Reactant cost minimization through target concentration selection on microfluidic biochips

Yung Chun Lei; Yi Ling Chen; Juinn-Dar Huang

doi:10.1109/BioCAS.2016.7833724

Reactant cost minimization through target concentration selection on microfluidic biochips

Yung Chun Lei, Yi Ling Chen, Juinn-Dar Huang

Institute of Electronics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

4 Scopus citations

Abstract

Nowadays, lab-on-a-chip is one of the most sophisticated technologies, while sample preparation, one of the essential steps in bioassays, is the process that mixes buffer and reactant to achieve the desired target concentration. Since the reactant consumption generally takes a notable part of the total cost in a bioassay, minimizing its usage is generally preferable. Existing techniques only consider one fixed target concentration, whereas a range of values is acceptable in real applications. In this paper, we propose two algorithms that can select a feasible concentration value within a given range for cost minimization. Experimental results show that the proposed methods can further reduce the reactant cost up to 20%.

Original language	English
Title of host publication	Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	58-61
Number of pages	4
ISBN (Electronic)	9781509029594
DOIs	https://doi.org/10.1109/BioCAS.2016.7833724
State	Published - 1 Jan 2016
Event	12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016 - Shanghai, China Duration: 17 Oct 2016 → 19 Oct 2016

Publication series

Name	Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016

Conference

Conference	12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016
Country/Territory	China
City	Shanghai
Period	17/10/16 → 19/10/16

Keywords

microfluidic biochip
reactant cost minimization
sample preparation
target concentration selection

Access to Document

10.1109/BioCAS.2016.7833724

Cite this

Lei, Y. C., Chen, Y. L., & Huang, J.-D. (2016). Reactant cost minimization through target concentration selection on microfluidic biochips. In Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016 (pp. 58-61). Article 7833724 (Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS.2016.7833724

Lei, Yung Chun ; Chen, Yi Ling ; Huang, Juinn-Dar. / Reactant cost minimization through target concentration selection on microfluidic biochips. Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016. Institute of Electrical and Electronics Engineers Inc., 2016. pp. 58-61 (Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016).

@inproceedings{96270a0fa1c24bdeaefa07bb10fa5905,

title = "Reactant cost minimization through target concentration selection on microfluidic biochips",

abstract = "Nowadays, lab-on-a-chip is one of the most sophisticated technologies, while sample preparation, one of the essential steps in bioassays, is the process that mixes buffer and reactant to achieve the desired target concentration. Since the reactant consumption generally takes a notable part of the total cost in a bioassay, minimizing its usage is generally preferable. Existing techniques only consider one fixed target concentration, whereas a range of values is acceptable in real applications. In this paper, we propose two algorithms that can select a feasible concentration value within a given range for cost minimization. Experimental results show that the proposed methods can further reduce the reactant cost up to 20%.",

keywords = "microfluidic biochip, reactant cost minimization, sample preparation, target concentration selection",

author = "Lei, {Yung Chun} and Chen, {Yi Ling} and Juinn-Dar Huang",

year = "2016",

month = jan,

day = "1",

doi = "10.1109/BioCAS.2016.7833724",

language = "English",

series = "Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "58--61",

booktitle = "Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016",

address = "美國",

note = "12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016 ; Conference date: 17-10-2016 Through 19-10-2016",

}

Lei, YC, Chen, YL & Huang, J-D 2016, Reactant cost minimization through target concentration selection on microfluidic biochips. in Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016., 7833724, Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016, Institute of Electrical and Electronics Engineers Inc., pp. 58-61, 12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016, Shanghai, China, 17/10/16. https://doi.org/10.1109/BioCAS.2016.7833724

Reactant cost minimization through target concentration selection on microfluidic biochips. / Lei, Yung Chun; Chen, Yi Ling; Huang, Juinn-Dar.
Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. 58-61 7833724 (Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Reactant cost minimization through target concentration selection on microfluidic biochips

AU - Lei, Yung Chun

AU - Chen, Yi Ling

AU - Huang, Juinn-Dar

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Nowadays, lab-on-a-chip is one of the most sophisticated technologies, while sample preparation, one of the essential steps in bioassays, is the process that mixes buffer and reactant to achieve the desired target concentration. Since the reactant consumption generally takes a notable part of the total cost in a bioassay, minimizing its usage is generally preferable. Existing techniques only consider one fixed target concentration, whereas a range of values is acceptable in real applications. In this paper, we propose two algorithms that can select a feasible concentration value within a given range for cost minimization. Experimental results show that the proposed methods can further reduce the reactant cost up to 20%.

AB - Nowadays, lab-on-a-chip is one of the most sophisticated technologies, while sample preparation, one of the essential steps in bioassays, is the process that mixes buffer and reactant to achieve the desired target concentration. Since the reactant consumption generally takes a notable part of the total cost in a bioassay, minimizing its usage is generally preferable. Existing techniques only consider one fixed target concentration, whereas a range of values is acceptable in real applications. In this paper, we propose two algorithms that can select a feasible concentration value within a given range for cost minimization. Experimental results show that the proposed methods can further reduce the reactant cost up to 20%.

KW - microfluidic biochip

KW - reactant cost minimization

KW - sample preparation

KW - target concentration selection

UR - http://www.scopus.com/inward/record.url?scp=85014223662&partnerID=8YFLogxK

U2 - 10.1109/BioCAS.2016.7833724

DO - 10.1109/BioCAS.2016.7833724

M3 - Conference contribution

AN - SCOPUS:85014223662

T3 - Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016

SP - 58

EP - 61

BT - Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016

Y2 - 17 October 2016 through 19 October 2016

ER -

Lei YC, Chen YL, Huang JD. Reactant cost minimization through target concentration selection on microfluidic biochips. In Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016. Institute of Electrical and Electronics Engineers Inc. 2016. p. 58-61. 7833724. (Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016). doi: 10.1109/BioCAS.2016.7833724

Reactant cost minimization through target concentration selection on microfluidic biochips

Abstract

Publication series

Conference

Keywords

Access to Document

Other files and links

Fingerprint

Cite this