Surface-Enhanced Raman Spectroscopy of the Catecholamine Neurotransmitters and Related Compounds

Nam soo Lee; You-Zung Hsieh; Richard F. Paisley; Michael D. Morris

doi:10.1021/ac00156a014

Surface-Enhanced Raman Spectroscopy of the Catecholamine Neurotransmitters and Related Compounds

Nam soo Lee^*, You-Zung Hsieh, Richard F. Paisley, Michael D. Morris

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

The surface-enhanced Raman spectra (SERS) of dopamine, norepinephrine, epinephrine, epinine isoproterenol 3-meth-oxytyramine, and catechol In pH 7.2 buffers on a silver electrode are reported. Catechol and the catecholamines are shown to be coordinated to silver through both oxygens. The methoxylated derivative Is a monodentate complex. Intensities maximize near -0.9 V vs saturated calomel electrode. The strongest bands in the spectra are phenolic carbon-ox-ygen stretches and the V_19bmodes around 1270 and 1480 cm^-1 respectively. Ascorbate, acetylcholine, glutathione, L-Dopa, and the catecholamine acetic acid metabolites are SERS-inactive under the measurement conditions. Dopamine detection limit for the vieb band is 3 X 10^-7M with a 10-s measurement time.

Original language	English
Pages (from-to)	442-446
Number of pages	5
Journal	Analytical Chemistry
Volume	60
Issue number	5
DOIs	https://doi.org/10.1021/ac00156a014
State	Published - 1 Mar 1988

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title = "Surface-Enhanced Raman Spectroscopy of the Catecholamine Neurotransmitters and Related Compounds",

abstract = "The surface-enhanced Raman spectra (SERS) of dopamine, norepinephrine, epinephrine, epinine isoproterenol 3-meth-oxytyramine, and catechol In pH 7.2 buffers on a silver electrode are reported. Catechol and the catecholamines are shown to be coordinated to silver through both oxygens. The methoxylated derivative Is a monodentate complex. Intensities maximize near -0.9 V vs saturated calomel electrode. The strongest bands in the spectra are phenolic carbon-ox-ygen stretches and the V19bmodes around 1270 and 1480 cm-1 respectively. Ascorbate, acetylcholine, glutathione, L-Dopa, and the catecholamine acetic acid metabolites are SERS-inactive under the measurement conditions. Dopamine detection limit for the vieb band is 3 X 10-7M with a 10-s measurement time.",

author = "Lee, {Nam soo} and You-Zung Hsieh and Paisley, {Richard F.} and Morris, {Michael D.}",

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T1 - Surface-Enhanced Raman Spectroscopy of the Catecholamine Neurotransmitters and Related Compounds

AU - Lee, Nam soo

AU - Hsieh, You-Zung

AU - Paisley, Richard F.

AU - Morris, Michael D.

PY - 1988/3/1

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N2 - The surface-enhanced Raman spectra (SERS) of dopamine, norepinephrine, epinephrine, epinine isoproterenol 3-meth-oxytyramine, and catechol In pH 7.2 buffers on a silver electrode are reported. Catechol and the catecholamines are shown to be coordinated to silver through both oxygens. The methoxylated derivative Is a monodentate complex. Intensities maximize near -0.9 V vs saturated calomel electrode. The strongest bands in the spectra are phenolic carbon-ox-ygen stretches and the V19bmodes around 1270 and 1480 cm-1 respectively. Ascorbate, acetylcholine, glutathione, L-Dopa, and the catecholamine acetic acid metabolites are SERS-inactive under the measurement conditions. Dopamine detection limit for the vieb band is 3 X 10-7M with a 10-s measurement time.

AB - The surface-enhanced Raman spectra (SERS) of dopamine, norepinephrine, epinephrine, epinine isoproterenol 3-meth-oxytyramine, and catechol In pH 7.2 buffers on a silver electrode are reported. Catechol and the catecholamines are shown to be coordinated to silver through both oxygens. The methoxylated derivative Is a monodentate complex. Intensities maximize near -0.9 V vs saturated calomel electrode. The strongest bands in the spectra are phenolic carbon-ox-ygen stretches and the V19bmodes around 1270 and 1480 cm-1 respectively. Ascorbate, acetylcholine, glutathione, L-Dopa, and the catecholamine acetic acid metabolites are SERS-inactive under the measurement conditions. Dopamine detection limit for the vieb band is 3 X 10-7M with a 10-s measurement time.

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JO - Analytical Chemistry

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Surface-Enhanced Raman Spectroscopy of the Catecholamine Neurotransmitters and Related Compounds

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