Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

Shang Hsiu Hu; You Yin Chen; Ta Chung Liu; Tsan Hua Tung; Dean Mo Liu; San Yuan Chen

doi:10.1039/c0cc03998e

Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

Shang Hsiu Hu, You Yin Chen, Ta Chung Liu, Tsan Hua Tung, Dean Mo Liu^*, San Yuan Chen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Yolk/shell capsules containing a volume/hydrophobicity transformable core and an ultra-thin silica shell have been prepared. When an external magnetic field induced the temperature, the cores exhibit a significant triggering size shrinkage and the diameter decreases more than 10 times, causing solid shells destruction and physical collapse, leading to drug burst release.

Original language	English
Pages (from-to)	1776-1778
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	6
DOIs	https://doi.org/10.1039/c0cc03998e
State	Published - 14 Feb 2011

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title = "Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release",

abstract = "Yolk/shell capsules containing a volume/hydrophobicity transformable core and an ultra-thin silica shell have been prepared. When an external magnetic field induced the temperature, the cores exhibit a significant triggering size shrinkage and the diameter decreases more than 10 times, causing solid shells destruction and physical collapse, leading to drug burst release.",

author = "Hu, {Shang Hsiu} and Chen, {You Yin} and Liu, {Ta Chung} and Tung, {Tsan Hua} and Liu, {Dean Mo} and Chen, {San Yuan}",

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AU - Chen, You Yin

AU - Liu, Ta Chung

AU - Tung, Tsan Hua

AU - Liu, Dean Mo

AU - Chen, San Yuan

PY - 2011/2/14

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AB - Yolk/shell capsules containing a volume/hydrophobicity transformable core and an ultra-thin silica shell have been prepared. When an external magnetic field induced the temperature, the cores exhibit a significant triggering size shrinkage and the diameter decreases more than 10 times, causing solid shells destruction and physical collapse, leading to drug burst release.

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JO - Chemical Communications

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Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

Abstract

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