Surgical management of primary retroperitoneal sarcoma

Tai Yuan Wang*, Su Shun Lo, Cheng Hsi Su, Chew Wun Wu, Wing Yiu Lui

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background. Retroperitoneal sarcoma is a rare and challenging group of diseases for surgeons, characterized by extensive growth and high recurrent rate. We analyzed data from our patients to identify the factors of survival. Methods. From 1971 to 1993, medical records of 40 patients with primary retroperitoneal sarcoma were reviewed. Clinical factors including age, sex, tumor size, histopathology, type of operation, disease-free interval, and number of operation were collected to correlate with patient's survival. Results. Most patients presented with huge abdominal mass. There were 22 liposarcomas, 8 leiomyosarcomas, 5 malignant fibrous histiocytomas, 2 fibrosarcomas, 2 malignant mesenchymomas and one rhabdomyosarcoma. Twenty-eight patients received complete resection and 12 had incomplete resection. The group with complete resection showed a better survival than incomplete resection group (p =0.0001). Nineteen patients with complete resection had tumor recurrence. The recurrent rate was 68%. Patients having been disease-free for more than 12 months showed to have better survival than those less than 12 months (p =0.005). Aggressive surgical resection was done in case of tumor recurrence. Patients who received more than 2 (≥3) operations also showed a better survival than those with less than 2 operations (p =0.0247). Conclusions. Complete surgical resection and aggressive repeated surgical intervention are the most effective treatment modality for better survival in patients with retroperitoneal sarcoma.

Original languageEnglish
Pages (from-to)177-182
Number of pages6
JournalChinese Medical Journal (Taipei)
Volume58
Issue number3
StatePublished - Sep 1996

Keywords

  • Complete resection
  • Disease-free interval
  • Retroperitoneal sarcoma

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