The effect of far-infrared therapy on the peritoneal membrane transport characteristics of uremic patients undergoing peritoneal dialysis: An open-prospective proof-of-concept study

Ching Po Li, Chyong Mei Chen, Chia Hao Chan, Szu Yuan Li, Ming Tsun Tsai, Chun Fan Chen, Yung Tai Chen, Tz Heng Chen, Fan Yu Chen, Ching Han Yang, Yi Hsin Chou, Tsung Yueh Wang, Ann Charis Tan*, Chih Ching Lin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Long-term peritoneal dialysis (PD) can lead to detrimental changes in peritoneal membrane function, which may be related to the accumulation of glucose degradation products. A pre-vious study demonstrated that 6 months of far-infrared (FIR) therapy may decrease glucose degradation products in PD dialysate. Due to limited literature on this matter, this study aims to investi-gate the effect of FIR therapy on the peritoneal membrane transport characteristics of PD patients. Patients were grouped according to baseline peritoneal transport status: lower transporters (low and low-average) and higher transporters (high-average and high). Both groups underwent 40 min of FIR therapy twice daily for 1 year. In lower transporters, FIR therapy increased weekly dialysate creatinine clearance (6.91 L/wk/1.73 m2; p = 0.04) and D/P creatinine (0.05; p = 0.01). In higher trans-porters, FIR therapy decreased D/P creatinine (−0.05; p = 0.01) and increased D/D0 glucose (0.05; p = 0.006). Fifty percent of high transporter patients shifted to high-average status after FIR therapy. FIR therapy may decrease D/P creatinine for patients in the higher transporter group and cause high transporters to shift to high-average status, which suggests the potential of FIR therapy in improving peritoneal membrane function in PD patients.

Original languageEnglish
Article number669
Number of pages10
JournalMembranes
Volume11
Issue number9
DOIs
StatePublished - Sep 2021

Keywords

  • D/P creatinine ratio
  • End-stage renal disease
  • Far-infrared therapy
  • Peritoneal dialysis
  • Peritoneal membrane transport

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