for increased long-term risk of IHD in TKA patients.

Original language	English
Pages (from-to)	2447-2451.e1
Journal	Journal of Arthroplasty
Volume	29
Issue number	12
DOIs	https://doi.org/10.1016/j.arth.2014.01.032
State	Published - 1 Dec 2014

Keywords

Ischemic heart disease
Osteoarthritis
Propensity score
Total knee arthroplasty

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10.1016/j.arth.2014.01.032

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title = "The effect of osteoarthritis on 1-year risk of ischemic heart disease following total knee arthroplasty",

abstract = "To evaluate the long-term risk of ischemic heart disease (IHD) following total knee arthroplasty (TKA), we conducted a retrospective cohort study using data from the National Health Insurance Research Database of Taiwan. We evaluated 3599 primary TKA patients and 14,396 matched control patients. We further classified all patients into those with and without osteoarthritis (OA). The incidence rate of IHD was significantly higher among the TKA patients than among the matched control patients (1.13 vs 0.69 per 1000 person-months, P< .05). However, after controlling for OA, this difference was non-significant (HR = 1.18, 95% confidence interval (CI): 0.63-2.20, P> .05). Our study results indicate that underlying OA conditions are predominantly responsible for increased long-term risk of IHD in TKA patients.",

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AU - Liu, Ju Chi

AU - Chi, Nai Fang

AU - Chiu, Yen Shuo

AU - Hsu, Han Shui

AU - Chien, Li Nien

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The effect of osteoarthritis on 1-year risk of ischemic heart disease following total knee arthroplasty

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Keywords

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