TY - JOUR
T1 - The clinical and electroanatomical characteristics of paroxysmal lone atrial fibrillation
AU - Tuan, Ta Chuan
AU - Chang, Shih Lin
AU - Lin, Yenn Jiang
AU - Hu, Yu Feng
AU - Lo, Li Wei
AU - Chao, Tze Fan
AU - Chung, Fa Po
AU - Tai, Ching Tai
AU - Chen, Shih Ann
N1 - Funding Information:
This work was supported by the intramural grant (V100C-177) from Taipei Veterans General Hospital, Taiwan.
PY - 2012/6
Y1 - 2012/6
N2 - Introduction: Lone atrial fibrillation (AF) is defined as AF occurring in the absence of any other cardiovascular disease. The prognosis of patients with lone AF varies in previous studies, and the clinical and electroanatomical characteristics of lone AF are unclear. The purpose of this study was to investigate the clinical characteristics of lone AF. Methods: This study included 203 patients (52713 years old, 144 males) that underwent circumferential pulmonary vein isolation (CPVI) for paroxysmal AF. The mean voltage and total activation time of the individual atria were obtained by using a NavX mapping system and were compared for patients with lone and non-lone AF. Several parameters, including the age, gender, AF duration, and left atrial (LA) diameter were analyzed. Results: Compared with non-lone AF patients, lone AF patients were significantly younger (49713 years old vs. 58711 years old, p<0.001) and had lower body-mass index (BMI, 24.6072.96 vs. 26.0773.29, p=0.02), lesser cholesterol level (169.06731.41 vs. 183.63731.12, p=0.014), smaller LA diameter (35.8974.90 vs. 40.8674.62, p<0.001), and higher LA bipolar voltage (2.1070.50 vs. 1.8370.73 mV, p<0.05). Furthermore, a dramatic voltage reduction was observed for 60-year-old patients. Conclusion: Patients with lone AF have unique clinical and electroanatomical characteristics.
AB - Introduction: Lone atrial fibrillation (AF) is defined as AF occurring in the absence of any other cardiovascular disease. The prognosis of patients with lone AF varies in previous studies, and the clinical and electroanatomical characteristics of lone AF are unclear. The purpose of this study was to investigate the clinical characteristics of lone AF. Methods: This study included 203 patients (52713 years old, 144 males) that underwent circumferential pulmonary vein isolation (CPVI) for paroxysmal AF. The mean voltage and total activation time of the individual atria were obtained by using a NavX mapping system and were compared for patients with lone and non-lone AF. Several parameters, including the age, gender, AF duration, and left atrial (LA) diameter were analyzed. Results: Compared with non-lone AF patients, lone AF patients were significantly younger (49713 years old vs. 58711 years old, p<0.001) and had lower body-mass index (BMI, 24.6072.96 vs. 26.0773.29, p=0.02), lesser cholesterol level (169.06731.41 vs. 183.63731.12, p=0.014), smaller LA diameter (35.8974.90 vs. 40.8674.62, p<0.001), and higher LA bipolar voltage (2.1070.50 vs. 1.8370.73 mV, p<0.05). Furthermore, a dramatic voltage reduction was observed for 60-year-old patients. Conclusion: Patients with lone AF have unique clinical and electroanatomical characteristics.
KW - Lone atrial fibrillation
KW - Pulmonary vein isolation
KW - Voltage
UR - http://www.scopus.com/inward/record.url?scp=84870394648&partnerID=8YFLogxK
U2 - 10.1016/j.joa.2012.01.001
DO - 10.1016/j.joa.2012.01.001
M3 - Article
AN - SCOPUS:84870394648
SN - 1880-4276
VL - 28
SP - 182
EP - 186
JO - journal of arrhythmia
JF - journal of arrhythmia
IS - 3
ER -
