TY - JOUR
T1 - Semiconducting polymer dots as near-infrared fluorescent probes for bioimaging and sensing
AU - Tsai, Wei Kai
AU - Chan, Yang-Hsiang
PY - 2019/1/1
Y1 - 2019/1/1
N2 - In recent years, semiconducting polymer dots (Pdots) have emerged as a new type of ultrabright fluorescent probes, which have been proved to be very useful for biomedical imaging. Pdots possess several exceptional advantages including high fluorescence brightness, fast radiative rate, excellent photostability, and negligible cytotoxicity. Among these new types of Pdots, the near-infrared (NIR) fluorescent Pdots appear to be the most urgent and important owing to their promising deep-tissue imaging in the clinic. This mini-review highlights the recent progress in the design of NIR-emitting Pdots and their biomedical applications both in vitro and in vivo.
AB - In recent years, semiconducting polymer dots (Pdots) have emerged as a new type of ultrabright fluorescent probes, which have been proved to be very useful for biomedical imaging. Pdots possess several exceptional advantages including high fluorescence brightness, fast radiative rate, excellent photostability, and negligible cytotoxicity. Among these new types of Pdots, the near-infrared (NIR) fluorescent Pdots appear to be the most urgent and important owing to their promising deep-tissue imaging in the clinic. This mini-review highlights the recent progress in the design of NIR-emitting Pdots and their biomedical applications both in vitro and in vivo.
KW - analytical detection
KW - in vivo imaging
KW - near-infrared
KW - semiconducting polymer dots
UR - http://www.scopus.com/inward/record.url?scp=85056344345&partnerID=8YFLogxK
U2 - 10.1002/jccs.201800322
DO - 10.1002/jccs.201800322
M3 - Review article
AN - SCOPUS:85056344345
SN - 0009-4536
VL - 66
SP - 9
EP - 20
JO - Journal of the Chinese Chemical Society
JF - Journal of the Chinese Chemical Society
IS - 1
ER -