Recent patents on the baculovirus systems

Shih Yeh Lin, Guan-Yu Chen, Yu Chen Hu*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Baculovirus has been widely utilized as a protein production tool in insect cells for nearly 3 decades and has captured growing interests as a vector for gene delivery into mammalian cells and animals over the past decade. This review summarizes important patents pertaining to the use of baculovirus for insect cell infection and mammalian cell transduction, with special emphasis on the vector development, new applications and downstream processing.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalRecent Patents on Biotechnology
Volume5
Issue number1
DOIs
StatePublished - 2011

Keywords

  • Baculovirus
  • Expression system
  • Insect cell
  • Mammalian cell
  • Vaccine

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