The core of hepatitis C virus pathogenesis

C. Cheng Kao; Guanghui Yi; Hsuan Cheng Huang

doi:10.1016/j.coviro.2016.01.009

The core of hepatitis C virus pathogenesis

C. Cheng Kao^*
, Guanghui Yi
, Hsuan Cheng Huang

^*Corresponding author for this work

Institute of Biomedical Informatics

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.

Original language	English
Pages (from-to)	66-73
Number of pages	8
Journal	Current Opinion in Virology
Volume	17
DOIs	https://doi.org/10.1016/j.coviro.2016.01.009
State	Published - 1 Apr 2016

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SDG 3 Good Health and Well-being

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10.1016/j.coviro.2016.01.009

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@article{b0ad3600904d4d30b687ca8997292097,

title = "The core of hepatitis C virus pathogenesis",

abstract = "Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.",

author = "Kao, \{C. Cheng\} and Guanghui Yi and Huang, \{Hsuan Cheng\}",

year = "2016",

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doi = "10.1016/j.coviro.2016.01.009",

language = "English",

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journal = "Current Opinion in Virology",

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T1 - The core of hepatitis C virus pathogenesis

AU - Kao, C. Cheng

AU - Yi, Guanghui

AU - Huang, Hsuan Cheng

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.

AB - Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.

UR - https://www.scopus.com/pages/publications/84964647174

U2 - 10.1016/j.coviro.2016.01.009

DO - 10.1016/j.coviro.2016.01.009

M3 - Review article

C2 - 26851516

AN - SCOPUS:84964647174

SN - 1879-6257

VL - 17

SP - 66

EP - 73

JO - Current Opinion in Virology

JF - Current Opinion in Virology

ER -

The core of hepatitis C virus pathogenesis

Abstract

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