Real-time bioluminescent assay for inhibitors of RNA and DNA polymerases and other ATP-dependent enzymes

Keyphrases

• RNA-dependent RNA Polymerase (RdRP) 100%
• Polymerase 100%
• Bioluminescent Assay 100%
• DNA Polymerase 100%
• ATP-dependent Enzymes 100%
• Change of Measure 50%
• Drug Development 50%
• Kinetic Study 50%
• Inhibition Mechanism 50%
• Inhibition Constant 50%
• Inhibitor Concentration 50%
• Viral Polymerase 50%
• Substrate Concentration 50%
• RNA Template 50%
• Michaelis-Menten 50%
• Non-competitive Inhibitor 50%
• Competitive Inhibitor 50%
• Klenow Fragment 50%
• Km Value 50%
• HIV-1 Reverse Transcriptase 50%
• Enzyme Inhibition 50%
• Number of Experiments 50%
• DNA Template 50%
• Fragment-based Drug Discovery 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Adenosine Triphosphate 100%
• RNA Polymerase 100%
• DNA Polymerase 100%
• Drug Development 25%
• Drug Discovery 25%
• RNA Directed DNA Polymerase 25%
• Competitive Inhibitor 25%
• Enzyme Inhibition 25%