Spectroscopic study of bio-functionalized nanodiamonds

P. H. Chung; E. Perevedentseva; J. S. Tu; Chia-Ching Chang; C. L. Cheng

doi:10.1016/j.diamond.2005.11.019

Spectroscopic study of bio-functionalized nanodiamonds

P. H. Chung, E. Perevedentseva, J. S. Tu, Chia-Ching Chang, C. L. Cheng^*

^*Corresponding author for this work

Department of Biological Science and Technology

Research output: Contribution to journal › Article › peer-review

193 Scopus citations

Abstract

Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biomolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy.

Original language	English
Pages (from-to)	622-625
Number of pages	4
Journal	Diamond and Related Materials
Volume	15
Issue number	4-8
DOIs	https://doi.org/10.1016/j.diamond.2005.11.019
State	Published - Apr 2006

Keywords

Biomedical applications
Nanodiamonds
Sensors
Surface characterization

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10.1016/j.diamond.2005.11.019

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title = "Spectroscopic study of bio-functionalized nanodiamonds",

abstract = "Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biomolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy.",

keywords = "Biomedical applications, Nanodiamonds, Sensors, Surface characterization",

author = "Chung, {P. H.} and E. Perevedentseva and Tu, {J. S.} and Chia-Ching Chang and Cheng, {C. L.}",

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T1 - Spectroscopic study of bio-functionalized nanodiamonds

AU - Chung, P. H.

AU - Perevedentseva, E.

AU - Tu, J. S.

AU - Chang, Chia-Ching

AU - Cheng, C. L.

PY - 2006/4

Y1 - 2006/4

N2 - Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biomolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy.

AB - Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biomolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy.

KW - Biomedical applications

KW - Nanodiamonds

KW - Sensors

KW - Surface characterization

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DO - 10.1016/j.diamond.2005.11.019

M3 - Article

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SN - 0925-9635

VL - 15

SP - 622

EP - 625

JO - Diamond and Related Materials

JF - Diamond and Related Materials

IS - 4-8

ER -

Spectroscopic study of bio-functionalized nanodiamonds

Abstract

Keywords

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