Semiconducting polymer nanoparticles as fluorescent probes for biological imaging and sensing

Yang-Hsiang Chan*, Pei Jing Wu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

124 Scopus citations


In recent years, semiconducting polymer nanoparticles have emerged as a new class of extraordinarily bright fluorescent probes. These polymer nanoparticles, which are primarily composed of π-conjugated polymers, exhibit a variety of outstanding features, including exceptional fluorescence brightness, fast radiative rate, good photostability, facile surface functionalization, and low cytotoxicity. These advantageous characteristics make polymer nanoparticles highly promising for applications in biological imaging and sensing. This progress report highlights recent advances in the synthesis, characterization, and applications as bio-labels or sensors of these highly emissive organic nanoparticles.

Original languageEnglish
Pages (from-to)11-28
Number of pages18
JournalParticle and Particle Systems Characterization
Issue number1
StatePublished - 1 Jan 2015


  • Bioimaging
  • Fluorescence
  • FRET sensors
  • Polymer dots
  • Semiconducting polymers


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