Superrepellent Doubly Reentrant Geometry Promotes Antibiofouling and Prevention of Coronavirus Contamination

Meng Shiue Lee, Yueh Chien, Pai Chi Teng, Xuan Yang Huang, Yi Ying Lin, Ting Yi Lin, Shih Jie Chou, Chian Shiu Chien, Yu Jer Hsiao, Yi Ping Yang, Wensyang Hsu, Shih Hwa Chiou*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The fomite transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has drawn attention because of its highly contagious nature. Therefore, surfaces that can prevent coronavirus contamination are an urgent and unmet need during the coronavirus disease 2019 (COVID-19) pandemic. Conventional surfaces are usually based on superhydrophobic or antiviral coatings. However, these coatings may be dysfunctional because of biofouling, which is the undesired adhesion of biomolecules. A superhydrophobic surface independent of the material content and coating agents may serve the purpose of antibiofouling and preventing viral transmission. Doubly reentrant topology (DRT) is a unique structure that can meet the need. This study demonstrates that the DRT surfaces possess a striking antibiofouling effect that can prevent viral contamination. This effect still exists even if the DRT surface is made of a hydrophilic material such as silicon oxide and copper. To the best of our knowledge, this work first demonstrates that fomite transmission of viruses may be prevented by minimizing the contact area between pathogens and surfaces even made of hydrophilic materials. Furthermore, the DRT geometry per se features excellent antibiofouling ability, which may shed light on the applications of pathogen elimination in alleviating the COVID-19 pandemic.

Original languageEnglish
Article number2200387
JournalAdvanced Materials Technologies
Issue number1
StatePublished - 10 Jan 2023


  • COVID-19 pandemic
  • antibiofouling surfaces
  • doubly reentrant topology (DRT)
  • superrepellency


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