Resuscitation of newborn infants with oxygen

Min Hsueh Weng*, Cheng Chen Chou, Hung Chieh Chou, Tsorng Yeh Lee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The metabolites of reoxygenation accumulate as toxic free radicals during physiological reactions. During an episode of asphyxia, 100% oxygen rather than 21% oxygen is usually used for resuscitation. Excessive free radicals and cell injury may be produced during reoxygenation following the hypoxic event. Prior research has shown that resuscitation with room air (21% oxygen) may be equally effective as 100% oxygen. The side effects are also less with room air. However, evidence-based studies on this topic are limited. It is, therefore, more appropriate to follow the recommendation of Neonatal Resuscitation Program that 100% oxygen should be used during neonatal resuscitation and the oxygen concentration should be adjusted according to the different condition of individual infants.

Original languageEnglish
Pages (from-to)81-84
Number of pages4
JournalJournal of Nursing
Issue number1
StatePublished - Feb 2004


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