Original language | English |
---|---|
Article number | 106872 |
Journal | Leukemia Research |
Volume | 118 |
DOIs | |
State | Published - Jul 2022 |
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In: Leukemia Research, Vol. 118, 106872, 07.2022.
Research output: Contribution to journal › Letter › peer-review
TY - JOUR
T1 - ROR1 targeted immunoliposomal delivery of OSU-2S shows selective cytotoxicity in t(1;19)(q23;p13) translocated B-cell acute lymphoblastic leukemia
AU - Goswami, Swagata
AU - Chiang, Chi Ling
AU - Zapolnik, Kevan
AU - Nunes, Jessica
AU - Ventura, Ann
AU - Mo, Xiaokui
AU - Xie, Zhiliang
AU - Lee, L. James
AU - Baskar, Sivasubramanian
AU - Rader, Christoph
AU - Byrd, John C.
AU - Phelps, Mitch
AU - Bhatnagar, Bhavana
AU - Muthusamy, Natarajan
N1 - Funding Information: The authors are grateful to the ALL patients who contributed to these studies, the Ohio State University (OSU) Comprehensive Cancer Center Leukemia Tissue Bank Shared Resource (P30CA016058), USA. This work was supported by National Institute of Health (NIH, USA) R01-CA197844-01, R35 CA197734, P50-CA140158, OSU Division of Hematology DSRP (NM and BB), Robert J. Anthony Leukemia Fund (USA). SG is funded by National Cancer Institute (NCI, USA) 1F99CA245813-01 and previously by OSU Pelotonia Graduate Fellowship. SG planned, designed and performed the experiments, analyzed data, wrote the drafts of the paper. CL, KZ, XZ assisted with the experiments. X.M. performed the statistical analysis. JL, SB, CR, JCB and MP provided necessary reagents, supported components of the research. JCB and BB contributed to the patient care and/or provided translation insight to the study. NM conceived the idea, designed experiments, supervised the study, sought funding, reviewed drafts and approved the final version for submission. All authors reviewed the data and the manuscript, and agreed with submission for publication. NM and JCB are co-inventors of OSU-2S for which The Ohio State University owns the patent. CR and SB are co-inventors of mAb 2A2 for which the NIH owns the patent. Funding Information: The authors are grateful to the ALL patients who contributed to these studies, the Ohio State University (OSU) Comprehensive Cancer Center Leukemia Tissue Bank Shared Resource ( P30CA016058 ), USA. This work was supported by National Institute of Health (NIH, USA) R01-CA197844-01 , R35 CA197734 , P50-CA140158 , OSU Division of Hematology DSRP (NM and BB), Robert J. Anthony Leukemia Fund (USA). SG is funded by National Cancer Institute (NCI, USA) 1F99CA245813-01 and previously by OSU Pelotonia Graduate Fellowship.
PY - 2022/7
Y1 - 2022/7
UR - http://www.scopus.com/inward/record.url?scp=85130879845&partnerID=8YFLogxK
U2 - 10.1016/j.leukres.2022.106872
DO - 10.1016/j.leukres.2022.106872
M3 - Letter
C2 - 35640397
AN - SCOPUS:85130879845
SN - 0145-2126
VL - 118
JO - Leukemia Research
JF - Leukemia Research
M1 - 106872
ER -