Repetitive elements in the third intron of murine apolipoprotein A-I gene

An Na Chiang; Kong Chi Fan; Gwo Chyuan Shaw; Ueng Cheng Yang

doi:10.1080/15216549700204801

Repetitive elements in the third intron of murine apolipoprotein A-I gene

An Na Chiang^*, Kong Chi Fan, Gwo Chyuan Shaw, Ueng Cheng Yang

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Genomic DNAs containing the gene encoding apolipoprotein A-I (apoA-I) from four strains of mice and three strains of rats have been sequenced, Some peculiar repetitive sequences were found in the third intron of apoA-I of the murine species. The striking features include regular tandem repeats of C(A)₄ and C(A)₆ in mice and long A-tracts in rats. Not completely identical but very similar motifs were found in mice or rats belonging to the same species while repetitive elements from different species show some variation from their species-specific consensus sequences. These repetitive motifs are very similar to the sequences flanking human Alu and rodent B1 repetitive elements, although no evidence for the existence of Alu or B1 was found near the peculiar repetitive DNA sequences in apoA-I gene.

Original language	English
Pages (from-to)	989-996
Number of pages	8
Journal	Biochemistry and Molecular Biology International
Volume	43
Issue number	5
DOIs	https://doi.org/10.1080/15216549700204801
State	Published - 1997

Keywords

Apolipoprotein A-I
Mouse
Nucleotide sequence
Rat
Repetitive elements

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title = "Repetitive elements in the third intron of murine apolipoprotein A-I gene",

abstract = "Genomic DNAs containing the gene encoding apolipoprotein A-I (apoA-I) from four strains of mice and three strains of rats have been sequenced, Some peculiar repetitive sequences were found in the third intron of apoA-I of the murine species. The striking features include regular tandem repeats of C(A)4 and C(A)6 in mice and long A-tracts in rats. Not completely identical but very similar motifs were found in mice or rats belonging to the same species while repetitive elements from different species show some variation from their species-specific consensus sequences. These repetitive motifs are very similar to the sequences flanking human Alu and rodent B1 repetitive elements, although no evidence for the existence of Alu or B1 was found near the peculiar repetitive DNA sequences in apoA-I gene.",

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author = "Chiang, {An Na} and Fan, {Kong Chi} and Shaw, {Gwo Chyuan} and Yang, {Ueng Cheng}",

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TY - JOUR

T1 - Repetitive elements in the third intron of murine apolipoprotein A-I gene

AU - Chiang, An Na

AU - Fan, Kong Chi

AU - Shaw, Gwo Chyuan

AU - Yang, Ueng Cheng

PY - 1997

Y1 - 1997

N2 - Genomic DNAs containing the gene encoding apolipoprotein A-I (apoA-I) from four strains of mice and three strains of rats have been sequenced, Some peculiar repetitive sequences were found in the third intron of apoA-I of the murine species. The striking features include regular tandem repeats of C(A)4 and C(A)6 in mice and long A-tracts in rats. Not completely identical but very similar motifs were found in mice or rats belonging to the same species while repetitive elements from different species show some variation from their species-specific consensus sequences. These repetitive motifs are very similar to the sequences flanking human Alu and rodent B1 repetitive elements, although no evidence for the existence of Alu or B1 was found near the peculiar repetitive DNA sequences in apoA-I gene.

AB - Genomic DNAs containing the gene encoding apolipoprotein A-I (apoA-I) from four strains of mice and three strains of rats have been sequenced, Some peculiar repetitive sequences were found in the third intron of apoA-I of the murine species. The striking features include regular tandem repeats of C(A)4 and C(A)6 in mice and long A-tracts in rats. Not completely identical but very similar motifs were found in mice or rats belonging to the same species while repetitive elements from different species show some variation from their species-specific consensus sequences. These repetitive motifs are very similar to the sequences flanking human Alu and rodent B1 repetitive elements, although no evidence for the existence of Alu or B1 was found near the peculiar repetitive DNA sequences in apoA-I gene.

KW - Apolipoprotein A-I

KW - Mouse

KW - Nucleotide sequence

KW - Rat

KW - Repetitive elements

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EP - 996

JO - Biochemistry and Molecular Biology International

JF - Biochemistry and Molecular Biology International

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Repetitive elements in the third intron of murine apolipoprotein A-I gene

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